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Improved Estimation of Key Enumeration with Applications to Solving LWE
In post-quantum cryptography (PQC), Learning With Errors (LWE) is one of the dominant underlying mathematical problems. For example, in NIST’s PQC standardization process, the Key Encapsulation Mechanism (KEM) protocol chosen for standardization was Kyber, an LWE-based scheme. Recently the dual attack surpassed the primal attack in terms of concrete complexity for solving the underlying LWE proble
Rational points close to non-singular algebraic curves
We study the density of solutions to Diophantine inequalities involving non-singular ternary forms, or equivalently, the density of rational points close to non-singular plane algebraic curves.
Interface engineering of cellobiose dehydrogenase improves interdomain electron transfer
Cellobiose dehydrogenase (CDH) is a bioelectrocatalyst that enables direct electron transfer (DET) in biosensors and biofuel cells. The application of this bidomain hemoflavoenzyme for physiological glucose measurements is limited by its acidic pH optimum and slow interdomain electron transfer (IET) at pH 7.5. The reason for this rate-limiting electron transfer step is electrostatic repulsion at t
In-situ electrochemical synthesis of heteroatoms-doped reduced graphene oxide toward nonradical degradation of tetracycline
Nonradical-based advanced oxidation processes (AOPs) catalyzed by defective carbonaceous materials have exhibited great superiorities in trace antibiotics removal from natural water matrices. However, the complicated, extensive and highly-energy consumed synthesis methods are seriously hindering its development and application. Herein an in-situ electrochemical synthesis technology was developed a
Do Not Bound to a Single Position: Near-Optimal Multi-Positional Mismatch Attacks Against Kyber and Saber
Misuse resilience is an important security criterion in the evaluation of the NIST Post-quantum cryptography standardization process. In this paper, we propose new key mismatch attacks against Kyber and Saber, NIST's selected scheme for encryption and one of the finalists in the third round of the NIST competition, respectively. Our novel idea is to recover partial information of multiple secret e
Seasonal variations in acidogenic fermentation of filter primary sludge
Primary treatment of municipal wastewater by rotating belt filtration followed by hydrolysis and acidogenic fermentation of the filter primary sludge (FPS) at ambient temperature was studied at pilot-scale during one year. The seasonal variations of volatile fatty acids (VFAs), nutrient release and soluble COD production as well as microbial community assembly were assessed, leading to novel findi
Belief Propagation Meets Lattice Reduction: Security Estimates for Error-Tolerant Key Recovery from Decryption Errors
In LWE-based KEMs, observed decryption errors leak information about the secret key in the form of equations or inequalities. Several practical fault attacks have already exploited such leakage by either directly applying a fault or enabling a chosen-ciphertext attack using a fault. When the leaked information is in the form of inequalities, the recovery of the secret key is not trivial. Recent me
Dual-amplification system based on CRISPR-Cas12a and horseradish peroxidase-tethered magnetic microspheres for colorimetric detection of microcystin-LR
A novel dual-amplification system based on CRISPR-Cas12a and horseradish peroxidase (HRP) was developed for colorimetric determination of MC-LR. This dual-amplification was accomplished by combining the nuclease activity of CRISPR-Cas12a with the redox activity of HRP. HRP linked to magnetic beads through an ssDNA (MB-ssDNA-HRP) was used to induce a color change of the 3,3′,5,5′-tetramethylbenzidi
Genetic studies of paired metabolomes reveal enzymatic and transport processes at the interface of plasma and urine
The kidneys operate at the interface of plasma and urine by clearing molecular waste products while retaining valuable solutes. Genetic studies of paired plasma and urine metabolomes may identify underlying processes. We conducted genome-wide studies of 1,916 plasma and urine metabolites and detected 1,299 significant associations. Associations with 40% of implicated metabolites would have been mi
Challenging the definition of a blood group: Proposal to make CD36 a novel blood group system based on a case report and pre-existing genetic, proteomic and clinical data
Expansion and Biased Commitment of Hematopoietic Stem Cells Towards Erythroid Cells upon Acute Anemia Induction
A Robust Screening Assay For Diamond Blackfan Anemia Candidate Drugs
Impact of metabolic substrate modification on myocardial efficiency in a rat model of obesity and diabetes
BackgroundCongenic leptin receptor deficient rat generated by introgression of the Koletsky leptin receptor mutation into BioBreeding Diabetes Resistant rat (BBDR.lepr−/−) is a novel animal model combining obesity, systemic insulin resistance and diabetes. Systemic insulin resistance is associated with reduced myocardial glucose utilization, but its effect on myocardial external efficiency, i.e. t
Effect of a 3-year lifestyle intervention on telomere length in participants from PREDIMED-Plus : A randomized trial
Background & aims: Short telomeres have been observed in chronic disease patients. Identifying environmental and lifestyle factors that could reduce telomere attrition is crucial for disease prevention. The aim of this work was to determine whether weight-loss induced by an energy-reduced Mediterranean diet (erMedDiet) and physical activity (PA) could modify telomere length (TL). Methods: In 3
Synthesis of phosphine derivatives of [Fe2(CO)6(μ-sdt)] (sdt = SCH2SCH2S) and investigation of their proton reduction capabilities
The reactions of [Fe2(CO)6(μ-sdt)] (1) (sdt = SCH2SCH2S) with phosphine ligands have been investigated. Treatment of 1 with dppm (bis(diphenylphosphino)methane) or dcpm (bis(dicyclohexylphosphino)methane) affords the diphosphine-bridged products [Fe2(CO)4(μ-sdt)(μ-dppm)] (2) and [Fe2(CO)4(μ-sdt)(μ-dcpm)] (3), respectively. The complex [Fe2(CO)4(μ-sdt)(κ2-dppv)] (4) with a chelating diphosphine was
Introduction : Digital Methods and Experiential Approaches to the Past
In this chapter, the authors introduce the theme of computational/digital methods in the realm of sensory archaeologies. To this purpose, the concept of sensoriality and its relevance for the archaeological discourse is rediscussed. Key concepts such as perception of material culture help us in better defining possible modalities through which archaeologists can benefit from the use of formal meth
Rapid and biased evolution of canalization during adaptive divergence revealed by dominance in gene expression variability during Arctic charr early development
Serious Conflicts with Benign Outcomes? The Electoral Consequences of Conflictual Cabinet Terminations
Conflictual cabinet terminations are seismic events in democracies, but their consequences are understudied. I argue that the electoral impacts of conflictual cabinet terminations depend on voters’ perceptions of them. Terminations following non-policy conflicts are electorally costly. They signal parties’ deteriorating governing competence, which reduces parties’ vote shares. In contrast, termina
Don't air your dirty laundry: Party leadership contests and parliamentary election outcomes
Staging an open contest is a democratic method to choose a party leader, though its electoral consequences remain unclear. I argue that leadership contests are electorally detrimental to governing parties. Competitive contests signal intraparty policy and/or personality conflict to voters, which damages governing parties’ perceived unity as well as competence in the policy-making process. Thus, le
