Search results

Filter

Filetype

Your search for "*" yielded 530930 hits

Revisiting the classification of clinical phenotypes of anti-neutrophil cytoplasmic antibody-associated vasculitis: a cluster analysis

Background Granulomatosis with polyangiitis (Wegener's) (GPA) and microscopic polyangiitis (MPA) are subgroups of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) defined historically by clinical and histological features. GPA and MPA are heterogeneous entities with overlapping phenotypes. To identify novel subgroupings, cluster analysis was used to explore the phenotypic sp

Datorreglering av klimatprocesser

Syftet har varit att ta fram grundläggande teknisk och ekonomisk kunskap för datorreglering av klimatprocesser. En kontorsbyggnad, vars klimatanläggning är datorstyrd, har använts som försöksobjekt. Som resultat av undersökningen ges synpunkter och krav på funktion och programvara för signaler, övervakning, styrning, optimering osv.

High expression of RNA-binding motif protein 3 in esophageal and gastric adenocarcinoma correlates with intestinal metaplasia-associated tumours and independently predicts a reduced risk of recurrence and death.

High nuclear expression of the RNA-binding motif protein 3 (RBM3) has previously been found to correlate with favourable clinicopathological characteristics and a prolonged survival in several cancer forms. Here, we examined the clinicopathological correlates and prognostic significance of RBM3 expression in tumours from a consecutive cohort of upper gastrointestinal adenocarcinoma.

Microglia Acquire Distinct Activation Profiles Depending on the Degree of alpha-Synuclein Neuropathology in a rAAV Based Model of Parkinson's Disease

Post-mortem analysis of brains from Parkinson's disease (PD) patients strongly supports microglia activation and adaptive immunity as factors contributing to disease progression. Such responses may be triggered by alpha-synuclein (alpha-syn), which is known to be the main constituent of the aggregated proteins found in Lewy bodies in the brains of PD patients. To investigate this we used a recombi

Adaptation as a Means of Reflecting upon Immersivity and Self-Referentiality

In this article, I will apply parts of the method introduced by Linda Hutcheon in her recently reedited book A Theory of Adaptation (2010) and try to answer the question “why” an adaptation is made. I will particularly study three complex cases of adaptation, which might even put into question the definition of adaptation itself, but I will concentrate on aspects related to immersion and self-refe

Sample size re-assessment leading to a raised sample size does not inflate type I error rate under mild conditions.

One major concern with adaptive designs, such as the sample size adjustable designs, has been the fear of inflating the type I error rate. In (Stat Med 23:1023-1038, 2004) it is however proven that when observations follow a normal distribution and the interim result show promise, meaning that the conditional power exceeds 50%, type I error rate is protected. This bound and the distributional assu

Testing avian compass calibration: comparative experiments with diurnal and nocturnal passerine migrants in South Sweden.

Cue-conflict experiments were performed to study the compass calibration of one predominantly diurnal migrant, the dunnock (Prunella modularis), and two species of nocturnal passerine migrants, the sedge warbler (Acrocephalus schoenobaenus), and the European robin (Erithacus rubecula) during autumn migration in South Sweden. The birds' orientation was recorded in circular cages under natural clear

Autoantibodies as biomarkers for the prediction of neuropsychiatric events in systemic lupus erythematosus

Objective Neuropsychiatric events occur unpredictably in systemic lupus erythematosus (SLE) and most biomarker associations remain to be prospectively validated. This study examined a disease inception cohort of 1047 SLE patients to determine which autoantibodies at enrolment predicted subsequent neuropsychiatric events. Methods Patients with a recent SLE diagnosis were assessed prospectively for

Analysis of a high frequency and wide bandwidth active polyphase filter based on CMOS inverters

An active polyphase filter capable of high frequency quadrature signal generation has been analyzed. The resistors of the classical passive polyphase filter have been replaced by transconductors, CMOS inverters [1,2]. A three-stage 0.13 um CMOS active polyphase filter has been designed. Simulations with a differential input signal show a quadrature error less than 1◦ for the full stable input volt

Reglering av värmesystem i flerbostadshus med individuell värmemätning

Indoor temperatures in multifamily houses are indirectly controlled by the outdoor temperature. The radiator supply temperature is a function of the outdoor temperature. This control principle cannot take into account for disturbances from people, electric appliances, airing, sun, and air leakage due to wind. A control setting with a suitable margin can avoid complaints, but may result in overheat