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Long-term efficacy and safety of α1 proteinase inhibitor treatment for emphysema caused by severe α1 antitrypsin deficiency : an open-label extension trial (RAPID-OLE)

Background Purified α1 proteinase inhibitor (A1PI) slowed emphysema progression in patients with severe α1 antitrypsin deficiency in a randomised controlled trial (RAPID-RCT), which was followed by an open-label extension trial (RAPID-OLE). The aim was to investigate the prolonged treatment effect of A1PI on the progression of emphysema as assessed by the loss of lung density in relation to RAPID-

Sustainable Consumption and Value Propositions: Exploring Product–Service System Practices Among Swedish Fashion Firms

Since sustainable consumption (SC) research focuses primarily on consumer purchasing behaviors, there is a gap regarding how firms attempt to shape sustainable consumption in practice. Utilizing nine case studies, this gap is addressed by exploring the use of value propositions entailing product–service systems among Swedish fashion firms. The value propositions in use by the firms suggest that su

Effects of pitch and corrugation depth on heat transfer characteristics in six-start spirally corrugated tube

Spirally corrugated tube is one of the most important parts of coaxial heat exchangers. It can greatly improve the heat transfer efficiency of heat exchangers. Here, a novel spirally corrugated tube with six-start is proposed. However, up to now, there is little literature about the heat transfer performance and flow field of this novel six-start spirally corrugated tube. In this paper, the effect

Nya Namn i Periodiska Systemet

Artikeln ger en sammanfattning av IUPAC:s rekommendationer år 1994 för namnen på de nya grundämnena 101-109, de s.k. transfermierna. Rekommendationerna publiceras senare under 2014 i Pure and Applied Chemistry, Vol 66 Nr 12. Dessa rekommendationer skall under år 1995 ytterligare granskas/ratificeras av IUPACs Council, vilket slutligen kan resultera i ändringar eller omflyttningar.

Probing Atomic Scale Structure and Catalytic Properties of Cobalt Oxide Model Catalysts

Catalysts are used to produce a large fraction of the materials we use in our modern society. Avery famous example is the highly efficient catalysts that are used to fix nitrogen from the air intoartificial fertilizer salts. Without this catalytic process, it is difficult to imagine that we could feedthe current population of earth. Artificial fertilizers are, however, not the only product that usCobalt oxides are known to be active catalysts for a number of chemical reactions, but very little is known about the atomic scale processesresponsible for the activity. The research presented in this thesis is focused on obtaining an atomic scale understanding of the chemistry of wellcharacterizedcobalt oxide model catalyst surfaces consisting of pristine and defective CoO and Co3O4 thin films wi

Ultrasonic additive manufacturing A hybrid production process for novel functional products

Ultrasonic Additive Manufacturing (UAM), or Ultrasonic Consolidation as it is also referred, is a hybrid form of manufacture, primarily for metal components. The unique nature of the process permits extremely novel functionality to be realised such as multi-material structures with embedded componentry. UAM has been subject to research and investigation at Loughborough University since 2001. This

Ultrasonic additive manufacturing research at loughborough university

Ultrasonic Additive Manufacturing (UAM) has been subject to research and investigation at Loughborough University since 2001. In recent years, three particular areas of significant focus have been: The influence of pre-process material texture on interlaminar bonding. Secure fibre positioning through laser machined channels. Freeform electrical circuitry integration. This paper details the key fin

A combinatory antibody-antigen microarray assay for high-content screening of single-chain fragment variable clones from recombinant libraries

We have developed a combinatory antibody-antigen microarray for direct screening of multiple single-chain fragment variable (scFv) clones with no need for pre-purification or enrichment before screening. The straightforward workflow allows for early selection of binders to predefined peptide and glycopeptide targets. A capture antibody is contact printed on microarray slides, side by side with the

Anticipating future risk in social-ecological systems using fuzzy cognitive mapping : The case of wildfire in the Chiquitania, Bolivia

Understanding complex social-ecological systems, and anticipating how they may respond to rapid change, requires an approach that incorporates environmental, social, economic, and policy factors, usually in a context of fragmented data availability. We employed fuzzy cognitive mapping (FCM) to integrate these factors in the assessment of future wildfire risk in the Chiquitania region, Bolivia. In

Cost and clinical outcome of islet transplantation in Norway 2010-2015

Islet transplantation is a minimally invasive β-cell replacement strategy. Islet transplantation is a reimbursed treatment in Norway. Here, we summarize the cost and clinical outcome of 31 islet transplantations performed at Oslo University Hospital (OUS) from January 2010 to June 2015. Patients were retrospectively divided into three groups. Thirteen patients received either one or two islet tran