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Characterization of ventricular depolarization and repolarization changes in a porcine model of myocardial infarction

In this study, several electrocardiogram (ECG)-derived indices corresponding to both ventricular depolarization and repolarization were evaluated during acute myocardial ischemia in an experimental model of myocardial infarction produced by 40 min coronary balloon inflation in 13 pigs. Significant changes were rapidly observed from minute 4 after the start of coronary occlusion, achieving their ma

Linking landscape history and dispersal traits in grassland plant communities

Dispersal limitation and long-term persistence are known to delay plant species’ responses to habitat fragmentation, but it is still unclear to what extent landscape history may explain the distribution of dispersal traits in present-day plant communities. We used quantitative data on long-distance seed dispersal potential by wind and grazing cattle (epi- and endozoochory), and on persistence (adu

Inter-market variability in CO2 emission-intensities in tourism: Implications for destination marketing and carbon management

There is a growing gap between tourism's rapidly growing greenhouse gas emissions and the sector's 'aspirational' emission reduction targets as well as the international policy consensus to reduce emissions from this and all other sectors of the economy. The transport component is the largest GHG contributor to the global tourism system. In the absence of supranational policy agreements to curb em

Fabrication of high aspect ratio SU-8 micropillar arrays

SU-8 is the preferred photoresist for development and fabrication of high aspect ratio (HAR) three dimensional patterns. However, processing of SU-8 is a challenging task, especially when the film thickness as well as the aspect ratio is increasing and the size of the features is close to the resolution limit of photolithography. This paper describes process optimization for the fabrication of den

Measurements of Elliptic and Triangular Flow in High-Multiplicity He-3 + Au Collisions at root s(NN)=200 GeV

We present the first measurement of elliptic (v(2)) and triangular (v(3)) flow in high-multiplicity He-3 + Au collisions at root s(NN) = 200 GeV. Two-particle correlations, where the particles have a large separation in pseudorapidity, are compared in He-3 + Au and in p + p collisions and indicate that collective effects dominate the second and third Fourier components for the correlations observe

From Perspectives to Policy Contingencies: conditional cash transfers as social investments

Despite the popularity of the social investment approach, there remain ambiguities regarding how to design an effective social investment policy. We review evaluations of conditional cash transfers (CCTs) in Latin America in order to draw out lessons for how to improve the effectiveness of social investment. CCTs share many of the objectives of the social investment approach and are targeted at po

Determination of 21-hydroxylase autoantibodies: inter-laboratory concordance in the Euradrenal International Serum Exchange Program

Background: 21-Hydroxylase autoantibodies (21OHAb) are markers of an adrenal autoimmune process that identifies individuals with autoimmune Addison's disease (AAD). Quality and inter-laboratory agreement of various 21OHAb tests are incompletely known. The objective of the study was to determine inter-laboratory concordance for 21OHAb determinations. Methods: Sixty-nine sera from 51 patients with A

Chiral-symmetric technicolor with standard model Higgs boson

Most of the traditional technicolor-based models are known to be in a strong tension with the electroweak precision tests. We show that this serious issue is naturally cured in strongly coupled sectors with chiral-symmetric vectorlike gauge interactions in the framework of the gauged linear sigma model. We discuss possible phenomenological implications of such a nonstandard chiral-symmetric techni

Measurement of the production cross section of prompt j/psi mesons in association with a W (+/-) boson in pp collisions root s=7 TeV with the ATLAS detector

The process pp -> W (+/-) J/psi provides a powerful probe of the production mechanism of charmonium in hadronic collisions, and is also sensitive to multiple parton interactions in the colliding protons. Using the 2011 ATLAS dataset of 4.5 fb(-1) of root s= 7 TeV pp collisions at the LHC, the first observation is made of the production of W (+/-) + prompt J/psi events in hadronic collisions, using

Outcome of Ischemic Foot Ulcer in Diabetic Patients Who Had no Invasive Vascular Intervention.

OBJECTIVE/BACKGROUND: There is limited information regarding outcome in patients not available for revascularisation. Our aim was to identify factors related to ulcer healing in diabetic patients with severe peripheral arterial disease who were not available for revascularisation. METHODS: Diabetic patients with a foot ulcer, consecutively presenting at a multidisciplinary foot centre with systoli

Levodopa--carbidopa intestinal gel for treatment of advanced Parkinson''s disease

Levodopa is the mainstay of Parkinson''s disease (PD) treatment, but is often eventually associated with disabling motor complications in patients with advanced PD. The inability of perorally administered levodopa to provide more physiologic continuous dopaminergic stimulation (CDS) is a leading hypothesis to explain these complications. To investigate the cumulative efficacy and safety, and re-ev

CspA from Borrelia burgdorferi Inhibits the Terminal Complement Pathway

In order to survive and persist in an immunocompetent human host, Borrelia burgdorferi controls the human immune attack and blocks the damaging effects of the activated complement system. These Gram-negative spirochetes use CspA (CRASP-1) and four additional immune evasion proteins to bind combinations of human plasma regulators, including factor H, factor H-like protein 1 (FHL-1), complement fact

Supercritical fluid extraction of lipids from linseed with on-line evaporative light scattering detection.

Supercritical fluid extraction (SFE) is a green alternative method of extraction for neutral lipids in seeds compared to conventional methods utilizing organic solvents. In this work, a novel method where SFE is hyphenated with an evaporative light scattering detector is presented. The method was subsequently applied to determine lipid content in crushed linseed. The new method enables rapid quant

Heparan sulfate proteoglycan as a cell-surface endocytosis receptor.

How various macromolecules are exchanged between cells and how they gain entry into recipient cells are fundamental questions in cell biology with important implications e.g. non-viral drug delivery, infectious disease, metabolic disorders, and cancer. The role of heparan sulfate proteoglycan (HSPG) as a cell-surface receptor of diverse macromolecular cargo has recently been manifested. Exosomes,