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Polarity and growth directions in Sn-seeded GaSb nanowires

We here investigate the growth mechanism of Sn-seeded GaSb nanowires and demonstrate how the seed particle and its dynamics at the growth interface of the nanowire determine the polarity, as well as the formation of structural defects. We use aberration-corrected scanning transmission electron microscopy imaging methodologies to study the interrelationship between the structural properties, i.e. p

Vectorial Hankel operators, Carleson embeddings, and notions of BMOA

Let (Formula presented.) denote the space of (Formula presented.)-valued analytic functions (Formula presented.) for which the Hankel operator (Formula presented.) is (Formula presented.)-bounded. Obtaining concrete characterizations of (Formula presented.) has proven to be notoriously hard. Let (Formula presented.) denote fractional differentiation. Motivated originally by control theory, we char

Tyrosine 842 in the activation loop is required for full transformation by the oncogenic mutant FLT3-ITD

The type III receptor tyrosine kinase FLT3 is frequently mutated in acute myeloid leukemia. Oncogenic FLT3 mutants display constitutive activity leading to aberrant cell proliferation and survival. Phosphorylation on several critical tyrosine residues is known to be essential for FLT3 signaling. Among these tyrosine residues, Y842 is located in the so-called activation loop. The position of this t

A healthier US diet could reduce greenhouse gas emissions from both the food and health care systems

The standard US diet contributes to greenhouse gas emissions (GHGE) from both the food system, and from the health system through its contribution to non-communicable diseases. To estimate the potential for diet change to reduce GHGE and improve public health, we analyzed the effect of adopting healthier model diets in the USA on the risk of disease, health care costs, and GHGE. We found that adop

On Locating Value in Making Moral Progress

The endeavour to locate value in moral progress faces various substantive as well as more formal challenges. This paper focuses on challenges of the latter kind. After some preliminaries, Section 3 introduces two general kinds of “evaluative moral progress-claims”, and outlines a possible novel analysis of a (quasi) descriptive notion of moral progress. While Section 4 discusses certain logical fe

Searching for a middle ground : anthropologists and the debate on the universalism and the cultural relativism of human rights

In the anthropological debate on human rights a new theoretical approach, a search for a middle ground, has been attempted to solve the dilemma of universalism versus cultural relativism. In the human rights discussion in general, and in the anthropological debate in particular, the dichotomy of universalism/relativism is seen as one major obstacle to the implementation. This article takes a criti

Genetic and regulatory mechanism of susceptibility to high-hyperdiploid acute lymphoblastic leukaemia at 10p21.2

Despite high-hyperdiploid acute lymphoblastic leukaemia (HD-ALL) being the most common subgroup of paediatric ALL, its aetiology remains unknown. Genome-wide association studies have demonstrated association at 10q21.2. Here, we sought to determine how this region influences HD-ALL risk. We impute genotypes across the locus, finding the single nucleotide polymorphism rs7090445 highly associated wi

Search for dark matter at colliders

Among the numerous proposals to explain the nature of dark matter, there is the weakly interacting massive particle (WIMP) scenario, which is based on a simple assumption that dark matter was in thermal equilibrium in the early hot Universe, and its particles have mass and interactions not too different from the massive particles in the standard model. In this Progress Article we overview the infe

Sequential Proton-Coupled Electron Transfer Mediates Excited-State Deactivation of a Eumelanin Building Block

Skin photoprotection is commonly believed to rely on the photochemistry of 5,6-dihydroxyindole (DHI)- and 5,6-dihydroxyindole-2-carboxylic acid (DHICA)-based eumelanin building blocks. Attempts to elucidate the underlying excited-state relaxation mechanisms have been partly unsuccessful due to the marked instability to oxidation. We report a study of the excited-state deactivation of DHI using ste

Ultrafast Time-Resolved X-ray Absorption Spectroscopy of Ferrioxalate Photolysis with a Laser Plasma X-ray Source and Microcalorimeter Array

The detailed pathways of photoactivity on ultrafast time scales are a topic of contemporary interest. Using a tabletop apparatus based on a laser plasma X-ray source and an array of cryogenic microcalorimeter X-ray detectors, we measured a transient X-ray absorption spectrum during the ferrioxalate photoreduction reaction. With these high-efficiency detectors, we observe the Fe K edge move to lowe

Targeted Proteomics Approach for Precision Plant Breeding

Selected reaction monitoring (SRM) is a targeted mass spectrometry technique that enables precise quantitation of hundreds of peptides in a single run. This technique provides new opportunities for multiplexed protein biomarker measurements. For precision plant breeding, DNA-based markers have been used extensively, but the potential of protein biomarkers has not been exploited. In this work, we d

Irreversible Kidney Damage due to Multicentric Castleman's Disease

Castleman's Disease (CD) is a rare lymphoproliferative disorder accompanied by marked systemic inflammatory response. Morphological diagnosis of CD requires biopsy of the whole of the involved lymph node tissue. Three histologic variants have already been described in CD morphology (hyaline vascular, plasma-cell, and mixed). In this study, we report a case of a multicentric Castleman's disease of

Male Experiences of Life After Recovery From an Eating Disorder

The aim of this study was to describe how former male patientsperceive life after recovery from an eating disorder. A qualitativemethod with a phenomenographic approach was used toidentify ways of experiencing recovery. Two descriptive categorieswere developed: body acceptance and self-worth. Six conceptionsdescribe how recovered patients now relate in a balanced way toexercise and food, using strThe aim of this study was to describe how former male patients perceive life after recovery from an eating disorder. A qualitative method with a phenomenographic approach was used to identify ways of experiencing recovery. Two descriptive categories were developed: body acceptance and self-worth. Six conceptions describe how recovered patients now relate in a balanced way to exercise and food, usi

Supply Chain Risk Management : En modell för riskbedömning och riskhantering

Dagens moderna samhälle är ett i många avseenden sårbart samhälle. Det har inte varit någon medveten strävan utan är en konsekvens av att samhället till stor del kommit att bli uppbyggt kring försörjningskedjor (supply chains). I dessa hårt integrerade kedjor med ett flertal ofta globalt utspridda led flyter en ständig ström av fysiska varor, tjänster samt kombinationer av varor och tjänster.Det e