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UV-B-induced DNA damage mediates expression changes of cell cycle regulatory genes in Arabidopsis root tips

Even though a number of studies have shown that UV-B radiation inhibits plant growth and regulates the cell cycle progress, little is known about the molecular and cellular mechanisms. Here, we developed a synchronous root-tip cell system to investigate expression changes of cell cycle marker genes and DNA damage under UV-B radiation. Expression analysis of cell cycle marker genes revealed that G1

Determination of pH or lactate in fetal scalp blood in management of intrapartum fetal distress: randomised controlled multicentre trial

Objective To examine the effectiveness of pH analysis of fetal scalp blood compared with lactate analysis in identifying hypoxia in labour to prevent acidaemia at birth. Design Randomised controlled multicentre trial. Setting Labour wards. Participants Women with a singleton pregnancy, cephalic presentation, gestational age >= 34 weeks, and clinical indication for fetal scalp blood sampling. Inter

Experimental and numerical studies of creasing of paperboard

A laboratory creasing device to capture the most important properties of a commercial rotary creasing tool was designed. Finite element analysis of the creasing of a multiply paperboard in the laboratory crease device was presented. The multiply paperboard was modeled as a multilayered structure with cohesive softening interface model connecting the paperboard plies. The paperboard plies were mode

Bjurkärr – en småländsk bokskog med unika lavar och svampar.

The old beech forest (250–300 yr) at Bjurkärr (core area 30 ha) in the province of Småland, S Sweden, was surveyed for epiphytic lichens of conservation concern in 1993–94. Several rare red-listed lichens were recorded, many with large populations. In 2011 the most endangered lichens were resurveyed due to the incorporation of Bjurkärr in the forthcoming national park of Lake Åsnen. Most species o

Interspecific competition and predation: relative effects on foragers and their densities

Predation and competition are both strong structuring forces in community dynamics, but their relative importance is disputed. In a laboratory experiment, we evaluated the relative importance of competition and predation from juvenile and adult brown trout, respectively, on foraging performance of groups of three stone loaches. We observed loach consumption rate, time spent inactive, and aggressiv

Metric selection in fast dual forward-backward splitting

The performance of fast forward-backward splitting, or equivalently fast proximal gradient methods, depends on the conditioning of the optimization problem data. This conditioning is related to a metric that is defined by the space on which the optimization problem is stated; selecting a space on which the optimization data is better conditioned improves the performance of the algorithm. In this p

Molecular Classification of Bladder Cancer

Popular Abstract in Swedish Cancer i urinblåsan är ett stort hälsoproblem i Sverige och världen. Det är den femte vanligaste cancerformen i Sverige och är den som belastar sjukvården med högst kostnader per patient. Ungefär tre fjärdedelar av de drabbade är män och patienterna är oftast kring 60-80 år gamla. Den behandling vi idag kan erbjuda en person som drabbas av blåscancer har inte förändratsDecisions in the treatment of bladder cancer today are based on clinical and pathological risk variables such as tumor stage and tumor grade. The importance of these conventional risk variables is well documented since more than 10 years, and they are used routinely in the clinics. Over the last ten years, cancer research has seen a gradual transition towards personalized medicine, i.e. the exploi

Designing Public Organizations and Institutions: Essays on Coordination and Incentives

This thesis consists of an introduction and four self-contained chapters that address issues of how organizations and institutions should be designed in order to provide adequate incentives and enable coordination. The first essay uses a multi-task principal-agent model to examine two reasons why coordination problems are common when public sector organizations share responsibilities: the incenti

Ultrafast Dynamics of Hole Injection and Recombination in Organometal Halide Perovskite Using Nickel Oxide as p-Type Contact Electrode.

There is a mounting effort to use nickel oxide (NiO) as p-type selective electrode for organometal halide perovskite-based solar cells. Recently, an overall power conversion efficiency using this hole acceptor has reached 18%. However, ultrafast spectroscopic investigations on the mechanism of charge injection as well as recombination dynamics have yet to be studied and understood. Using time-reso

Satisfactory outcome after intensive chemotherapy with pragmatic use of minimal residual disease (MRD) monitoring in older patients with Philadelphia-negative B cell precursor acute lymphoblastic leukaemia: a Swedish registry-based study

The introduction of minimal residual disease (MRD) monitoring, in the Swedish national guidelines for acute lymphoblastic leukaemia, was evaluated in 35 patients aged 46-79 years (median 61), who were diagnosed from 2007 to 2011 and treated with high-intensity, block-based chemotherapy (ABCDV/VABA induction). Both a high complete remission rate (91 %) and acceptable overall survival (OS) rate (47

Different fractions of human serum glycoproteins bind galectin-1 or galectin-8, and their ratio may provide a refined biomarker for pathophysiological conditions in cancer and inflammatory disease.

BACKGROUND: Changes in glycosylation of serum proteins are common, and various glycoforms are being explored as biomarkers in cancer and inflammation. We recently showed that glycoforms detected by endogenous galectins not only provide potential biomarkers, but also have different functions when they encounter galectins in tissue cells. Now we have explored the use of a combination of two galectin

Social-Psychological Factors in Public Support for Local Biodiversity Conservation

This case study investigates the role of social-psychological variables in the general public's intention to support conservation of five local biotopes. A questionnaire survey of 245 people was carried out in Kristianstad Municipality, Sweden. In hierarchical regression analyses, public intention to support conservation was partly predicted by attitude toward biodiversity conservation and by pers

Modeling Shoreline Evolution at Hai Hau Beach, Vietnam

The coastline of Hai Hau District, located on the northeast coast of Vietnam with about 30 km of shoreline, is chronically eroding. Previous studies have tried to highlight the main causes of the erosion along this coastline, and several hypotheses exist. To examine the hypothesis that gradients in the longshore sediment transport rate and cross-shore fine sediment lost offshore are the main cause

Measurements of the [Formula: see text] production cross sections in association with jets with the ATLAS detector.

This paper presents cross sections for the production of a [Formula: see text] boson in association with jets, measured in proton-proton collisions at [Formula: see text] with the ATLAS experiment at the large hadron collider. With an integrated luminosity of [Formula: see text], this data set allows for an exploration of a large kinematic range, including jet production up to a transverse momentu

Källsortering i historisk miljö

Emelie Fridell Källsortering i historisk miljö För företag och organisationer kan lokalers utformning och platsbrist gör dem mindre lämpade att ställa källsorteringsmöbler i. Detta kan innebära att en del historiska byggnader på grund av sin utformning har svårare att installera källsorteringsmöbler. Vid undersökning av AF-borgen i Lund gjordes en volymbestämning av avfallsmängderna i två lokaThe resources of our earth are limited and need to be managed sustainably. Managing waste is thus a global issue which makes recycling of waste an important part of sustainable resource management. Sweden has come a long way in source separation of waste compared to many other European countries, with recycling techniques and equipment for source separation, in use. However, most studies look at h

Varför ökar självmorden bland barn och unga vuxna? Professioner med inriktning på suicidproblematik och deras tankar om riskfaktorer, samhällsförändring och prevention

The purpose of the following study was to examine professionals’ thoughts of the possible causes regarding suicide among children and young adults in Sweden. The study also includes prevention. Additionally, the study also focuses on the possible causes of suicides among the more overrepresented group boys and young men. The data was collected through six semi-structured interviews with profession

Word-of-Mouth Marketing for Nonprofit Organizations

Word of mouth can be a key growth driver and there is a need for more research on what marketers can do to generate more word of mouth. In particular, nonprofit organizations, that do not have the funds to advertise and rely on traditional media to get attention, could benefit from a better understanding of word-of-mouth marketing. The purpose of this thesis is to identify which factors non

Life Cycle Assessment Framework: Incorporating an extended environmental perspective in the Haldex Project Management Model

Background: An increased concern of environmental issues have made companies, including Haldex, look for new engineering and design practices to keep up with legislations and stakeholder pressure, often by analyzing products’ total environmental impact over their life cycles, in so called life cycle assessment studies. The Haldex Project Management Model is a company specific project model where H