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In the present study, wild type and three mutants of pyranose 2-oxidase (PyOx-WT, PyOx-MT1, PyOx-MT2, PyOx-MT3), which showed improved properties for D-galactose oxidation, were investigated for their oxidising ability when immobilised on graphite electrodes. Four different flexible Os polymers with formal potentials ranging between −0.140 and 0.270 V vs. Ag|AgCl0.1 M KCl were applied together wit
We present evidence of a submerged early Holocene landscape off the Blekinge coastline in the Baltic Sea, dating to the Yoldia Sea and Initial Littorina Sea Stages when the water level was lower than at present. 14C dated wood remains obtained by surveillance diving and new archaeological findings in combination with bathymetric analyses and interpolations between other sites across the Baltic Sea
Background: The naturally occurring male-to-female (M/F) ratio at birth is 1.05. Higher ratios found primarily in countries across Asia have been attributed to prenatal sex selection due to son preference. There is growing evidence that sex-selective practices continue following migration; however, little is known about these practices following migration to Australia.Methods: In this population-b
The study aim was to explore the relationship between a developmental assessment at preschool age and an intelligence quotient (IQ) assessment at school age. One hundred sixty-two children were assessed at 2.5 years with the Bayley Scales of Infant and Toddler Development—Third Edition (Bayley-III) and then at 6.5 years with the Wechsler Intelligence Scale for Children—Fourth Edition (WISC-IV). Th
This chapter expresses that autism spectrum disorder (ASD) is a heterogeneous disorder where several neural networks are involved in producing the behavioral symptoms. Comorbidity in other neurodevelopmental and psychiatric disorders is a hallmark of ASD. The chapter presents an overview of the clinical and neurobiological characteristics of ASD as well as the literature on the association between
Background: 4D-flow magnetic resonance imaging (MRI) is increasingly used. Purpose: To validate 4D-flow sequences in phantom and in vivo, comparing volume flow and kinetic energy (KE) head-to-head, with and without respiratory gating. Material and Methods: Achieva dStream (Philips Healthcare) and MAGNETOM Aera (Siemens Healthcare) 1.5-T scanners were used. Phantom validation measured pulsatile, th
Background: Ventriculitis is a serious complication when using external ventricular drains (EVDs). Bactericidal silver coating has been reported to reduce risk of infection. In the clinical setting, the diagnosis is often made based on symptoms and analyses of cerebrospinal fluid, with treatment initiated before infection is verified by culture. The bactericidal effect might not correlate with a r
We studied the biomarker patterns related to axonal injury, astrogliosis and amyloid metabolism in cerebrospinal fluid (CSF) of children and adolescents with mitochondrial encephalopathy and identified correlations with phenotype and survival outcome. Forty-six pediatric patients with genetically verified mitochondrial encephalopathy and twenty-two controls investigated at the Queen Silvia Childre
Introduction: The Housing Enabler instrument, designed to measure housing accessibility, has not been used in samples with long-standing spinal cord injury. We aimed to investigate potential threats to the reliability and validity of the instrument when used among older adults with spinal cord injury. Method: Cross-sectional data from the Swedish Aging with Spinal Cord Injury Study (N = 123, injur
The global sensitivity analysis is an effective method to assess the performance of a chemical reaction mechanism. In the present study, the uncertainty analysis and the global sensitivity analysis of a detailed chemical mechanism of n-heptane are first performed based on the Monte Carlo method. The source of the prediction uncertainties of the C0-C7 sub-mechanisms and the reaction classes in the
A popular strategy for meeting over-determination and pre-emption challenges to the comparative counterfactual conception of harm is Derek Parfit’s suggestion, more recently defended by Neil Feit, that a plurality of events harms A if and only if that plurality is the smallest plurality of events such that, if none of them had occurred, A would have been better off. This analysis of ‘harm’ rests o
