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An assembly factor promotes assembly of flavinated SDH1 into the succinate dehydrogenase complex

Succinate dehydrogenase (Complex II; SDH) plays an important role in mitochondrial respiratory metabolism. The SDH complex consists of four core subunits and multiple cofactors, which must be assembled correctly to ensure enzyme function. To date, only an assembly factor (SDHAF2) required for FAD insertion into subunit SDH1 has been identified in plants. Here, we report the identification of Arabi

Arsenite methyltransferase (AS3MT) polymorphisms and arsenic methylation in children in rural Bangladesh

BACKGROUND: Arsenic methylation efficiency, a susceptibility factor for arsenic toxicity, is in adults partly explained by variation in arsenite methyltransferase (AS3MT) gene. Little is known about the role of AS3MT for children's arsenic methylation.OBJECTIVES: Evaluating associations between AS3MT polymorphisms and children's arsenic methylation efficiency.METHODS: Bangladeshi children's arseni

Soft tissue sarcoma should be treated at a tumor center : A comparison of quality of surgery in 375 patients

We analyzed the quality of surgery In a population-based series of 375 patients with primary soft tissue sarcoma of the extremity (n 329) and trunk wall (n 46). the quality was measured as the total number of operations performed for the primary tumor-biopsy, excision, reexcision-and the local recurrence rate. A comparison was made between patients referred to our tumor center before surgery (n 19

Limb-sparing surgery without radiotherapy based on anatomic location of soft tissue sarcoma

From 1980 through 1986, 119 patients with soft tissue sarcomas of the extremities were referred to our tumor center either before surgery (n = 78) or immediately after incisional biopsy or marginal excision (n = 41). The tumors were classified according to anatomic location at admittance as subcutaneous (n = 40), intramuscular (n = 30), and extramuscular tumors (n = 49). Open biopsy was omitted in

Adaptable healthcare facilities through modular solutions

The healthcare industry is facing various challenges due to global megatrends, such as increasing average life expectancy, ageing population, technological advancements, urbanization and globalization. Currently, outdated hospital facilities are being thoroughly renovated in large and costly projects to meet contemporary operational requirements. Renovation work in hospital environments is particu

Linking lean to green – energy efficiency as a value stream

Over the past few decades, lean management philosophies have penetrated various sectors of industry. At same time, dynamic environmental, or green, management is needed to succeed in the current green conscious market. Some research has already been conducted on the potential synergy gains of the two management philosophies, since both are known to strive towards efficient use of resources, elimin

Factor VIII : Long-established role in haemophilia A and emerging evidence beyond haemostasis

Factor VIII protein (FVIII) as a coagulation replacement factor has for decades been used as the standard of care for management of people with haemophilia A. It is effective for treatment of bleeding events, as prophylaxis to prevent bleeding events and preserve joint function, and to support surgery in people with haemophilia A. Despite long experience in treating haemophilia A, we are only begi

Elements of Peircean phenomenology : From categories to signs by way of grounds

It is curious facts that Peirce scholars tends to take the three Peircean categories for granted, whereas Peirce himself claimed they must be derived by means of phenomenology, later rebaptized phaneroscopy. As I have suggested elsewhere, this is the essential difference between Peircean and Husserlean phenomenology, which are in other respects identical, whether or not there is a historical conne

Trapping of Gas Bubbles in Water at a Finite Distance below a Water-Solid Interface

Gas bubbles in a water-filled cavity move upward because of buoyancy. Near the roof, additional forces come into play, such as Lifshitz, double layer, and hydrodynamic forces. Below uncharged metallic surfaces, repulsive Lifshitz forces combined with buoyancy forces provide a way to trap micrometer-sized bubbles. We demonstrate how bubbles of this size can be stably trapped at experimentally acces

The effect of Zr loading in Zr/TiO 2 prepared by pressurized hot water on its surface, morphological and photocatalytic properties

Zr/TiO 2 anatase photocatalysts with 0.5, 1, 2, 5 and 7.5 mol.% Zr were prepared using pressurized hot water crystallization and their photocatalytic activity was explored in acid orange 7 photodegradation. Parent TiO 2 was also prepared and tested. From all tested photocatalysts, 2 mol.% Zr/TiO 2 showed the highest photoactivity, and 7.5 mol.% Zr/TiO 2 showed the lowest photoactivity. The po

Data set on sedimentology, palaeoecology and chronology of Middle to Late Pleistocene deposits on the Taimyr Peninsula, Arctic Russia

This Data in Brief paper contains data (including images) from Quaternary sedimentary successions investigated along the Bol’shaya Balakhnya River and the Luktakh–Upper Taimyra–Logata river system on southern Taimyr Peninsula, NW Siberia (Russia). Marine foraminifera and mollusc fauna composition, extracted from sediment samples, is presented. The chronology (time of deposition) of the sediment suThis Data in Brief paper contains data (including images) from Quaternary sedimentary successions investigated along the Bol’shaya Balakhnya River and the Luktakh–Upper Taimyra–Logata river system on southern Taimyr Peninsula, NW Siberia (Russia). Marine foraminifera and mollusc fauna composition, extracted from sediment samples, is presented. The chronology (time of deposition) of the sediment su

Nonrenewable Resources, Strategic Behavior and the Hotelling Rule : An Experiment

We use a laboratory experiment to investigate a novel reason for the lack of empirical support for the Hotelling rule for nonrenewable resources. Specifically, we test whether producers with large resource stocks focus less on the dynamic component of their extraction decision, making them shift extraction to the present and focus more on strategic behavior. Exploiting exogenous variation in stock

The influence of wages on public officials' corruptibility : A laboratory investigation

Previous studies have proposed a link between corruption and wages in the public sector. The present paper investigates this link using a laboratory experiment. In the experiment, public officials have the opportunity to accept a bribe and can then decide between a neutral and a corrupt action. The corrupt action benefits the briber but poses a large negative externality on a charity. The results

Corporate brand positioning in complex industrial firms : Introducing a dynamic, process approach to positioning

Approaches to positioning predominantly examine the input and outcome effectiveness of certain positioning strategies. However, less is known about the positioning management process and internal dynamics. This study remedies this limitation by identifying corporate brand positioning (CBP) in industrial firms as a strategic development process. Based on comparative case studies within two globally