A peptidomimetic called A20 (Cystapep 1) structurally based upon the N-terminal fragment of human cystatin C is known to have strong antibacterial properties. A20 is characterized by high activity against several bacterial strains often isolated from infected wounds, including methicillin-resistant S. aureus (MRSA). In this work we wanted to explore the therapeutic potential of A20 in the treatmen

Idag tillhör persondatorerna våra käraste prylar, men så har det inte alltid varit. Kring 1980, då persondatorerna slog igenom i Sverige, sågs "datafrågorna" istället tillhöra samhällets stora utmaningar, tillsammans med bland annat energiförsörjningen och miljöfrågorna. Dessa datafrågor debatterades häftigt, och i fackpressen kritiserades särskilt Sveriges Television för att ge en alldeles för dy

Universal Serial Bus (USB) is a new interface standard for connecting peripheral devices to personal computers. A USB system consists of a host (typically a PC) and a number of peripherals with USB interfaces.In this thesis, we have investigated an alternative approach to the PC based system. We have developed a camera server which connects a USB camera directly to Ethernet. The server is an indep

Prostate cancer (PCa) has a large familial component, but understanding of its genetic basis is fragmentary. Breast cancers may be associated with PCa, but whether this is true for other tumor types is poorly established. We used a novel approach to study familial associations of any type of cancer with PCa. We assessed the relative risk (RR) for all types of tumors as a function of the number of

Introduction: The development of neutralizing antibodies (inhibitors) against coagulation factor VIII (FVIII) is currently the most serious complication for patients with haemophilia A undergoing FVIII replacement therapy. Several genetic factors have been acknowledged as risk factors for inhibitor development. Aim: To analyze the influence of genetic factors on the nature of the humoral immune re

Organisms in hot environments will not be able to passively dissipate metabolically generated heat. Instead, they have to revert to evaporative cooling, a process that is energetically expensive and promotes excessive water loss. To alleviate these costs, birds in captivity let their body temperature increase, thereby entering a state of hyperthermia. Here we explore the use of hyperthermia in wil

To understand how the specialisation patterns of cities differ among scientific fields, we study patterns of knowledge production in Astrophysics, Biotechnology, Nanotechnology and Organic Chemistry in the period 1996-2012. Using keywords from journal publications, we find systematic differences across scientific fields, but remarkable similarities across cities within each field. Biotechnology sh

Heckscher published in 1915 a book on the economics of World War I in Swedish. He analyzed the costs and the finances of war along similar lines as his contemporary Pigou (1916). Heckscher reached farther by making a distinction between the short and the long-run costs of war. He also provided a comprehensive theoretical and empirical analysis of the sources of funds for war finance, including a pHeckscher published in 1915 a book on the economics of World War I in Swedish. He analyzed the costs and the finances of war along similar lines as his contemporary Pigou (1916). Heckscher reached farther by making a distinction between the short and the long-run costs of war. He also provided a comprehensive theoretical and empirical analysis of the sources of funds for war finance, including a p

BACKGROUND: In 2008, the Swedish government introduced a National Rehabilitation Program, in which the government financially reimburses the county councils for evidence-based multimodal rehabilitation (MMR) interventions. The target group is patients of working age with musculoskeletal disorders (MSD), expected to return to work or remain at work after rehabilitation. Much attention in the evalua

The transnational and transmedial dimensions of media and communication throughout history have not always been adequately recognised. In this research report we propose the concept of entanglement as a means of better understanding the dynamic interconnectedness of media across semiotic, technological, institutional and political boundaries in history. Entanglement is a concept that can be employThe transnational and transmedial dimensions of media and communication throughout history have not always been adequately recognised. In this research report we propose the concept of entanglement as a means of better understanding the dynamic interconnectedness of media across semiotic, technological, institutional and political boundaries in history. Entanglement is a concept that can be employ