The complement system constitutes a crucial part of the innate immunity, mediating opsonization, lysis, inflammation, and elimination of potential pathogens. In general, there is an increased activity of the complement system during pregnancy, which is essential for maintaining the host’s defense and fetal survival. Unbalanced or excessive activation of the complement system in the placenta is ass

The main characteristic of postural orthostatic tachycardia syndrome (POTS) is tachycardia when standing, without a drop in blood pressure. Patients describe lightheadedness and palpitations when upright, particularly when standing, which sometimes leads to syncope. Patients may experience impaired quality of life and functional disability, which can be economically devastating.1–3 The syndrome is

Economic analysis has produced ample insights on how international trade and climate policy interact. Trade presents both opportunities and obstacles, and invites the question of how domestic climate policies can be effective in a global economy integrated through international trade. Particularly problematic is the potential relocation of production to regions with low climate standards. Measures

The present paper reports findings from a controlled large-scale (N = 1018) experimental study investigating how four different gender-fair forms influenced native French speakers’ estimated percentage of women compared to the masculine form (interpretable as generic) in 22 non-stereotyped French role nouns. The findings show that the masculine form generated lower perceived percentages of women c

This city report is the result of a Mobile Research Lab conducted online in Shanghai during spring 2020. The Mobile Research Lab involves a combination of methods, including case studies, interviews, observations, expert panels, and in-situ field work. This report presents insights gained by the Urban Sharing research team Oksana Mont (PI), Andrius Plepys, Yuliya Voytenko Palgan, Matthias Lehner,

Six different films published on https://www.shareable.net/:-The roles of city governments in the sharing economy-Regulating the sharing economy in cities-How municipalities self-govern in the sharing economy-How municipalities provide for the sharing economy-How municipalities enable or disable the sharing economy-How municipalities govern the sharing economy through collaboration

Control of crop pests by shifting host plant availability and natural enemy activity at landscape scales has great potential to enhance the sustainability of agriculture. However, mainstreaming natural pest control requires improved understanding of how its benefits can be realized across a variety of agroecological contexts. Empirical studies suggest significant but highly variable responses of n

The #FridaysForFuture climate protests mobilized more than 1.6 million people around the globe in March 2019. Through a school strike, a new generation has been galvanized, representing a historical turn in climate activism. This wave of climate protest mobilization is unique in its tactics, global scope and appeal to teenage school students. Media coverage of these protests and high-level nationa

Using data from southern Sweden, this work analyses the development of maternal and infant health in five rural parishes and the town of Landskrona in Scania, Sweden, in the last 110 years. First, we address the overall development of maternal, perinatal and infant health using a range of indicators, such as maternal mortality, neonatal mortality, and stillbirth rates. We also describe how institu

A 27-years-old female with multiple autoimmune disorders presented to our cardiology unit for acute chest pain and worsening dyspnoea. Admission blood tests revealed increased serum levels of high-sensitive cardiac troponin, eosinophilic count and C-reactive protein. Laboratory findings, low QRS voltages by ECG, mildly reduced left ventricular systolic function in the context of pseudohypertrophy,

In the philosophy of J. L. Schellenberg, “evolutionary religion” is a religious stance oriented towards the deep future. According to Schellenberg, the best form of evolutionary religion is non-doxastic faith in ultimism. I reject Schellenberg’s arguments for preferring ultimism and suggest that committing non-doxastically to traditional religion makes more sense from an evolutionary perspective.

This article explores how the acceleration of social time shapes the everyday work of museum and library professionals in Estonia and Sweden. Informed by theories on social acceleration and principles of constructivist grounded theory, 34 semi-structured in-depth interviews were carried out. The ‘symptoms’ of the acceleration of social time create several temporal tensions in organizations, theref

The Solar System’s orbital structure is thought to have been sculpted by an episode of dynamical instability among the giant planets1–4. However, the instability trigger and timing have not been clearly established5–9. Hydrodynamical modelling has shown that while the Sun’s gaseous protoplanetary disk was present the giant planets migrated into a compact orbital configuration in a chain of resonan

The throughput of macromolecular X-ray crystallography experiments has surged over the last decade. This remarkable gain in efficiency has been facilitated by increases in the availability of high-intensity X-ray beams, (ultra)fast detectors and high degrees of automation. These developments have in turn spurred the development of several dedicated centers for crystal-based fragment screening whic