BACKGROUND: A distinctive feature of type 2 diabetes is inability of insulin-secreting beta-cells to properly respond to elevated glucose eventually leading to beta-cell failure. We have hypothesized that an abnormally increased NO production in the pancreatic islets might be an important factor in the pathogenesis of beta-cell dysfunction. PRINCIPAL FINDINGS: We show now that islets of type 2 spo

In dense passive radio frequency identification (RFID) systems, code division multiple access (CDMA) techniques can be used to alleviate severe collisions and thus enhance the system performance. However, conventional CDMA techniques are challenging to implement, especially for passive tags due to cost and power constraints. In this paper, we design a CDMA-based multi-reader passive ultra high fre

The aim of the study was to investigate functional ability and health complaints of people, 65+, living in special accommodation (equivalent to nursing home) and their counterparts who live at home and receive municipal care or a combination of municipal and informal care. Persons (n = 1958) receiving municipal care were assessed in terms of functional ability, health complaints, and level of info

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Purpose To assess the natural history of intrameniscal signal intensity on magnetic resonance (MR) images of the medial compartment. Materials and Methods Both knees of 269 participants (55% women, aged 45-55 years) in the Osteoarthritis Initiative without radiographic knee osteoarthritis (OA) and without medial meniscal tear at baseline were studied. One radiologist assessed 3-T MR images from ba

This paper studies three different strategies of sourcing. The whole process of this research including the problem definition is exactly based on a real case condition. This paper model sourcing process of required parts and material for a product which is manufactured under the license of Peugeot Company, the mother manufacturer in France. Based on the agreement between Peugeot and the manufactu

The nation is born out of the resistance, ideally without external aid, of its nascent citizens against oppression [...] An effective founding struggle should contain memorable massacres, atrocities, assassinations and the like, which serve to unite and strengthen resistance and render the resulting victory the more justified and the more fulfilling. They also can provide a focus for a "remember t

The paper focuses on the transformation of the industrial structure and the location dynamics on the edge of the metropolitan region of Copenhagen with the aim of explaining the rise of new spaces in the urban economic geography. The main concern of the paper is the role the transformation of the outer city plays in the urban economy of Copenhagen. The centre of attention is on the changing indust

Det finns ett myller av sammanflätade tilldragelser som man skulle kunna ta fasta på för att förstå uppkomsten av den globala rättviserörelsen. Det är fråga om ett myller som i och med demonstrationerna i Seattle, Prag, Göteborg, Genua och den globala fredsdemonstrationen den 15 februari 2003, de sociala världsforumen i Porto Alegre och Mumbai och ett otal andra aktiviteter inte går att förstå som

Microinvasion is the smallest morphologically identifiable stage of invasion. Its presence and distinction from in situ carcinoma may have therapeutic implications, and clinical staging also requires the recognition of this phenomenon. Microinvasion is established on the basis of several morphological criteria, which may be difficult and not perfectly reproducible among pathologists. The aim of th

Application-specific circuits are used to migrate computer systems from workstations to handheld devices that need real-time performance within the budget for physical size and energy dissipation. However, these circuits are inflexible as any modification requires redesign and refabrication, which is both expensive and time-consuming considering the complexity of recent embedded platforms. Therefo