Exploring galectin non-carbohydrate inhibitors by computational analysis and synthesis
Galectins are in the centre of an intricate communications system within the cells and designing inhibitory ligands for them has proved useful in discerning the expression and retardation of various diseases. Galectins traditionally bind via carbohydrate recognition domains to carbohydrate ligands. Currently, only limited research has been conducted in regard of finding suitable glycomimetic ligan
