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Evaluation and visualisation of surface defects on auto-body panels
The ability to predict surface defects in outer panels is of vital importance in the automotive industry, especially for brands in the premium car segment. Today, measures to prevent these defects cannot be taken until a test part has been manufactured, which requires a great deal of time and expense. The decision as to whether a certain surface is of acceptable quality or not is based on subjecti
Precipitation as driver of carbon fluxes in 11 African ecosystems
This study reports carbon and water fluxes between the land surface and atmosphere in eleven different ecosystems types in Sub-Saharan Africa, as measured using eddy covariance (EC) technology in the first two years of the CarboAfrica network operation. The ecosystems for which data were available ranged in mean annual rainfall from 320 mm (Sudan) to 1150 mm (Republic of Congo) and include a spect
ADAM12 is a four-leafed clover - The excised prodomain remains bound to the mature enzyme
The ADAMs (a disintegrin and metalloprotease) comprise a family of multidomain proteins with metalloprotease, cell adhesion, and signaling activities. Human ADAM12, which is implicated in diseases such as cancer, is expressed in two splice forms, the transmembrane ADAM12-L and the shorter and soluble ADAM12-S. ADAM12 is synthesized as a zymogen with the prodomain keeping the metalloprotease inacti
A phase 3 randomized controlled trial of the efficacy and safety of atrasentan in men with metastatic hormone-refractory prostate cancer
BACKGROUND. The objective of this study was to evaluate the efficacy and safety of atrasentan (Xinlay), a selective endothelin-A receptor antagonist, in patients with metastatic hormone- refractory prostate cancer (HRPC). METHODS. This multinational, double-blind, placebo-controlled trial enrolled 809 men with metastatic HRPC. Patients were randomized 1:1 to receive either atrasentan 10 mg per day
A Cordylodus fauna from the SW Gulf of Bothnia, Sweden
A conodont fauna including several species of Cordylodus was retrieved from two glacial siltstone boulders found on the shore of Lilltuppen, a small island immediately off the Swedish coast in the Gulf of Bothnia at c. 61 degrees N, 17 degrees E. The erratics are remnants of a poorly known level in the Swedish stratigraphic succession. They probably derive from a nearby point on the floor of the B
Identification of numerical and structural chromosome aberrations in 15 high hyperdiploid childhood acute lymphoblastic leukemias using spectral karyotyping
Spectral karyotyping (SKY) on metaphase spreads from 15 high hyperdiploid (>51 chromosomes) childhood acute lymphoblastic leukemias (ALL), which typically display a poor chromosome morphology, was performed in order to investigate the pattern of numerical abnormalities, reveal the chromosomal origin of marker chromosomes, and identify translocations and other interchromosomal rearrangements not de
Contribution of suspended and sorbed groundwater bacteria to degradation of dissolved and sorbed aniline
The influence of sorption on the mineralisation of 50 mug aniline l(-1) was examined in an aquifer material under batch conditions. The study was designed to distinguish the rates and extent of biodegradation of the sorbed and the dissolved trace organic and the contribution of sorbed and suspended bacteria to the degradation. Four different mathematical models were developed with different assump
Effects of ghrelin on insulin and glucagon secretion: a study of isolated pancreatic islets and intact mice.
Measuring Fatigue in Parkinson's Disease: A Psychometric Study of Two Brief Generic Fatigue Questionnaires.
On the effect of lactic acid on blood glucose and insulin responses to cereal products: Mechanistic studies in healthy subjects and in vitro
It has been observed that bread containing lactic acid produced during the sourdough fermentation or added directly, has the ability to lower the postprandial glucose and insulin responses in humans. The main objective of the present work was to evaluate the possible mechanisms for a lowered glucose response to bread containing lactic acid, and to determine whether the same phenomenon also occurs
Menarche in women with high exposure to persistent organochlorine pollutants in utero and during childhood.
Cricopharyngeal bar: myth and reality
Using the cue elimination technique to derive an equation between performance in episodic tests
Lawful equations describing relations between empirical measurable variables, that are free of fitted parameters, and that can be derived from simple assumptions, are rare in psychology. However, this paper proposes one such equation that describes the relation between the performances on four different explicit episodic memory tests: free recall, cued recall, recognition, and cued recognition. Th
Working memory training decreases hippocampal neurogenesis.
The relationship between adult hippocampal neurogenesis and cognition appears more complex than suggested by early reports. We aimed to determine if the duration and task demands of spatial memory training differentially affect hippocampal neurogenesis. Adult male rats were trained in the Morris water maze in a reference memory task for 4 days, or alternatively working memory for either 4 or 14 da
Why do women with early RA respond less well to MTX than men? Gender as a determinant of response in the initial phase of the Swefot trial
Breast cancer-amplified sequence 3, a target of metastasis-associated protein 1, contributes to tamoxifen resistance in premenopausal patients with breast cancer
Lysine acetylation occurs in many protein targets, including core histones, transcription factors, and other proteins. Metastasis-associated protein 1 (MTA1) is implicated in the progression and metastasis of various epithelial tumors. Because MTA1 functions as a transcriptional coregulator, much of its role in cancer promoting processes are likely to involve its ability to regulate the transcript
Improving InAs nanotree growth with composition-controlled Au-In nanoparticles
Au nanoparticles are commonly used as seeds for epitaxial growth of III-V semiconductor nanowires. However, the interaction between Au and In-containing III-V materials makes it difficult to control the growth of more complex nanowire structures in materials such as InAs. Here we report the growth of InAs nanowires and branched nanotrees using Au and Au-In nanoparticles. We show that the initial c
Time span and spatial scale of regional new particle formation events over Finland and Southern Sweden
We investigated the time span and spatial scale of regional new particle formation (NPF) events in Finland and Southern Sweden using measured particle number size distributions at five background stations. We define the time span of a NPF event as the time period from the first moment when the newly formed mode of aerosol particles is observable below 25 nm until the newly formed mode is not any m
Tone 4 and Tone 3 discrimination in Modern Standard Chinese
Productions of tone 4 & tone 3 (mai/mai 'sell'/'buy') in comparable sentences suggests that although the two tones are realized in different ways by different speakers in different speech acts, some features are constant. Tone 3 is connected with a low pitch level throughout the second half of the vowel & tone 4 with a gradual fall over the main part of the vocalic segment. These observati
