AIMS: To evaluate the usefulness of the signed value of monophasic action potential duration difference in analysing the cause of dispersion of ventricular repolarization.METHODS AND RESULTS: Monophasic action potentials were simultaneously recorded from the right ventricular apex and outflow tract during programmed stimulation in 36 patients with ventricular arrhythmias. The time difference betwe

Background: Patients treated for Pediatric Brain Tumors (PBTs) often experience a decline/stagnation in their cognitive functioning.Anumber of potential risk factors for cognitive decline have been identified including gender (female), young age-at-diagnosis, higher baseline IQ, hydrocephalus at diagnosis, treatment with Whole Brain Radiation Therapy (WBRT), and larger radiation field and/or dose.

We show in this Letter a novel approach for high-contrast imaging through scattering media by combining structured illumination and Fourier filtering (SIF). To assess the image contrast enhancement at different image spatial frequencies, the modulation transfer function is calculated for four detection schemes: (1) no filtering, (2) Fourier filtering, (3) structured illumination, and (4) SIF filte

Collaborative filtering for recommender systems seeks to learn and predict user preferences for a collection of items by identifying similarities between users on the basis of their past interest or interaction with the items in question. In this work, we present a conjugate prior regularized extension of Hofmann's Gaussian emission probabilistic latent semantic analysis model, able to overcome th

Solar energy is the most abundant renewable energy source available. Conversion of light into electricity and chemical energy are the two major paths for solar energy conversion. Nanostructured organic and hybrid materials are being explored for applications in photovoltaic solar energy conversion, as well as photocatalysis for solar fuel generation. Light harvesting, energy transport, charge phot

In this work terahertz (THz) pulse emission of the non-vertically aligned GaAs core-shell nanowires (NWs) is investigated. THz emission azimuthal dependencies of different NW samples have been measured. It is shown that these measurements together with theoretical calculations could be a very promising method to determine the effective index of refraction (n0) of the NW ensemble. The measurement o

Next generation sequencing (NGS) methods have been widely used for diagnosis. As time and cost of sequencing has reduced sharply during the last decade, genome and exome-wide sequencing have increasingly been used. The genome and exome projects produce large amounts of variation data and the clinical relevance of large proportions of them are not known. Among various types of genetic variations, t

We present an intensive monitoring of high-resolution spectra of the Ca ii K line in the A7IV shell star φ Leo at very short (minutes, hours), short (night to night), and medium (weeks, months) timescales. The spectra show remarkable variable absorptions on timescales of hours, days, and months. The characteristics of these sporadic events are very similar to most that are observed toward the debr

Introduction Inhibitor development in people with haemophilia is a serious complication that may require intensive and costly interventions. The goal of inhibitor management should be permanent inhibitor eradication through immune tolerance induction (ITI), but well-designed studies are lacking and the management of patients is therefore defined by the experience and views of the clinician. Object

Cognitively-normal people with evidence of β-amyloid (Aβ) pathology and subtle cognitive dysfunction are believed to be at high risk for progression to mild cognitive impairment due to Alzheimer's disease (AD). Clinical trials in later stages of AD typically include a coprimary endpoint to demonstrate efficacy on both cognitive and functional assessments. Recent trials focus on cognitively-normal

Purpose: Individuals with tetraplegia depend on alternative interfaces in order to control computers and other electronic equipment. Current interfaces are often limited in the number of available control commands, and may compromise the social identity of an individual due to their undesirable appearance. The purpose of this study was to implement an alternative computer interface, which was full

The osphradium of molluscs is assumed to be a sensory organ. The present investigation in Lymnaea stagnalis has established two ultrastructurally different types of dendrites in the sensory epithelium. Cells immunoreactive to leucine-enkephalin and FMRFamide send processes to the sensory epithelium. These neurons of the osphradial ganglion are thus considered to be part of the sensory system, as a

The environmental sustainability of cellulosic ethanol production from rice straw in India is conducted using life cycle assessment (LCA). Greenhouse gas (GHG) emissions, net energy ratio (NER) and net energy balance (NEB) are studied for ethanol production system using two diverse pretreatment technologies, i.e. dilute acid (DA) and steam explosion (SE) followed by separate hydrolysis and ferment

Background: Housing environments that hinder performance of daily activities and impede participation in social life have negative health consequences particularly for the older segment of the population. From a public health perspective accessible housing that supports active and healthy ageing is therefore crucial. The objective of the present study was to make an inventory of environmental barr

The mutations of 76 haemophilia B patients representing the whole population registered with the Malmö haemophilia centre (42) and referrals from the UK, were characterised. RFLP haplotype analysis of the defective genes indicated that 51 single base pair substitutions were definitely of independent origin and 27 of these were CpG----TpG or CpA transitions. This represents a 38-fold excess over ot

Cartier identification and antenatal diagnosis were performed in 2 sisters by electrophoretic separation of the normal and abnormal bands obtained after amplification of a fragment of exon h in the factor IX gene. The mutation in the family had been characterised as an 8-base pair (bp) deletion in exon h. By amplification of a 326 bp fragment containing the site of deletion, the shorter 318 bp ban

At Helmholtz-Zentrum Berlin (HZB) the end-station PEAXIS (Photo Electron Analysis and X-ray resonant Inelastic Spectroscopy) combining Angle-dependent X-ray Photoelectron Spectroscopy (AdXPS) and Resonant Inelastic X-ray Scattering (RIXS) is currently built. The latter method uses a spherical variable line space (VLS) grating to focus the beam onto the detector. Working in first-order diffraction