Genetic alterations, such as p53 mutations, may affect a tumour's response to chemotherapy. We have treated two human breast cancer cell lines that differ in p53 status with epirubicin in order to study if there are differences in cell cycle kinetic response. MCF-7 cells express wild-type p53, while SK-BR-3 cells express only a mutated form of p53. The transition of cells from one cell cycle stage

In recent years global problems such as climatic change, acid rain, and water pollution in surface and subsurface environments dominate discussions of world environmental problems. In this paper, the roles of hydrologic processes and hydrogeochemical processes are investigated through development, modification, and application of mathematical models for addressing point and non-point source water

Aim To identify the effect of climate change on selected plant species representative of the main vegetation types in the Faroe Islands. Due to a possible weakening of the North Atlantic Current, it is difficult to predict whether the climate in the Faroe Islands will be warmer or colder as a result of global warming. Therefore, two scenarios are proposed. The first scenario assumes an increase in

Recension av Allan A. Lund, Mumificerede moselig.

PURPOSE: The frequency of activated protein C (APC) resistance, caused by factor V R506Q gene mutation and abnormal APC ratio, in patients with peripheral vascular diseases was analyzed. METHODS: All patients electively admitted to the vascular ward unit of our tertiary care academic medical center from January 1995 through October 1996 (n = 679) were prospectively analyzed using an APC-resistance

We consider wireless systems with transmit and receive diversity. For reduction of complexity, we propose to use hybrid selection/maximal-ratio transmission at one link end, choosing L out of N antennas. We analyze the performance of such systems, giving analytical bounds and comparing them with computer simulations. Outage probability, symbol error probability, and capacity are shown. We demonstr

This thesis emphasises the role of commercial banks as financial intermediaries. It is primarily concerned with the development of the commercial banking system of Lebanon in the period 1856-1974, and assesses the role of the commercial banking system in Lebanon, as capital provider to economic development. This role is examined here in terms of the mobilisation of bank deposits and allocation of

A new method for extracting respiratory signals from the ECG/VCG is presented. The method is based on the alignment of an observed VCG loop to a reference loop with respect to the transformations of rotation and time synchronisation. The resulting series of estimated rotation angles reflects respiratory-induced changes in the electrical axis of the heart. The respiratory frequency is estimated by

Background: The availability of high throughput methods for measurement of mRNA concentrations makes the reliability of conclusions drawn from the data and global quality control of samples and hybridization important issues. We address these issues by an information theoretic approach, applied to discretized expression values in replicated gene expression data. Results: Our approach yields a quan

Popular Abstract in Swedish Stroke utgör den tredje vanligaste dödsorsaken i västvärlden och är dessutom huvudorsak till långvarigt handikapp hos vuxna individer. Det stora antalet överlevande men handikappade individer utgör ett omfattande problem för samhället inte bara i form av ekonomiska resurser utan även vad gäller personliga trauma. Den kliniska termen stroke omfattar patologiska tillståndStroke is the most common life-threatening neurological disease and ranks as the third leading cause of death in major industrialized countries. It is also the leading cause of serious long-term disability and about sixty percent of survivors have disabilities in their extremities. Recovery of certain neurological functions occurs over time, which has been attributed to endogenous restorative proc

Objective. We recently showed that plasma concentration of N-terminal atrial natriuretic peptide (Nt-proANP) is strongly directly related to salt sensitivity. The aims of the present study were to test (i) whether plasma concentration of N-terminal brain natriuretic peptide (Nt-proBNP) is related to salt sensitivity and (ii) whether Nt-proANP, as a marker of salt sensitivity, differs between type

We aimed to study the occurrence of emphysematous lesions in symptom free smoking men of about 60 years of age and in a matching group of never-smoking men and the relationship between pulmonary changes at high resolution computed tomography (HRCT) and lung function tests. Our investigation included 57 smoking and 32 never-smoking healthy men from a randomized epidemiological study. HRCT was perfo

Objectives. To compare perinatal and infant mortality in breech and cephalic presentations and between planned vaginal and cesarean section (CS) breech deliveries in Sweden. Methods. The study comprised two parts. Study A is a national cohort study for the period 1991-2001, including 22 549 breech presentations and 875 249 cephalic presentations born at >= 38 completed weeks. Study B is a case-con

Amperometric screen-printed biosensor arrays for detection of pesticides (organophosphates and carbamates) and phenols have been developed. Cholinesterases (AChE and BChE), tyrosinase (TYR), peroxidases (SBP. soybean and HRP. horseradish) and cellobiose dehydrogenase (CDH) were combined on the same array consisting of one Ag/AgCl reference electrode surrounded by eight radially distributed working