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Background: Amyloidosis represents a rare yet heterogeneous multi-system disorder associated with a grave prognosis and an enormous psycho-emotional strain on patients, relatives, and caregivers. We here present the overall study design and first results of AMY-NEEDS, a research program aiming to systematically assess the needs of patients suffering from amyloidosis, their relatives and health car

YOU ARE A DAY TOMORROW – THE CLASSROOM AS BATTLEFIELDYou Are a Day Tomorrow, a spatial audio play, experienced in a classroom. It is a memoir tying past and present, a personal narrative exploring the social dynamics of school and the institutional influence on the body and soul. It presents an auditory sensitivity analysis that examines nostalgia and brutality. You Are a Day Tomorrow is an invita

BACKGROUND: Anastomotic leakage after anterior resection for rectal cancer is more common after total mesorectal excision compared to partial mesorectal excision but might be mitigated by a defunctioning stoma. OBJECTIVE: The aim is to assess how anastomotic leakage is affected by type of mesorectal excision and defunctioning stoma use. DESIGN: This is a retrospective multicenter cohort study eval

Understanding human behaviour in fires (HBiF), whether in building or wildland fire contexts, is crucial for saving lives and managing evacuations. However, existing research lacks a comprehensive analysis of HBiF knowledge from both perspectives. To address this issue, we examined nearly 1900 HBiF-related research papers and their references, identifying around 6600 frequently cited references as

Teacher education for upper secondary school in Sweden is mainly university-based but with parts of the studies as school-based courses. To tackle the main obstacles to pre-service teachers’ placements, and to strengthen collaboration regarding quality and collaborative research, a new national policy is being implemented, which changes the prerequisites for collaboration between schools and unive

Methane (CH4) emissions from manure management on livestock farms are a key source of greenhouse gas emissions in some regions and for some production systems, and the opportunities for mitigation may be significant if emissions can be adequately documented. We investigated a method for estimating CH4 emissions from liquid manure (slurry) that is based on anaerobic incubation of slurry collected f

With several upcoming sample return missions, such as the Mars Sample Return Campaign, non-destructive methods will be key to maximizing their scientific output. In this study, we demonstrate that the combination of neutron and X-ray tomography provides an important tool for the characterization of such valuable samples. These methods allow quantitative analyses of internal sample features and als

Electron effective mass is a fundamental material parameter defining the free charge carrier transport properties, but it is very challenging to be experimentally determined at high temperatures relevant to device operation. In this work, we obtain the electron effective mass parameters in a Si-doped GaN bulk substrate and epitaxial layers from terahertz (THz) and mid-infrared (MIR) optical Hall e

Due to the small characteristic molecular size of hydrogen, small leaks are more common in hydrogen systems compared to similar systems with hydrocarbons. This, together with the high reactivity, makes an efficient ventilation system very important in hydrogen applications. There are several models available for ventilation sizing that are based on either a well-mixed assumption or a fully stratifDue to the small characteristic molecular size of hydrogen, small leaks are more common in hydrogen systems compared to similar systems with hydrocarbons. This, together with the high reactivity, makes an efficient ventilation system very important in hydrogen applications. There are several models available for ventilation sizing that are based on either a well-mixed assumption or a fully stratif

During the last 10 years or so the Brownian shape-motion (BSM) model has been used in numerous calculations of fission-fragment mass and charge distributions with encouraging agreement with experimental measurements. In this model the structure obtained in the fission-fragment distributions is entirely a consequence of the structures in the calculated five-dimensional (5D) potential-energy surface

Background: Obsessive-compulsive disorder (OCD) has been associated with a broad range of health-related issues. Unhealthy lifestyle habits such as physical inactivity, an unhealthy diet, smoking, and alcohol consumption are hypothesized to contribute to this association. However, the lifestyle habits of individuals with OCD have been scarcely investigated. In this international survey, we explore

Metabolic reprogramming is critical during clear cell renal cell carcinoma (ccRCC) tumorigenesis, manifested by accumulation of lipid droplets (LDs), organelles that have emerged as new hallmarks of cancer. Yet, regulation of their biogenesis is still poorly understood. Here, we demonstrate that MYC inhibition in ccRCC cells lacking the von Hippel Lindau (VHL) gene leads to increased triglyceride

The production of the ψ(2S) charmonium state was measured with ALICE in Pb-Pb collisions at √sNN=5.02 TeV, in the dimuon decay channel. A significant signal was observed for the first time at LHC energies down to zero transverse momentum, at forward rapidity (2.5

The first measurements of K∗(892)0 resonance production as a function of charged-particle multiplicity in Xe-Xe collisions at sNN=5.44 TeV and pp collisions ats=5.02 TeV using the ALICE detector are presented. The resonance is reconstructed at midrapidity (|y| < 0.5) using the hadronic decay channel K∗0 →K±π∓. Measurements of transverse-momentum integrated yield, mean transverse-momentum, nuclear

Background: Pesticide exposure may affect young children's neurodevelopment, but only few cohort studies have addressed possible effects of non-organophosphate pesticides. Objective: We evaluated associations between prenatal current-use pesticide exposure and neurodevelopmental outcomes among 1-year-old children from the Infants’ Environmental Health (ISA) birth cohort. Methods: To determine pren

The inclusive top-quark-pair production cross section σtt¯ and its ratio to the Z-boson production cross section have been measured in proton–proton collisions at s=13.6 TeV, using 29 fb−1 of data collected in 2022 with the ATLAS experiment at the Large Hadron Collider. Using events with an opposite-charge electron-muon pair and b-tagged jets, and assuming Standard Model decays, the top-quark-pair

On December 5, 2022, an indirect drive fusion implosion on the National Ignition Facility (NIF) achieved a target gain Gtarget of 1.5. This is the first laboratory demonstration of exceeding "scientific breakeven"(or Gtarget>1) where 2.05 MJ of 351 nm laser light produced 3.1 MJ of total fusion yield, a result which significantly exceeds the Lawson criterion for fusion ignition as reported in a pr