Pparg-Cre.Csf1r-LSL-DTR-mCherry - A new model to study macrophages and monocytes
Macrophages are innate immune cells involved in tissue homeostasis and immunity. They are phagocytes and provide the first line of defense to invading pathogens. Tumors are abundantly populated with macrophages and they are also involved in many autoimmune diseases. Since macrophages play a crucial role in homoeostasis and disease they have emerged as key therapeutic target. However, to manipulate
