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Perioperative management and anaesthetic considerations in pelvic exenterations using Delphi methodology : results from the PelvEx Collaborative
BACKGROUND: The multidisciplinary perioperative and anaesthetic management of patients undergoing pelvic exenteration is essential for good surgical outcomes. No clear guidelines have been established, and there is wide variation in clinical practice internationally. This consensus statement consolidates clinical experience and best practice collectively, and systematically addresses key domains i
Sex is overrated: : On the right to reproduce
I will show that what is respected the most in human reproduction and parenting is not a right to reproduce in the way in which this right is explicitly proposed. The only way in which people can become, and function as, parents without having to submit themselves to anyone else’s judgments and decisions, is by having reproductive sex. Whatever one’s intentions, social status, standard of living,
On a Romanian attempt to legislate on medically assisted human reproduction
The paper presents and briefly analyses some of the provisions of a Romanian legislative proposal which arrived at the Presidency for ratification twice, in slightly different forms, and which was rejected twice: the first time at the Presidency in October 2004, and the second at the Constitutional Court in July 2005. The proposal was finally dropped in February 2006. My intention here is to point
Reproductive and parental autonomy: : an argument for compulsory parental education
In this paper we argue that comprehensive and systematic parental education has the potential to equip young adults with the necessary information for the responsible exercise of their autonomy in choices about reproduction and parenting. Education can allow young adults to acquire largely accurate beliefs about reproduction and parenting and about the implications of their reproductive and parent
Increased 25-hydroxyvitamin D3 1alpha-hydroxylase and reduced 25-hydroxyvitamin D3 24-hydroxylase expression in parathyroid tumors--new prospects for treatment of hyperparathyroidism with vitamin d
Vitamin D analogues are in clinical use for prevention and treatment of secondary hyperparathyroidism (HPT) in chronic renal failure. Despite recent advances there is a need for vitamin D derivatives with maintained parathyroid hormone suppressive activity and less hypercalcemic and hyperphosphatemic toxicity. Here we show coincident increased expression of the vitamin D activating enzyme 25-hydro
Life extension, overpopulation and the right to life: against lethal ethics
Some of the objections to life-extension stem from a concern with overpopulation. I will show that whether or not the overpopulation threat is realistic, arguments from overpopulation cannot ethically demand halting the quest for, nor access to, life-extension. The reason for this is that we have a right to life, which entitles us not to have meaningful life denied to us against our will and which
Immortal Fetuses
In this article I look at two hypothetical examples with the purpose of challenging some of the underlying intuitions that affect our views on immortality.
The ethics of ageing, immortality and genetics
Looking for a Meaning of Dignity in the Bioethics Convention and the Cloning Protocol
This paper is focused on the analysis of two documents (the Council of Europe's Bioethics Convention and the Additional Cloning Protocol) inasmuch as they refer to the relationship between human dignity and human genetic engineering. After presenting the stipulations of the abovementioned documents, I will review various proposed meanings of human dignity and will try to identify which of these se
Postmenopausal motherhood: immoral, illegal? A case study
The paper explores the ethics of post-menopausal motherhood by looking at the case of Adriana Iliescu, the oldest woman ever to have given birth (so far). To this end, I will approach the three most common objections brought against the mother and/or against the team of healthcare professionals who made it happen: the age of the mother, the fact that she is single, the appropriateness of her motiv
Om musikers lyssnande
Recension av: Stefan Östersjö, 2021. Listening to the Other, 184 s. Leuven: Leuven University Press. ISBN: 978-94-6270-229-5.
National Adoption of International Financial Reporting Standards : The case of China
In the past few decades, there has been a global trend of international harmonization of accounting standards, with many countries having either partially or completely replaced their national accounting standards with the International Financial Reporting Standards (IFRS). The intended goal is to remove the barriers that hinder investors when comparing accounting information of companies from dif
Dexamethasone eye-drops for treatment of retinopathy of prematurity
Both studies on animals and humans have demonstrated the role of inflammatory mediators on the retinopathy process.2,3 Dexamethasone is a glucocorticoid with a known reductive effect on several of these mediators and on the expression of VEGF.4Starting in 2016, infants receiving laser ablation for type 1 ROP at Skåne University Hospital were administered dexamethasone eye-drops postoperatively, us
Deregulation and editing of microRNAs in metastatic prostate cancer
Prostate cancer bone metastasis is still not fully understood, and increased knowledge could aid in the development of better treatment options for patients in the future. This thesis focuses on microRNAs (miRNAs), which modulate gene expression in healthy and tumour cells. Using cell culture, animal and patient studies, we investigated the biological role of microRNA-96 (miR-96) and microRNA-379
Remissyttrande: promemoria Tillfälligt omhändertagande av villkorligt frigivna och skyddstillsynsdömda
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The book comprises three parts: (1) a general presentation and analysis of the main relevant concepts: bioethics, human genetic engineering, eugenics, disability and, particularly, of the relations between these; (2) the analysis of two documents of the Council of Europe (the so called “Bioethics Convention” and its first protocol), and the reconstruction of the debates surrounding their primary c
Oncologic and reproductive outcome and Quality of Life after robot-assisted surgery for early stage cervical cancer. Evaluation of radical hysterectomy and radical trachelectomy.
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Über sociale Differenzierung ist Georg Simmels erstes hauptsächlich der Soziologie gewidmetes Werk. Das Buch stellt Simmels Grundlegung der neuen Wissenschaft dar, ihrer Themen, Möglichkeiten, Grenzen, allgemeinen Begriffe und Annahmen. Soziale Differenzierung, Wechselwirkung, Individualisierung, Gruppe, Vergesellschaftung und Bewegung sind entscheidende, variable Begriffe dieses zwischen Grundleg