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Progenitor cells in the postnatal central nervous system, characterization and genetic manipulation

New neurons are only generated in two places of the postnatal brain; the subventricular zone (SVZ) and hippocampus. The SVZ-derived cells specifically migrate to the olfactory bulb where they give rise to new interneurons. We have genetically manipulated the postnatal SVZ progenitor cells with the aim to direct them to a neuronal fate in the striatum. Our result showed that ectopic expression of t

Pain in older adults living in sheltered accommodation--agreement between assessments by older adults and staff

This study aimed to investigate the presence of pain, pain duration, localization(s), intensity, type and pharmacological treatment among older adults living in sheltered accommodation or receiving rehabilitation, as well as the agreement between pain assessments performed by staff and the older adults. Twenty-nine randomly selected older adults (65+ years) and the staff who looked after them part

Beneficial effects of ACTH on the serum lipoprotein profile and glomerular function in patients with membranous nephropathy

BACKGROUND: Previous studies have shown that short-term treatment with adrenocorticotrophic hormone (ACTH) has a strong and rapid lipid-lowering effect. In this long-term study of nephrotic patients with idiopathic membranous nephropathy, the influence of ACTH on the serum lipoprotein profile and glomerular function as well as the dose-effect relationship was investigated. METHODS: Fourteen patien

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Popular Abstract in Swedish Med föreliggande avhandling vill jag belysa att Chrétien de Troyes Graalsaga, till skilnad från vad de åtskilliga kritiker har påstått, inte bygger på traditionella ridderliga värden, men väl avslöjar en problematisk ideologi. Denna ideologi prövas med hjälp av V. Jouves metod, som beskrivs i hans Poétique des valeurs. Graalsagans värden analyseras ur ett dubbelt perspThis dissertation aims at showing that Chrétien de Troyes' Conte du Graal does not, as often affirmed, uphold traditional chivalrous values, but discloses a problematic ideology, mostly as a result of multiple interactions at the textual level. In order to examine ideology, Le Conte du Graal is analysed in the light of the poetics elaborated by Vincent Jouve in his Poétique des valeurs (2001). Fol

Determination of the pore-size distribution in gels

A method for determination of the accessible volume fraction in gels as function of the molecular weight of the solutes is presented. The pore-size distribution is determined by measuring the rate of diffusion of a mixture of solutes into a gel using gel filtration for separation. The solutes, of various sizes, are detected by refractive index measurements. Two marker molecules (blue dextran and g

Adaptations for vision in dim light: impulse responses and bumps in nocturnal spider photoreceptor cells (Cupiennius salei Keys)

The photoreceptor cells of the nocturnal spider Cupiennius salei were investigated by intracellular electrophysiology. (1) The responses of photoreceptor cells of posterior median (PM) and anterior median (AM) eyes to short (2 ms) light pulses showed long integration times in the dark-adapted and shorter integration times in the light-adapted state. (2) At very low light intensities, the photorece

Att arbeta i dödens närhet : Rutiner och ritualer i äldreomsorg

This study is based mainly on observations and interviews accomplished on two occasions with nursing assistants employed at two group living units for older people suffering from dementia in Sweden. The interviews and observations were carried out one year apart, before and after a project that also included supervision of managers and nursing assistants. I interviewed 12 nursing assistants, 8 of

Patient satisfaction after knee arthroplasty: a report on 27,372 knees operated on between 1981 and 1995 in Sweden

During a validation process of the Swedish Knee Arthroplasty Register (SKAR), living registered patients were sent a questionnaire to ask if they had been reoperated on. This gave an opportunity to pose a simple four-point question with respect to patient satisfaction which 95% of patients answered. We analyzed the answers of patients operated on between 1981 and 1995 and found that only 8% of the

Finite boson and fermion systems under extreme rotation: edge reconstruction and vortex formation

Vortices can form when finite quantal systems are set rotating. In the limit of small particle numbers, the vortex formation in a harmonically trapped fermion system, with repulsively interacting particles, shows similarities to the corresponding boson system, with vortices entering the rotating cloud for increasing rotation. For a larger number of fermions, N greater than or similar to 15, the fe

Review of John Ternstedt, "Några anteckningar om mitt liv". Skara 1999

John Ternstedt (1844-1938) var en av de relativt få svenska präster som påverkades av Tübingerteologen J. T. Beck. Dessa kortfattade anteckningar innehåller inga teologiska analyser, men ger tydliga intryck av spiritualiteten i dessa kretsar med dragning åt mystik och distans till nyevangelismen. Vi får inblickar i såväl skolelevens som lantprästens tillvaro i en tid då präst och församlingsbor va

Regulation of MUC5AC mucin secretion by depletion of AQP5 in SPC-A1 cells

Airway mucus is regulated by many inflammatory mediators such as ILs, TNF-alpha, EGF, PGF2 alpha, LT, and so on. Recently, the relationship between membrane ion channel and Mucus production has been under investigation. The present study aimed to examine whether AQP5 was involved in modulation of mucin expression and secretion in airway submucosal gland cells (SPC-Al). A recombinant plasmid (pShAQ

Growth of inoculated white-rot fungi and their interactions with the bacterial community in soil contaminated with polycyclic aromatic hydrocarbons, as measured by phospholipid fatty acids

The objective of this study was to examine the possibility of measuring the growth of three white-rot fungi in soil contaminated with polycyclic aromatic hydrocarbons (PAHs), by estimating the soil levels of the phospholipid fatty acid (PLFA) 18:2ω6,9. The effect of the fungi on the PAH concentration and on the indigenous bacterial population in the soil was monitored. As shown by visual examinati

MR-undersökning av hjärnan vid 3 tesla. Högre magnetfältsstyrka ger bättre morfologisk och funktionell bild

Magnetresonansundersökning med magnetfältsstyrka 3 tesla (3T-MR) ger förbättrade morfologiska och funktionella undersökningar av hjärnan jämfört med de mer vanligt förekommande MR-utrustningarna med fältstyrkan 1,5T eller lägre. Fördelarna med 3T dominerar enligt vår mening markant över vissa nackdelar som den högre fältstyrkan också medför. Kombination med ett kraftfullt gradientsystem ger optima3T MRI offers improved morphological and functional studies of the brain compared with the more commonly used field strength 1.5T. Clinical 3T MRI of the brain is beneficial for high resolution morphological imaging, MR angiography, diffusion-MRI including diffusion tensor imaging, perfusion-MRI, functional MRI (fMRI), and MR spectroscopy. The performance is enhanced by the combination with powerf

Rotational Bands in 77Rb: Spectroscopy Near the Z=38 Deformed Shell Gap

The gamma decays of high spin states in Rb-77 populated in the reaction Ca-40(Ca-40,3p) Rb-77 were studied with the EUROGAM I gamma-ray spectrometer at Daresburp Laboratory, in conjunction with the recoil mass separator. The data were used to extend or establish three positive parity and five negative parity bands in Rb-77. Levei lifetimes and sidefeeding times were then measured with the NORDBALL