It is commonly assumed that algorithmic curation of search results creates filter bubbles, where users’ beliefs are continually reinforced and opposing views are suppressed. However, empirical evidence has failed to support this hypothesis. Instead, it has been suggested that filter bubbles may result from individuals engaging selectively with information in search engine results pages. However, t

Background: Growth differentiation factor 15 (GDF-15) has been associated with the risk of developing major bleedings, including but not restricted to intracranial hemorrhages, in patients on oral anticoagulants or dual antiplatelet therapy. We hypothesized that there may be an association of GDF-15 with incidence of hemorrhagic strokes in the general population, which has not been investigated be

Review of Anna-Maija Multas PhD thesis from 2022: New health information literacies. A nexus analytical study. Acta universitatis OuluensisB Humaniora 192, University of Oulu, Oulu

Convection-enhanced delivery as a means to deliver therapeutic drugs directly to the brain has shown limited clinical efficacy, primarily attributed to the phenomena of backflow, in which the infused fluid flows preferentially along theshaft catheter rather than forward into the tissue. We have previously developed a finite element model of backflow that includes both material and geometric nonlin

Human in vitro models of neural tissue with tunable microenvironment and defined spatial arrangement are needed to facilitate studies of brain development and disease. Towards this end, embedded printing inside granular gels holds great promise as it allows precise patterning of extremely soft tissue constructs. However, granular printing support formulations are restricted to only a handful of ma

Based on solid evidence, mesh prosthesis reinforcement has reduced the risk of recurrence after umbilical hernia repair1–4, but less is known about the risk of complications or chronic pain4,5. Patients’ claims after surgery may represent a surrogate for poor outcome6. This study examined mesh prosthesis-related complications leading to economic compensation after elective umbilical hernia repair.

Background: Delayed cerebral ischemia (DCI), a complication of subarachnoid hemorrhage (SAH), is linked to cerebral vasospasm and associated with poor long-term outcome. We implemented a structured cerebral microdialysis (CMD) based protocol using the lactate/pyruvate ratio (LPR) as an indicator of the cerebral energy metabolic status in the neurocritical care decision making, using an LPR ≥ 30 as

This study analyzes the relationship of having a child with the early-onset disability cerebral palsy (CP) and the parental decision to divorce and to have additional children. We use longitudinal matched case-control data from multiple linked Swedish National Population Registers between 2001 and 2015 and perform Cox proportional hazards regressions with interval-censoring. Although we do not fin