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BACKGROUND: Cancer-associated fibroblasts (CAFs) are molecularly heterogeneous mesenchymal cells that interact with malignant cells and immune cells and confer both anti- and pro-tumorigenic functions. Prior in situ profiling studies of human CAFs have largely relied on scoring single markers, thus presenting a very limited view of their molecular complexity. Our objective was to study the complex

Background and aim: Allergic asthma is a complex inflammatory disease involving type 2 innate lymphoid cells, type 2 T helper cells, macrophages, and eosinophils. The disease is characterized by wheezing, dyspnea, coughing, chest tightness and variable airflow limitation for which there is no cure and is symptomatically treated with inhaled corticosteroids and β2-agonists. Molecular mechanisms und

Despite the relatively uncontested importance of promoting school attendance in the policy arena, little evidence exists on the causal effect of school absence on long-run outcomes. We address this question by combining historical and administrative records for cohorts of Swedish individuals born in the 1930s. We find that elementary school absence significantly reduces contemporaneous academic pe

This study analyzes how risk attitudes influence the agricultural productivity of men and women in a sub- Saharan African country, Burkina Faso. By using a large representative panel survey of farmers, the results show that as female farmers increase risk taking, the productivity of female-owned plots goes down. The study controls for various socio-economic factors and explores how the diversity oThis study analyzes how risk attitudes influence the agricultural productivity of men and women in a sub- Saharan African country, Burkina Faso. By using a large representative panel survey of farmers, the results show that as female farmers increase risk taking, the productivity of female-owned plots goes down. The study controls for various socio-economic factors and explores how the diversity o

Black carbon (BC), spheroidal carbonaceous particles (SCP), and polycyclic aromatic hydrocarbons (PAH) are carbonaceous pollutants affecting the climate, environment, and human health. International regulations limit their emissions, and the present emissions are followed by monitoring programs. However, the monitoring programs have limited spatio-temporal coverage and only span the last decades.

In recent years there has been a renewed interest in subnational levels of governance as sites of potential and renewed ambition on climate change. One recent challenge to dominant neoliberal discourses of climate governance is legislation enacted in Wales, which places sustainable development as the central organising principle of local government. Through a Critical Discourse Analysis, supplemen

This article furthers political geographic thinking on democracy by generating and employing a conceptualisation of ‘assemblage-democracy’. Bringing an assemblage perspective to democratic thinking brings to the fore three key dimensions: the co-constitution of material and non-material connections; connectivity and associations, in particular engagement with multiple heterogeneous ‘minoritarian’

‘Green’ forms of finance are deemed increasingly important in mitigating climate change. Despite growing calls to make financial flows consistent with Paris Agreement goals, to date little is known about the impact of ‘green finance’. Drawing on literature which explores how resources are assembled for investment, this research shifts the focus from financial flows to financial pools. It does so t

Private investment capital is now widely regarded as strategically significant to the governance of climate change. A dedicated and dynamic carbon finance sector has emerged that features techniques and practices for decarbonizing capital, facilitating investment in low-carbon projects and enterprises or enabling divestment from high-carbon firms and sectors. We bring together and develop the conc

Calls for greater 'energy democracy' foresee a greater role for voluntary sector activity - including through community groups' ownership of energy projects - to help produce more open, participatory and just energy systems. This article offers a novel conceptualisation of democracy through viewing community energy projects as assemblages of heterogeneous elements, and traces their enlacement with

Growing emphasis on finance as key to decarbonization requires social science research that critically attends to the emergent and diverse forms taken by carbon finance. First, we pluralize research into carbon finance, building on existing work to identify four main forms: carbon markets; ecosystem services; natural capital investment; and, capital allocated to low-carbon enterprises and projects

The distributed nature of renewable energy has given rise to new forms and scales of energy governance, in particular the emerging role of households and community organisations in generating and distributing renewable energy. Accompanying this trend has been the emergence of intermediary organisations, whose role it is to mediate between these actors cf. the market and the state, with the aim to