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Palmitate-induced beta-cell dysfunction is associated with excessive NO production and is reversed by thiazolidinedione-mediated inhibition of GPR40 transduction mechanisms.

BACKGROUND: Type 2 diabetes often displays hyperlipidemia. We examined palmitate effects on pancreatic islet function in relation to FFA receptor GPR40, NO generation, insulin release, and the PPARgamma agonistic thiazolidinedione, rosiglitazone. PRINCIPAL FINDINGS: Rosiglitazone suppressed acute palmitate-stimulated GPR40-transduced PI hydrolysis in HEK293 cells and insulin release from MIN6c cel

Improved hand function in a dental hygienist with neuropathy induced by vibration and compression: The effect of cutaneous anaesthetic treatment of the forearm.

We report a case of neuropathy induced by vibration and compression in the hand of a dental hygienist. Her hand function was improved considerably by repeated treatment during which EMLA(R) cream (EMLA(R) cream is a local anaesthetic agent containing lidocain 2.5% and priolocain 2.5%) was applied to the forearm to induce cutaneous anaesthesia.

Polynomial Solvers for Geometric Problems - Applications in Computer Vision and Sensor Networks

Given images of a scene taken by a moving camera or recordings of a moving smart phone playing a song by a microphone array, how hard is it to reconstruct the scene structure or the moving trajectory of the phone? In this thesis, we study and solve several fundamental geometric problems in order to provide solutions to these problems. The key underlying technique for solving such geometric probl

Observing and influencing preferences in real time. Gaze, morality and dynamic decision-making

Preference formation and choice are dynamic cognitive processes arising from interactions between decision-makers and their immediate choice environment. This thesis examines how preferences and decisions are played out in visual attention, captured by eye-movements, as well as in group contexts. Papers I-II make use of the Choice Blindness paradigm. Paper I compares participants’ eye movements

Some rate 1/3 and 1/4 binary convolutional codes with an optimum distance profile

A tabulation of binary systematic convolutional codes with an optimum distance profile for rates1/3and1/4is given. A number of short rate1/3binary nonsystematic convolutional codes are listed. These latter codes are simultaneously optimal for the following distance measures: distance profile, minimum distance, and free distance; they appear attractive for use with Viterbi decoders. Comparisons wit

Strategic management - An online collaboration between two class groups separated by a "small pond" and six time zones

An undergraduate course in Strategic Management seemingly provides similar basic content to students including the infamous SWOT (strengths, weaknesses, opportunities and threat) analysis along with the identification of functional level, business level, and generic strategies to enhance an organization’s competitiveness. One of the most common resources for this type of course is the article outl

Optical spectroscopy of turbid media: time-domain measurements and accelerated Monte Carlo modelling

Popular Abstract in Swedish Denna avhandling handlar om optisk spektroskopi, d.v.s. att med hjälp av ljus best ̈mma fysiska och kemiska egenskaper hos ett prov. När ljus interagerar med atomer och molekyler absorberas endast ljus av vissa våglängder (färger). Exakt vilka färger som absorberas är unikt för varje sorts atom eller molekyl och utgör alltså ett sorts ”fingeravtryck”. Genom att noggranOptical spectroscopy is a versatile and powerful tool to probe translucent materials. In this work, the focus is on characterization of strongly scattering (turbid) materials by means of time-of-flight spectroscopy (TOFS). Instrumentation and modelling aspects of TOFS were investigated and improved, enabling significantly more accurate spectroscopic measurements. It was shown that the commonly us

Microsatellite primers in the planktonic diatom Pseudo-nitzschia multistriata (Bacillariophyceae)

Premise of the study: Seven microsatellite loci were characterized for the toxic diatom Pseudo-nitzschia multistriata Takano (Takano) to investigate intraspecific variability and estimate population genetic structure over blooms, seasons, and sexual and vegetative reproduction. Methods and Results: Selected microsatellites consisted of di- and trinucleotide repeats in the core region, and showed

Microfluidics Separation and Analysis of Biological Particles

Popular Abstract in Swedish Hoppet väcks för sömnsjuka Det sticker till i benet. Du viftar med handen, men alltför långsamt. Du ser en glimt av den ljusbruna flugan, stor som ett bi, och hör hur den surrar vidare genom den varma afrikanska eftermiddagen mot sitt nästa blodmål. Tsetseflugans bett kliar. Inom ett par dagar har det förvandlats till en arg röd svullnad. Därinne förökar sig parasiternIn the last decade, powerful communication and information technology in the form of the mobile phone has been put into the hands of more than 50% of the global population. In stark contrast, a lack of access to medical diagnostic technology with which to diagnose both communicable and non-communicable diseases will mean that many of these people will die of easily treatable conditions. Small, por

Proximity-based reminders using Bluetooth

A smartphone is a personal device and as such usually hosts multiple public user identities such as a phone number, email address, and Facebook account. As each smartphone has a unique Bluetooth MAC address, Bluetooth discovery can be used in combination with the user registration to a server with a Facebook account. This makes it possible to identify a nearby smartphone related to a given Faceboo