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Exploring and comparing definitions of healthy vascular ageing in the population: characteristics and prospective cardiovascular risk.

Published 17 July 2020 Different methods can be used to define healthy vascular ageing (HVA). In this prospective cohort study, we explored three different definitions in order to provide guidance for which to use. 2718 subjects were included from the Cardiovascular (CV) arm of the Malmö Diet Cancer Study (MDCS; median age 71.9 years, 62.2% females). Three different definitions of HVA were used: H

https://www.lupop.lu.se/article/exploring-and-comparing-definitions-healthy-vascular-ageing-population-characteristics-and - 2025-01-07

The Role of Physical Activity on Parental Rejection and Body Image Perceptions

Published 17 July 2020 The present study investigated the potential moderating role of physical activity on the relationship between parental rejection and poor body image perceptions. Late adolescents and young adults from Turkey (N = 373; 256 females/117 males) reported their memories of upbringing (Egna Minnen Beträffande Uppfostran/EMBU) related to both their mother and father, respectively, l

https://www.lupop.lu.se/article/role-physical-activity-parental-rejection-and-body-image-perceptions - 2025-01-07

Cancer diagnoses among older people with intellectual disability compared with the general population: a national register study

Published 18 July 2020 People with ID who were ≥55years old and alive at the end of 2012 (n = 7936; ID cohort) were identified through a national register of people with ID who received social services in Sweden to optimise the individual's opportunity for good living conditions in daily life. An equally large reference cohort from the general population (gPop cohort) was matched by year of birth

https://www.lupop.lu.se/article/cancer-diagnoses-among-older-people-intellectual-disability-compared-general-population-national - 2025-01-07

Health-Related Quality of Life in Children With Earlier Surgical Repair for Right Ventricular Outflow Tract Anomalies and the Agreement Between Children and Their Parents

Published 18 July 2020 Children diagnosed with right ventricle outflow tract (RVOT) anomalies require surgical repair early in life, reoperations and lifelong follow-up. The aim is to comprehensively describe their health related quality of life (HRQoL) and to assess the agreement in this regard between children and parents. New publication in Front. Cardiovasc. Med.

https://www.lupop.lu.se/article/health-related-quality-life-children-earlier-surgical-repair-right-ventricular-outflow-tract - 2025-01-07

How registry data can improve outcomes from joint replacement – a seminal paper

Published 19 July 2020 Charnley, McKee and Ling, arguably the pioneers of Total Hip Replacement (THR), all recommended that there should be some sort of register for hip replacements. Perceptively, Sir John wrote in 1972: “Serious consideration should be given to establishing a Central Register to keep a finger on the pulse of total implant surgery on a nation-wide basis.” However, it was Peter He

https://www.lupop.lu.se/article/how-registry-data-can-improve-outcomes-joint-replacement-seminal-paper - 2025-01-07

Prediagnostic serum selenium levels in relation to breast cancer survival and tumor characteristics

Published 19 July 2020 Women with lower levels of serum selenium (Se) may have a worse survival in breast cancer than women with higher levels, despite no difference in incidence of the disease. Our study was conducted to test whether Se is associated with the aggressiveness of breast tumors. Both the risk of having a tumor characteristic associated with worse prognosis, as well as the overall and

https://www.lupop.lu.se/article/prediagnostic-serum-selenium-levels-relation-breast-cancer-survival-and-tumor-characteristics - 2025-01-07

Do patients or their physicians more accurately assess long-term risk associated with hypertension? A population-based study

Published 20 July 2020 Patients were significantly better (p < 0.001) than their physicians in estimating the average probability of heart failure compared with actual outcome data (14% vs. 24%, outcome 15%), AMI (16% vs. 26%, outcome 8%), and stroke (15% vs. 25%, outcome 11%). Patients were significantly worse (p < 0.001) at estimating the average probability of death (10% vs. 18%, actual outcome

https://www.lupop.lu.se/article/do-patients-or-their-physicians-more-accurately-assess-long-term-risk-associated-hypertension - 2025-01-07

Fast food outlets, physical activity facilities, and obesity among adults: a nationwide longitudinal study from Sweden

Published 20 July 2020 This study used multiple national register data from Sweden. During the 11-year follow-up period between 2005 and 2015, data from 1,167,449 men and 542,606 women, aged 20–55 years, were accessible for inclusion in this analysis. Incidence of obesity was identified based on a diagnosis of obesity during the follow-up period derived from clinical register data. Neighborhood av

https://www.lupop.lu.se/article/fast-food-outlets-physical-activity-facilities-and-obesity-among-adults-nationwide-longitudinal - 2025-01-07

Days absent from work as a result of complications associated with type 2 diabetes: Evidence from 20 years of linked national registry data in Sweden

Published 21 July 2020 A total of 413 000 people with T2D aged <66 years, comprising 4.9 million person‐years, was included. The crude proportion with any absence was higher among those with T2D compared to controls (47% vs. 26%) in the index year, and the median (IQR) number of days was higher (223 [77;359] vs. 196 [59;352]) if any absence. Regression analyses showed that complications per se wer

https://www.lupop.lu.se/article/days-absent-work-result-complications-associated-type-2-diabetes-evidence-20-years-linked-national - 2025-01-07

History of Previous Fracture and Imminent Fracture Risk in Swedish Women Aged 55 to 90 Years Presenting With a Fragility Fracture

Published 21 July 2020 The term “fracture cascade” refers to the sequence of fragility fractures resulting from the increased fracture risk that occurs with aging and following fractures. Here, we evaluate the sequence of previous fractures in women aged 55 to 90 years presenting with a fragility fracture and subsequent (12 to 24 months) fracture incidence. In this retrospective, observational stu

https://www.lupop.lu.se/article/history-previous-fracture-and-imminent-fracture-risk-swedish-women-aged-55-90-years-presenting - 2025-01-07

Agreement between area- and individual-level income measures in a population-based cohort: Implications for population health research

Published 22 July 2020 Socioeconomic status is an important determinant of health, the measurement of which is of great significance to population health research. However, individual-level socioeconomic factors are absent from much health administrative data, resulting in widespread use of area-level measures in their place. This study aims to clarify the role of individual- and area-level socioe

https://www.lupop.lu.se/article/agreement-between-area-and-individual-level-income-measures-population-based-cohort-implications - 2025-01-07

Adolescents living with HIV are at higher risk of death and loss to follow up from care: Analysis of cohort data from eight health facilities in Ethiopia

Published 22 July 2020 This was a retrospective cohort study carried out in eight health facilities in two regions of Ethiopia. Adolescents (age 10–14 and 15–19 year) and children (age 0–9 year) enrolled in chronic HIV care between 2005 and 2013 constituted the study population. We reviewed the individual patient charts between March and June 2014 and updated the data on the status of each patient

https://www.lupop.lu.se/article/adolescents-living-hiv-are-higher-risk-death-and-loss-follow-care-analysis-cohort-data-eight-health - 2025-01-07

Lipoprotein Particle Predictors of Arterial Stiffness after 17 Years of Follow Up: The Malmö Diet and Cancer Study

Published 23 July 2020 Central arterial stiffness is a surrogate of cardiovascular risk and predicts cardiovascular mortality. Apolipoprotein B lipoproteins are also established cardiovascular risk factors. It is not known whether specific lipoprotein subclasses measured in the Malmö Diet and Cancer Study and previously shown to be associated with coronary heart disease also predict arterial stiff

https://www.lupop.lu.se/article/lipoprotein-particle-predictors-arterial-stiffness-after-17-years-follow-malmo-diet-and-cancer-study - 2025-01-07

Using metabolite profiling to construct and validate a metabolite risk score for predicting future weight gain

Published 23 July 2020 Excess weight gain throughout adulthood can lead to adverse clinical outcomes and are influenced by complex factors that are difficult to measure in free-living individuals. Metabolite profiling offers an opportunity to systematically discover new predictors for weight gain that are relatively easy to measure compared to traditional approaches. New publication in PLOS ONE

https://www.lupop.lu.se/article/using-metabolite-profiling-construct-and-validate-metabolite-risk-score-predicting-future-weight - 2025-01-07

Daily School Physical Activity from before to after Puberty Improves Bone Mass and a Musculoskeletal Composite Risk Score for Fracture

Published 24 July 2020 This 7.5-year prospective controlled exercise intervention study assessed if daily school physical activity (PA), from before to after puberty, improved musculoskeletal traits. There were 63 boys and 34 girls in the intervention group (40 min PA/day), and 26 boys and 17 girls in the control group (60 min PA/week). We measured musculoskeletal traits at the start and end of th

https://www.lupop.lu.se/article/daily-school-physical-activity-after-puberty-improves-bone-mass-and-musculoskeletal-composite-risk - 2025-01-07

Diabetes mellitus as a risk factor for compression neuropathy: a longitudinal cohort study from southern Sweden

Published 24 July 2020 Compression neuropathies (CN) in the upper extremity, the most common being carpal tunnel syndrome (CTS) and ulnar nerve entrapment (UNE), are frequent among patients with diabetes mellitus (DM). Earlier studies have shown contradicting results regarding DM as a risk factor for CN. Thus, the aim of the present population-based, longitudinal study was to explore potential ass

https://www.lupop.lu.se/article/diabetes-mellitus-risk-factor-compression-neuropathy-longitudinal-cohort-study-southern-sweden - 2025-01-07

Injuries and illnesses in Swedish Paralympic athletes—A 52‐week prospective study of incidence and risk factors

Published 25 July 2020 Sports‐related injuries and illnesses in Paralympic sport (SRIIPS) are a concern, but knowledge about the etiology and risk factors is limited. The aim of this study was to describe the annual incidence, type, and severity of injuries and illnesses among Swedish Paralympic athletes and to assess risk factors. New publication in Scandinavian Journal of Medicine & Science in S

https://www.lupop.lu.se/article/injuries-and-illnesses-swedish-paralympic-athletes-52-week-prospective-study-incidence-and-risk - 2025-01-07

Changes in breast density over serial mammograms: A case-control study

Published 25 July 2020 In addition to a breast density category, temporal changes in breast density have gained attention as a dynamic breast cancer risk marker. This case-control study aimed to investigate a potential change in breast density preceding tumor development and the relationship of this potential change to prognostic pathological tumor variables. New publication in European Journal of

https://www.lupop.lu.se/article/changes-breast-density-over-serial-mammograms-case-control-study - 2025-01-07