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Low-dose metoprolol CR/XL and fluvastatin slow progression of carotid intima-media thickness: Main results from the Beta-Blocker Cholesterol-Lowering Asymptomatic Plaque Study (BCAPS)

BACKGROUND: Statins reduce cardiovascular events and progression of carotid intima-media thickness (IMT). beta-Blockers are also known to reduce cardiovascular events, but less is known about their effects on carotid IMT. METHODS AND RESULTS: We conducted a randomized, double-blind, placebo-controlled, single-center trial to compare the effects of low-dose metoprolol CR/XL (25 mg once daily) and f

The incidence of retinopathy 10 years after diagnosis in young adult people with diabetes: results from the nationwide population-based Diabetes Incidence Study in Sweden (DISS).

OBJECTIVE—To estimate the prevalence and severity of diabetic retinopathy (DR) 10 years after diagnosis in a nationwide population-based cohort study of young adult diabetic patients in Sweden. RESEARCH DESIGN AND METHODS—The Diabetes Incidence Study in Sweden (DISS) aims to register all incident cases of diabetes aged 15–34 years in Sweden. In 1987–1988, 806 cases were reported, and 627 (78%) of

Svensk talspråkshistoria: tempo och riktning

The article discusses the process of the divergence of Swedish dialects in the Middle Ages and early modern time. Contrary to what is generally believed it is argued that the development is rather slow in the Middle Ages and more rapid afterwards until approximately 1800. Various demographic and other socio-historical factors are proposed as explanations.

Grasping the Peripheral State : A Historical Sociology of Nicaraguan State Formation

The thesis has two aims. The first one is to contribute to the field of political and historical sociology through an understanding of the processes of state formation in a Third World country. The second aim is to describe and analyze the development of the Nicaraguan state from independence to 1990. In the first part of the dissertation theories of the nation-state and state formation are discus

Tyrosyl radicals in enzyme catalysis: Some properties and a focus on photosynthetic water oxidation

Enzymes that require a redox-active amino acid for catalysis or function have emerged as a distinct class of proteins. For the tyrosine-based radical enzymes, we show that the spin-density distribution in the radical follows an odd alternate pattern that is invariant to within 10% across the class. General properties of the radical enzymes are summarized from which we conclude that their essential

Rapidity-alignment and p(T) compensation of particle pairs in hadronic Z(0) decays

Observation is made of rapidity-alignment of K+K- and (p) over barp pairs which results from their asymmetric orientation in rapidity, with respect to the direction from primary quark to antiquark. The K+K- and (p) over barp data are consistent with predictions from the fragmentation string model. However, the (p) over barp data strongly disagree with the conventional implementation of the cluster

Energy-based interference analysis of heterogeneous packet radio networks

While the use of radio technology for wireless data communications has increased rapidly, the wide variety of radio interfaces being used has made interference investigations hard to perform. With that in mind, we present a novel approach for analyzing packet radio communications, applicable to interfering heterogeneous networks, which leads to tractable analytical expressions. The core of the app

Autochthonous versus allochthonous carbon sources of bacteria: Results from whole-lake C-13 addition experiments

Organic substrates for pelagic bacteria are derived from dissolved organic carbon (DOC) in the water column. DOC is a heterogeneous mixture of molecules, some of which are imported from the watershed (allochthonous DOC) and others that are produced by autotrophs within the system (autochthonous DOC). We examined the importance of autochthonous versus allochthonous DOC in supporting the growth of p

Techniques for implementing embedded domain specific languages in dynamic languages

Computer programming should be expressing the complicated in easily understandable parts. General languages provide tools and abstractions that allow many different problems to be formulated and solved. Unfortunately, these abstraction only rarely match the problem area precisely, resulting in solutions that are obscured by the need for support code unrelated to the problem. This can be avoided, b

Tuning energy transfer in the peridinin-chlorophyll complex by reconstitution with different chlorophylls

In vitro studies of the carotenoid peridinin, which is the primary pigment from the peridinin chlorophyll-a protein (PCP) light harvesting complex, showed a strong dependence on the lifetime of the peridinin lowest singlet excited state on solvent polarity. This dependence was attributed to the presence of an intramolecular charge transfer (ICT) state in the peridinin excited state manifold. The I

Entrepreneurship: A Contextual Perspective. Discourses and Praxis of Entrepreneurial Activities within the Institutional Context of Ghana

This study is motivated by the understanding that entrepreneurship varies from one context to another as there are distinctive factors that influence the development and organization of entrepreneurial activities in any particular national context. Using qualitative methodology the study aims at developing a conceptual and empirical framework for the study and understanding of the phenomenon of en

Captures of male European pine sawflies (Hymenoptera : Diprionidae) in pheromone-baited traps in Kentucky

Using sticky traps baited with (2S, 3S, 7S)-3,7-dimethyl-2-pentadecyl acetate, we assessed the seasonal and diurnal flight activity of the European pine sawfly, Neodiprion sertifer (Geoffrey), in Fayette, Madison, and Livingston counties in Kentucky. At each site, two replicates of individual sticky traps were baited and suspended about 1 m high and spaced at least 20 m apart. Trap catch was affec

Radio Wave Propagation in Confined Environments - Measurements and Models

Popular Abstract in Swedish Avhandlingen handlar om hur radiovågor tar sig fram i miljöer där saker som hus, väggar och fönster är i vägen. Framför allt ligger fokus på hur signalen från en sändare placerad utomhus kan nå fram till en mobil terminal (t. ex. en mobiltelefon) som befinner sig inomhus. Hur mycket signalen dämpas när den passerar väggen är av stor betydelse när man ska avgöra hur långThis thesis deals with radio wave propagation in environments where the propagation is severely influenced by surrounding objects, mainly walls and other building structures. As an introduction, a brief description is given on propagation terms like loss, delay and dispersion along with system functions relevant for the topic. The focus is then placed on propagation from an outdoor transmitter to

Analysis of promoter regions of co-expressed genes identified by microarray analysis

Background: The use of global gene expression profiling to identify sets of genes with similar expression patterns is rapidly becoming a widespread approach for understanding biological processes. A logical and systematic approach to study co-expressed genes is to analyze their promoter sequences to identify transcription factors that may be involved in establishing specific profiles and that may