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Desloratadine and loratadine stand out among common H1-antihistamines for association with improved breast cancer survival

Background: As tumors maintain an inflammatory microenvironment, anti-inflammatory medication can be useful in cancer therapy. We have previously shown an association with improved survival in melanoma for use of the H1-antihistamines desloratadine and loratadine, and here we examine use of H1-antihistamines and breast cancer mortality.Material and methods: We investigated use of the six major H1-

Oat Bran Increased Fecal Butyrate and Prevented Gastrointestinal Symptoms in Patients With Quiescent Ulcerative Colitis—Randomized Controlled Trial

Background Oat bran specifically increases colon butyrate concentrations and could therefore affect the progress of the disease in patients with ulcerative colitis (UC). Methods Patients with UC in remission were enrolled in a controlled multicenter study and randomized to eat oat bran or low-fiber wheat products. Results Ninety-four of the enrolled patients (n = 47 for both groups) completed the

Effectiveness of a self-managed digital exercise programme to prevent falls in older community-dwelling adults : study protocol for the Safe Step randomised controlled trial

INTRODUCTION: Exercise interventions have a strong evidence base for falls prevention. However, exercise can be challenging to implement and often has limited reach and poor adherence. Digital technology provides opportunities for both increased access to the intervention and support over time. Further knowledge needs to be gained regarding the effectiveness of completely self-managed digital exer

Cost effectiveness of an intervention focused on reducing bathing disability

The onset of bathing disability among older people is critical for a decline in functioning and has implications for both the individuals' quality of life and societal costs. The aim of this study was to evaluate long-term cost effectiveness of an intervention targeting bathing disability among older people. For hypothetical cohorts of community-dwelling older people with bathing disability, trans

Meeting the needs of elderly with bathing disability

BACKGROUND/AIMS: Difficulties with bathing are frequent among older people and are associated with an increasing need for societal support. As loss of independence has a negative impact on health and wellbeing, it is important to study interventions that can provide the required support for people to be able to remain independent. Occupational therapy interventions can improve clients' abilities e

Monitoring of cerebral oximetry in patients with postural orthostatic tachycardia syndrome

AIMS : Postural orthostatic tachycardia syndrome (POTS) is a disorder of unknown aetiology characterized by orthostatic intolerance and tachycardia with diverse other symptoms, including neurocognitive deficits. Cerebral oximetry non-invasively measures cerebral tissue saturation (SctO2) and has been shown to be informative in syncope evaluation. We aimed to assess SctO2 in POTS patients and those

Overview of some feedback-&control systems at synchrotron SolEIL

This paper gives an overview of some feedback & control systems at Synchrotron SOLEIL that are in use or in development today. Beam stability is crucial and adressed in all SOLEIL aspects; Fast Orbit Feedback is a multi-input multi-output control system made to stabilize beam position perturbations in the low- & high frequency band. In addition, active RF cavities are used to maintain stab

Thermal assessment for prostheses : State-of-the-art review

Hundreds of young people have had limbs amputated after being wounded by civil wars, explosions or gunshots. Heat and perspiration within a prosthetic socket are the most common side effects of reduced quality life for prosthesis. Besides, the environment between liner and skin is an ideal host of residual limb skin problems such as contact dermatitis and bacterial infections. It is important to m

From Exclusion to Inclusion—a Stepwise Process : a Qualitative Study of How the Reintegration Process Is Experienced by Young People Previously Living on Streets in the Kagera Region, Tanzania

The aim is to explore how young people, after having lived on the streets, experience the reintegration process of returning to their local community. Individual interviews were conducted with young males having experience of reintegration after having lived on the streets. The results show a step-wise process initially signified by ambivalence, moving back and forth and encountering setbacks. The