Published 23 July 2020 Excess weight gain throughout adulthood can lead to adverse clinical outcomes and are influenced by complex factors that are difficult to measure in free-living individuals. Metabolite profiling offers an opportunity to systematically discover new predictors for weight gain that are relatively easy to measure compared to traditional approaches. New publication in PLOS ONE

https://www.lupop.lu.se/article/using-metabolite-profiling-construct-and-validate-metabolite-risk-score-predicting-future-weight - 2025-01-07

Published 24 July 2020 This 7.5-year prospective controlled exercise intervention study assessed if daily school physical activity (PA), from before to after puberty, improved musculoskeletal traits. There were 63 boys and 34 girls in the intervention group (40 min PA/day), and 26 boys and 17 girls in the control group (60 min PA/week). We measured musculoskeletal traits at the start and end of th

https://www.lupop.lu.se/article/daily-school-physical-activity-after-puberty-improves-bone-mass-and-musculoskeletal-composite-risk - 2025-01-07

Published 24 July 2020 Compression neuropathies (CN) in the upper extremity, the most common being carpal tunnel syndrome (CTS) and ulnar nerve entrapment (UNE), are frequent among patients with diabetes mellitus (DM). Earlier studies have shown contradicting results regarding DM as a risk factor for CN. Thus, the aim of the present population-based, longitudinal study was to explore potential ass

https://www.lupop.lu.se/article/diabetes-mellitus-risk-factor-compression-neuropathy-longitudinal-cohort-study-southern-sweden - 2025-01-07

Published 18 June 2020 You can now sign up for participation - in person or online - in Lund Population Day 2020: Healthy Aging. Read more here.

https://www.lupop.lu.se/article/registration-open-lund-population-day-2020 - 2025-01-07

Published 25 July 2020 Sports‐related injuries and illnesses in Paralympic sport (SRIIPS) are a concern, but knowledge about the etiology and risk factors is limited. The aim of this study was to describe the annual incidence, type, and severity of injuries and illnesses among Swedish Paralympic athletes and to assess risk factors. New publication in Scandinavian Journal of Medicine & Science in S

https://www.lupop.lu.se/article/injuries-and-illnesses-swedish-paralympic-athletes-52-week-prospective-study-incidence-and-risk - 2025-01-07

Published 25 July 2020 In addition to a breast density category, temporal changes in breast density have gained attention as a dynamic breast cancer risk marker. This case-control study aimed to investigate a potential change in breast density preceding tumor development and the relationship of this potential change to prognostic pathological tumor variables. New publication in European Journal of

https://www.lupop.lu.se/article/changes-breast-density-over-serial-mammograms-case-control-study - 2025-01-07

Published 26 July 2020 A total of 37 items operationalizing participation were administered via a questionnaire to 364 next of kin of older people in nursing homes. Measurement properties were tested with factor analysis and Rasch model analysis. New publication in PLOS ONE

https://www.lupop.lu.se/article/measuring-next-kins-experience-participation-care-older-people-nursing-homes - 2025-01-07

Published 26 July 2020 In Sub-Saharan Africa, being overweight in childhood is rapidly rising while stunting is still remaining at unacceptable levels. A key contributor to this double burden of malnutrition is dietary changes associated with nutrition transition. Although the importance of socio-economic drivers is known, there is limited knowledge about their stratification and relative importan

https://www.lupop.lu.se/article/social-stratification-diet-diversity-and-malnutrition-among-preschoolers-survey-addis-ababa-ethiopia - 2025-01-07

Published 27 July 2020 Clinical practice improvements based on quality-register data are influenced by multiple factors. Although there is agreement that information from quality registers is valuable for quality improvement, practical ways of organising register use have been notoriously difficult to realise. The present study sought to investigate the mechanisms that lead various clinicians to u

https://www.lupop.lu.se/article/role-professional-logics-quality-register-use-realist-evaluation-0 - 2025-01-07

Published 27 July 2020 Sun exposure in combination with skin pigmentation is the main determinant for vitamin D status. Human skin color seems to be adapted and optimized for regional sun ultraviolet (UV) intensity. However, we do not know if fair, UV-sensitive skin is a survival advantage in regions with low UV radiation. New publication in PLOS ONE

https://www.lupop.lu.se/article/women-fair-phenotypes-seem-confer-survival-advantage-low-uv-milieu-nested-matched-case-control-study - 2025-01-07

Published 28 July 2020 Spatial epidemiological analyses primarily depend on spatially-indexed medical records. Some countries have devised ways of capturing patient-specific spatial details using ZIP codes, postcodes or personal numbers, which are geocoded. However, for most resource-constrained African countries, the absence of a means to capture patient resident location as well as inexistence o

https://www.lupop.lu.se/article/establishing-spatially-enabled-health-registry-systems-using-implicit-spatial-data-pools-case-study-0 - 2025-01-07

Published 28 July 2020 Analyses were based on Swedish case–control data comprising incident cases of LADA (n = 465) and T2D (n = 1528) with matched, population-based controls (n = 1789; n = 1553 in genetic analyses). Multivariable-adjusted ORs in relation to self-reported processed and unprocessed red meat intake were estimated by conditional logistic regression models. Attributable proportion (AP

https://www.lupop.lu.se/article/consumption-red-meat-genetic-susceptibility-and-risk-lada-and-type-2-diabetes - 2025-01-07

Published 29 July 2020 The authors assessed the effect of incorporating the timing of cancer diagnosis events into the assessment of familial risks of breast cancer in first‐degree and second‐degree relatives in a nationwide cohort study of 5,099,172 women (follow‐up was between 1958‐2015). Family history was assessed using 3 approaches: 1) as a static variable (ever having a relative with breast

https://www.lupop.lu.se/article/familial-risk-breast-cancer-dynamic-accumulative-and-static-definitions-family-history - 2025-01-07

Published 29 July 2020 Ulnar nerve entrapment at the elbow (UNE) is overrepresented in patients with diabetes, but the outcome of surgery is unknown. We aimed to evaluate patient-reported outcome in patients with and without diabetes, and to assess potential sex differences and compare surgical treatment methods. Data on patients operated for UNE (2010-2016, n = 1354) from the Swedish National Reg

https://www.lupop.lu.se/article/ulnar-nerve-entrapment-diabetes-patient-reported-outcome-after-surgery-national-quality-registries - 2025-01-07

Published 28 July 2020 Nyhetsbrev från Svensk nationell datatjänst juni 2020. Läs mer här.

https://www.lupop.lu.se/article/snd-natverksnytt-0 - 2025-01-07

By noomi [dot] egan [at] fsi [dot] lu [dot] se (Noomi Egan) - published 18 November 2024 Johan Flygare and the remarkable story of the genesis of Apriligen, a company which aims to find a cure for the rare blood disease, Diamond–Blackfan Anemia, DBA. Photo: Johan Persson. After 20 years of research on gene therapy and the rare blood disease, Diamond-Blackfan Anemia, DBA, researcher Johan Flygare h

https://www.medicine.lu.se/article/science-start-developing-gene-therapy-rare-blood-disorder - 2025-01-07

Published 22 November 2024 In a study published in Advanced Science, researcher Fredrik Ek et al. describe how they can use light to create electrically conductive materials directly in the body, showing promising results in animal trials. Photo: I. Hultquist. Bioelectronics research and development of implants made of electrically conductive materials for disease treatment is advancing rapidly. H

https://www.medicine.lu.se/article/using-light-create-bioelectronics-inside-body - 2025-01-07

By tove [dot] smeds [at] med [dot] lu [dot] se (Tove Smeds) - published 25 November 2024 Kristian Riesbeck, professor of clinical bacteriology at Lund University. Photo: Tove Smeds It has been a year ago since bacteria from war-wounded at hospitals in Ukraine were analysed. The study, which attracted a lot of attention, showed that some of the bacteria types had total resistance to antibiotics. No

https://www.medicine.lu.se/article/pandrug-resistant-bacteria-war-ukraine-are-extremely-pathogenic - 2025-01-07

By tove [dot] smeds [at] med [dot] lu [dot] se (Tove Smeds) - published 3 December 2024 Magnesium plays a crucial role in protecting cells against damage from free radicals (antioxidant defense). Illustration: iStock/Just_Super An international team of researchers, led by scientists at Lund University, has uncovered how magnesium enters mitochondria. Magnesium is a vital mineral that plays a key r

https://www.medicine.lu.se/article/auto-regulating-channels-supply-our-cells-magnesium - 2025-01-07

By alexis_bento [dot] luis [at] med [dot] lu [dot] se (Alexis Luis Bento) - published 5 December 2024 "This collaboration is truly valuable and with high potential because it merges clinical, molecular, and computational expertise,” states Johan Jakobsson. Photo: iStock/Vitalii Gulenok A team of international researchers led by Professor Johan Jakobsson at Lund University has secured a 52 million

https://www.medicine.lu.se/article/52-million-sek-goes-uncovering-genetic-drivers-parkinsons-disease-0 - 2025-01-07