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Towards Precise Localisation : Subsample Methods, Efficient Estimation and Merging of Maps

Over the last couple of years audio and radio sensors have become cheaper and more common in our everyday life. Such sensors can be used to form a network, from which one can obtain distance measures by correlating the different received signals. One example of such distance measures is time-difference of arrival measurements (TDoA), which can be used to estimate the positions of the senders and r

Sensations, symptoms, and then what? Early bodily experiences prior to diagnosis of lung cancer

Lung cancer (LC) generally lacks unique core symptoms or signs. However, there are a multitude of bodily sensations that are often non-specific, not easily understood, and many times initially not recognized as indicative of LC by the affected person, which often leads to late diagnosis. In this international qualitative study, we inductively analyzed retrospective accounts of 61 people diagnosed

Measurement of light-by-light scattering and search for axion-like particles with 2.2 nb−1 of Pb+Pb data with the ATLAS detector

This paper describes a measurement of light-by-light scattering based on Pb+Pb collision data recorded by the ATLAS experiment during Run 2 of the LHC. The study uses 2.2 nb−1 of integrated luminosity collected in 2015 and 2018 at sNN = 5.02 TeV. Light-by-light scattering candidates are selected in events with two photons produced exclusively, each with transverse energy ETγ> 2.5 GeV, pseudorapidi

Imaging meets cytometry : Analyzing heterogeneous functional microscopic data from living cell populations

Biological tissue consists of populations of cells exhibiting different responses to pharmacological stimuli. To probe the heterogeneity of cell function, we propose a multiplexed approach based on real-time imaging of the secondary messenger levels within each cell of the tissue, followed by extraction of the changes of single-cell fluorescence over time. By utilizing a piecewise baseline correct

Dislocation of hemiarthroplasty after hip fracture is common and the risk is increased with posterior approach : result from a national cohort of 25,678 individuals in the Swedish Hip Arthroplasty Register

Background and purpose — Reported revision rates due to dislocation after hemiarthroplasty span a wide range. Dislocations treated with closed reduction are rarely reported despite the fact that they can be expected to constitute most of the dislocations that occur. We aimed to describe the total dislocation rate on the national level, and to identify risk factors for dislocation. Patients and met

Association of Preterm Birth with Long-term Risk of Heart Failure into Adulthood

Importance: Preterm birth has been associated with increased risk of heart failure (HF) early in life, but its association with new-onset HF in adulthood appears to be unknown. Objective: To determine whether preterm birth is associated with increased risk of HF from childhood into mid-adulthood in a large population-based cohort. Design, Setting, and Participants: This national cohort study was c

Late-time Observations of Calcium-rich Transient SN 2019ehk Reveal a Pure Radioactive Decay Power Source

We present multiband Hubble Space Telescope imaging of the calcium-rich supernova (SN) SN 2019ehk at 276-389 days after explosion. These observations represent the latest B-band to near-IR photometric measurements of a calcium-rich transient to date and allow for the first opportunity to analyze the late-time bolometric evolution of an object in this observational SN class. We find that the late-t

Endocrine disrupting chemicals and breast cancer : a systematic review of epidemiological studies

Background: Endocrine-disrupting compounds (EDCs) are ubiquitous substances that are found in our everyday lives, including pesticides, plasticizers, pharmaceutical agents, personal care products, and also in food products and food packaging. Increasing epidemiological evidence suggest that EDCs may affect the development or progression of breast cancer and consequently lead to lifelong harmful he

Ghost QTL and hotspots in experimental crosses : novel approach for modeling polygenic effects

Ghost quantitative trait loci (QTL) are the false discoveries in QTL mapping, that arise due to the "accumulation" of the polygenic effects, uniformly distributed over the genome. The locations on the chromosome that are strongly correlated with the total of the polygenic effects depend on a specific sample correlation structure determined by the genotypes at all loci. The problem is particularly

Unmanned Aerial Vehicle Benefit Assessment for the Structural Integrity Management of Wind Turbines

Unmanned Aerial Vehicles (UAVs) equipped with high-resolution image recording devices have found recent application in performing inspection and surveillance of buildings, bridges, wind parks and other civil infrastructure systems. With the concept of equipping a UAV with NDE equipment, possibilities are created for new research areas in the field of structural health monitoring, where a limited n

Genetic Diversity and Population Structure in Bryophyte With Facultative Nannandry

Among plants, gender dimorphism occurs in about 10% of all angiosperms and more than 50% of all moss taxa, with dwarf males (DM) found exclusively in some unisexual mosses. In this study, we explore the role of male dwarfism as a reproductive strategy in the widespread acrocarpous moss Dicranum scoparium, which has facultative male dwarfism, having both dwarf males (DMs) and normal-sized males (NM

Evaluating the Effects of SARS-CoV-2 Spike Mutation D614G on Transmissibility and Pathogenicity

Global dispersal and increasing frequency of the SARS-CoV-2 spike protein variant D614G are suggestive of a selective advantage but may also be due to a random founder effect. We investigate the hypothesis for positive selection of spike D614G in the United Kingdom using more than 25,000 whole genome SARS-CoV-2 sequences. Despite the availability of a large dataset, well represented by both spike

Simulations of light collection in long tapered CsI(Tl) scintillators using real crystal surface data and comparisons to measurement

Simulation results for light transport in long tapered CsI(Tl) crystals using look-up tables (LUTs) are presented. The LUTs were derived from the topography of a polished and a lapped surface of a CsI(Tl) crystal measured with atomic force microscopy. Simulations with different combinations of polished and lapped surfaces were performed, to extract the non-uniformity of light collection depending

Breast cancer in young women. Aspects of heredity and contralateral disease.

Breast cancer is the most commonly diagnosed cancer among women in Sweden, as well as worldwide. In Sweden, 8,288 women were diagnosed with invasive breast cancer in 2019, out of whom approximately 1.5% were younger than 35 years of age. Although breast cancer is relatively uncommon in young women, they tend to be diagnosed with more aggressive tumors at a more advanced stage, and have a poorer pr

Pro-IL-1β Is an Early Prognostic Indicator of Severe Donor Lung Injury During Ex Vivo Lung Perfusion

BACKGROUND: Ex vivo lung perfusion (EVLP) is used to evaluate and recondition extended criteria donor lungs for transplantation. Interleukin-1β (IL-1β) has been identified as a prognostic indicator of nonrecovery during EVLP. This may be an effect of inflammasome activation or cellular necrosis following donation and graft preservation. Delineating the mechanism of IL-1β release is required. METHO

The Vbeta13 T Cell Receptor Monoclonal Antibody Reduces Hyaluronan and CD68+, CD3+, and CD8+ Cell Infiltrations to Delay Diabetes in Congenic BB DRLyp/Lyp Rats

The depleting Vβ13a T cell receptor monoclonal antibody (mAb) 17D5 prevents both induced and spontaneous autoimmune diabetes in BB rats. Here it was tested in congenic DRLyp/Lyp rats, all of which spontaneously developed diabetes. Starting at 40 days of age, rats were injected once weekly with either saline, His42 Vβ16 mAb, or 17D5 mAb and monitored for hyperglycemia. Diabetes occurred in 100% (n