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FRA as a meeting place of law and social sciences
This chapter describes the process of the ‘law looking outwards’, and the gradual rapprochement that has taken place between the law and social sciences. This has occurred in many spheres of law, but is relatively new to the human rights sphere. Meanwhile, it has become a major characteristic of FRA’s approach. The authors assert that there are at least four ways in which this approach can add val
Combining semilocal exchange with dynamical mean-field theory : Electronic structure and optical response of rare-earth sesquioxides
In rare-earth semiconductors, wide ligand p and rare-earth 5d bands coexist with localized, partially filled 4f shells. A simultaneous description for both extended and localized states represents a significant challenge for first-principles theories. Here, we combine an ab initio dynamical mean-field theory approach to strong local correlations with a perturbative application of the semilocal mod
Human genes for the alpha and beta chains of complement C4b-binding protein are closely linked in a head-to-tail arrangement
C4b-binding protein (C4BP) is an important component in the regulation of the complement system and also binds the anticoagulant vitamin K-dependent protein S. These activities are performed by distinct, although structurally related, polypeptides of 70 kDa (alpha chain) and 45 kDa (beta chain), respectively. In this report we have investigated the genetic relationships between these polypeptides.
Protein S binding in relation to the subunit composition of human C4b-binding protein
The human regulatory complement component C4b-binding protein (C4BP) circulates in plasma either as a free protein or in a bimolecular complex with the vitamin K-dependent protein S. The major form of C4BP is composed of 7 identical, disulfide-linked 70 kDa subunits (alpha-chains), the arrangement of which gives the C4BP molecule a spider-like appearance. Recently, we identified a unique 45 kDa su
Novel subunit in C4b-binding protein required for protein S binding
C4b-binding protein (C4BP) is a multimeric protein with regulatory functions in the complement system. It also interacts with vitamin K-dependent protein S, which is involved in the regulation of the coagulation system. It has been demonstrated that C4BP consists of seven disulfide-linked, identical 70-kDa subunits, which are arranged to give the molecule a spider-like structure. We now have evide
The Sixteenth International Conference on Surface X-Ray and Neutron Scattering (SXNS16)
The HIV-1 epidemic in Ethiopia – transmission patterns, antiretroviral drug resistance and treatment outcomes
A comprehensive understanding of local HIV epidemiology is essential for monitoring transmission, designing, implementing, and evaluating HIV intervention strategies. In paper I, we used a total of 1276 HIV-1 subtype C pol sequences and employed state-of-art phylogenetic and phylodynamic tools to describe the molecular epidemiology of HIV in Ethiopia. Our results showed that the HIV epidemic in Et
Effects of pre-injection on ignition, combustion and emissions of spray under engine-like conditions
Large-eddy simulation (LES) of multiple-injection spray combustion under engine-like conditions is performed using a coupled model of an Eulerian stochastic field transported probability density function (ESF T-PDF) and a flamelet generated manifold (FGM). This coupled model allows the use of the T-PDF methods in modeling the interaction of turbulence and chemistry at affordable computational cost
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Design of a high-resolution Rayleigh-Taylor experiment with the Crystal Backlighter Imager on the National Ignition Facility
The Rayleigh-Taylor (RT) instability affects a vast range of High Energy Density (HED) length scales, spanning from supernova explosions (1013 m) to inertial confinement fusion (10-6 m). In inertial confinement fusion, the RT instability is known to induce mixing or turbulent transition, which in turn cools the hot spot and hinders ignition. The fine-scale features of the RT instability, which are
Activated protein C resistance and anticoagulant proteins in young adults with central retinal vein occlusion
BACKGROUND: Central retinal vein occlusion is a disease that is most common in old people, and often associated with atherosclerosis, hypertension, diabetes or glaucoma. Since these diseases are much less evident in young people, we wanted to investigate the prevalence of disorders in the most common anticoagulant proteins in a group of young patients with central retinal vein occlusion.METHODS: 3
A Key-Recovery Side-Channel Attack on Classic McEliece Implementations
In this paper, we propose the first key-recovery side-channel attack on Classic McEliece, a KEM finalist in the NIST Post-quantum Cryptography Standardization Project. Our novel idea is to design an attack algorithm where we submit special ciphertexts to the decryption oracle that correspond to cases of single errors. Decoding of such ciphertexts involves only a single entry in a large secret perm
Modeling and simulating the sample complexity of solving LWE using BKW-style algorithms
The Learning with Errors (LWE) problem receives much attention in cryptography, mainly due to its fundamental significance in post-quantum cryptography. Among its solving algorithms, the Blum-Kalai-Wasserman (BKW) algorithm, originally proposed for solving the Learning Parity with Noise (LPN) problem, performs well, especially for certain parameter settings with cryptographic importance. The BKW a
Preferences for redistribution
We survey the literature on preferences for redistribution. We discuss different ways the literature has measured these preferences and review literature on the different determinants of preferences for redistribution. These range from institutions and demographic factors to fairness views and social preferences. Income inequality is, perhaps unsurprisingly, one of the most important determinants
Which architectural style makes an attractive streetscape? Aesthetic preferences among city centre managers
Rational design based on aesthetic principles from the 1930s dominates contemporary architecture and property development, contributing to a homogenous urban landscape. The aim of this paper is to examine how professionals involved in city centre development value different architectural styles. Based on a sample of 109 respondents, measuring the architectural preferences of city centre managers,
The influence of personal and public health and smart applications on biking behavior in South Korea
Bicycling is an important form of active transport that contributes to sustainability mobility as a result of its role in personal and public health and emissions reduction. The significance of which has grown since the COVID-19 pandemic outbreak. However, biking studies have neglected, in theoretical terms, developing an understanding of why consumers bike. Therefore, this research designs and ve
Transgressing purity: Intersectional negotiations of gender identity in Swedish schools
The vulnerability of gender nonconforming young people is all too well documented. Arguably, “trans issues” in schools are not restricted to transphobic comments, and need to be analyzed intersectionally. Guided by Lugones’ discussion of the politics of purity read together with the analysis of cisnormativity, this article draws on interviews with Rakel, Robin and Mika, who were part of a larger s
Accomplishing Cultural Policy in Europe: Financing, Governance and Responsiveness
This book investigates the activities undertaken by the variety of actors that contribute to accomplishing cultural policy in Europe. These range from policy formulation and administration at the national and local levels, to artistic and cultural production activities to institutional governance.