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OBJECTIVE: Thyroid hormones control a variety of processes in the central nervous system and influence its response to different stimuli, such as ischemic stroke. Post-stroke administration of 3,3',5-triiodo-L-thyronine (T3) has been reported to substantially improve outcomes, but the optimal dosage and time window remain elusive.METHODS: Stroke was induced in mice by transient middle cerebral art

BACKGROUND: The discrepancy between experimental research and clinical trial outcomes is a persistent challenge in preclinical studies, particularly in stroke research. A possible factor contributing to this issue is the lack of standardization across experimental stroke models, leading to poor reproducibility in multicenter studies. This study addresses this gap by aiming to enhance reproducibili

År 2023 var 18 800 barn placerade i familjehem. Gemensamt för dessa barn är att de under en tid upphör att dela vardag med sin ursprungsfamilj. Att i en sådan situation upprätthålla relationen till föräldrarna innehåller en rad utmaningar. I kapitlet har vi belyst dessa utmaningar utifrån följande perspektiv: lagstiftning, teorier och erfarenheter från placerade barn, föräldrar, familjehemsföräldr

BackgroundAchieving safe and stable placements is a key mission for the foster care system. Foster parents and social workers are part of a caregiving network with responsibility for the child and their wellbeing. Emotionally dysregulated children's behaviors may pose a challenge to the caregiving system. Trauma-informed care (TIC) interventions aim at enhancing caregivers' understanding of such b

In architecture and urban geography, discussions on repair, maintenance and adap5ve re-usehave emerged as a crucial intellectual terrain. Temporal aspects of how the urban fabric isused have also emerged as an issue worth theore5cal and empirical a=en5on. Latching ontothese themes, we will present work tracking the history of conten5on around the publiclyowned mee5ng and arts venue in Lund’s Peopl

Despite years of encouraging translational research, ischemic stroke still remains as one of the highest unmet medical needs nowadays, causing a tremendous burden to health care systems worldwide. Following an ischemic insult, a complex signaling pathway emerges leading to highly interconnected thrombotic as well as neuroinflammatory signatures, the so-called thromboinflammatory cascade. Here, we

Objectives: To assess the existence of international, scientifically validated methods for manual surgical skills training and assessment. The aim was to create a descriptive chronological summary of the existing evidence and conclusions in the included articles. Methods: PubMed and Scopus were searched twice for reviews published between 1997 and October 2023 and between 1997 and January 2024. Th

Background: Parents’ perceptions of children’s sleep problems when using a weighted blanket could enhance the understanding of challenges faced by families with ADHD and sleep problems. This is in alignment with a client-centred approach. Acknowledging, what parents perceive as a problem in a family context. Aim: To explore changes in parents’ perceptions of their children’s sleep problems before

Urbanization in coastal megacities leads to trade-offs between development and ecology, degrading carbon sinks and disrupting spatial-functional balance. Current models often fail to integrate land use, carbon dynamics, and ecological zoning. This study created a system that brings together Patch-generating Land Use Simulation (PLUS), Integrated Valuation of Ecosystem Services and Trade-offs (InVE

By 2050, electric vehicles (EVs) are expected to be 40% of all cars on the road1. In some countries like Norway, more than 90% of the new cars sold are electric2. This rise in EVs presents challenges to the current electricity infrastructure to meet this rapid increase in electricity demand. In this study, we simulate urban residential electricity demand using an agent-based model to investigate t

Objective: Foetal growth restriction (FGR) affects 10% of pregnancies, contributing to 30% of stillbirths. Current management of early-onset FGR (< 32 + 0 weeks' gestation) delivers the foetus before stillbirth or irreversible organ damage. The resulting preterm births create additional risks independent of FGR. We determined the economic cost associated with severe early-onset FGR. Design: Econom

Observational studies suggest that direct contact from healthcare to at-risk relatives may increase genetic counselling (GC) uptake as compared to family-mediated risk disclosure, but randomised controlled trials (RCTs) are lacking. This study assessed whether the offer of direct letters to relatives at risk of hereditary breast and ovarian cancer (HBOC) or Lynch syndrome increases GC uptake compa

Hard turning offers a cost-effective alternative to traditional grinding, yet the tool wear progression limits the broader industrial adoption. During hard turning, the surface microstructure of AISI 52100 steel transforms into a nanocrystalline structure known as white layer, accompanied by significant surface residual stresses. With optimal cutting conditions, surfaces develop nanocrystalline mi

Aims: The main aim of the present study was to identify factors influencing health-related quality of life (HRQoL), as measured by EQ-5D-5L, in individuals 1 year after the acute phase of COVID-19.Methods: This cross-sectional study included 75 participants (51% females), 1 year after confirmed SARS-CoV-2 infection (76% hospitalised). Associations between HRQoL, measured by patient-reported outcom

Background: Subgroups of adult-onset diabetes, namely severe autoimmune diabetes (SAID), severe insulin-deficient diabetes (SIDD), severe insulin-resistant diabetes (SIRD), and mild obesity-related diabetes (MOD) or mild age-related (MARD) diabetes, have been defined with clinical variables and a machine-learning approach. Our aim was to describe their long-term outcomes and mortality. Methods: In

"Transformative Encounters" is a podcast series dedicated to the exploration and unpacking the concept "performative encounters" within the realm of contemporary performance and how it can be understood. This series forms an integral part of the knowledge dissemination deriving from the artistic research project How Little is Enough? that is centered on sustainability and social change, conducted

AnthroPod - the podcast of the Society for Cultural Anthropology