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Cadmium exposure and coronary artery atherosclerosis : A cross-sectional population-based study of swedish middle-aged adults

BACKGROUND: The general population is ubiquitously exposed to the toxic metal cadmium through the diet and smoking. Cadmium exposure is associated with increased morbidity and mortality in myocardial infarction and stroke. Atherosclerosis is the main underlying mechanism of myocardial infarction. However, associations between cadmium and coronary artery atherosclerosis have not been examined. OBJE

Rhythmic behaviors in chimpanzees : Range, functional contexts, sex differences and emotional correlates

There have been recently multiple calls to investigate the rhythmic behaviors (RBs) of nonhuman animals, as a way to gain insight into the evolution of human rhythm cognition and musicality. Currently, the empirical data from non-human species is scarce. Most strikingly, we lack data from chimpanzees (Pan troglodytes), our closest genetic relatives. Here, we present an observational study conducte

Use of faba bean (Vicia faba L.) hulls as substrate for Pleurotus ostreatus – Potential for combined mushroom and feed production

A circular concept involving use of faba bean hulls for production of oyster mushrooms (Pleurotus ostreatus (Jacq.) P. Kumm.) and the post-harvest residues for feed purposes was evaluated. Faba bean hulls are a waste remaining after the beans are dehulled to decrease the content of anti-nutritional factors and increase the food value of the beans. Faba bean hulls proved very suitable as substrate

Accuracy of 1-Hour Plasma Glucose During the Oral Glucose Tolerance Test in Diagnosis of Type 2 Diabetes in Adults : A Meta-analysis

OBJECTIVE: One-hour plasma glucose (1-h PG) during the oral glucose tolerance test (OGTT) is an accurate predictor of type 2 diabetes. We performed a meta-analysis to determine the optimum cutoff of 1-h PG for detection of type 2 diabetes using 2-h PG as the gold standard. RESEARCH DESIGN AND METHODS: We included 15 studies with 35,551 participants from multiple ethnic groups (53.8% Caucasian) and

Distinct patterns of dyskinetic and dystonic features following D1 or D2 receptor stimulation in a mouse model of parkinsonism

L-DOPA-induced dyskinesia (LID) is a significant complication of dopamine replacement therapy in Parkinson's disease (PD), and the specific role of different dopamine receptors in this disorder is poorly understood. We set out to compare patterns of dyskinetic behaviours induced by the systemic administration of L-DOPA and D1 or D2 receptor (D1R, D2R) agonists in mice with unilateral 6-hydroxydopa

Kidney protection with the radical scavenger α1-microglobulin (A1m) during peptide receptor radionuclide and radioligand therapy

α1-microglobulin (A1M) is an antioxidant found in all vertebrates, including humans. It has enzymatic reductase activity and can scavenge radicals and bind free heme groups. Infused recombinant A1M accumulates in the kidneys and has therefore been successful in protecting kidney injuries in different animal models. In this review, we focus on A1M as a radioprotector of the kidneys during peptide r

The Atlantic Walrus : Multidisciplinary Insights into Human-Animal Interactions

The Atlantic Walrus: Multidisciplinary insights into human-animal interactions addresses the key dimensions of long-term human walrus interactions across the Atlantic Arctic and subarctic regions, over the past millennia. This book brings together research from across the social and natural sciences to explore walrus biology, human culture, environmental conditions and their reciprocal effects. To

Pre- and Postoperative Circulating IGF-I, IGFBP-3, and IGFBP-7 Levels in Relation to Endocrine Treatment and Breast Cancer Recurrence : A Nested Case-Control Study

Insulin-like growth factor-I (IGF-I) and its binding proteins (BPs) have been associated with breast cancer risk, especially high IGF-I concentrations and the biologically active fraction estimated as the IGF-I/IGFBP-3 molar ratio. The relation of circulating IGF-I and IGFBP-3 concentrations with risk of breast cancer recurrence has been less documented. In addition a new member to a sub-group of

Ab initio modelling of intergranular fracture of nickel containing phosphorus: Interfacial excess properties

In the present work, the impact of phosphorus impurities on the grain boundary strength of nickel has been investigated by means of density functional theory (DFT) modelling. Owing to different outcomes and trends previously reported in the literature, it is unclear whether P is strengthening or weakening the Ni grain boundary. To address this issue, we utilize three different DFT based methods: t

Numerical analysis of infraspecific variation in European Silene alba and S. dioica (Caryophyllaceae)

Infraspecific variation among European populations of Silene alba and S. dioica was analysed by non‐metric multidimensional scaling, which was applied to K‐dissimilarity matrices based either on 16 seed characters or on 34 seed, flower and capsule characters. The material used for analysis consisted of 167 collections of wild seed, largely obtained from European botanic gardens, and 97 sets of mat

European Resuscitation Council and European Society of Intensive Care Medicine Guidelines 2021 : Post-resuscitation care

The European Resuscitation Council (ERC) and the European Society of Intensive Care Medicine (ESICM) have collaborated to produce these post-resuscitation care guidelines for adults, which are based on the 2020 International Consensus on Cardiopulmonary Resuscitation Science with Treatment Recommendations. The topics covered include the post-cardiac arrest syndrome, diagnosis of cause of cardiac a

Challenges with Security Force Assistance in Niger: Understanding Local Context and Aligning Interests

Since the attacks the 11th of September 2001 in the US, there has been a strong increase in security force assistance (SFA) to fragile states with the aim of professionalising security forces, preventing violent extremist organisations (VEO) from exploiting state fragility and, in cases where this has not succeeded, of fighting the latter. At the same time, a shift has taken place with regard to t