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Phorbol esters promote α1-adrenergic receptor phosphorylation and receptor uncoupling from inositol phospholipid metabolism

DDT1 MF-2 cells, which are derived from hamster vas deferens smooth muscle, contain α1-adrenergic receptors (54,800 ± 2700 sites per cell) that are coupled to stimulation of inositol phospholipid metabolism. Incubation of these cells with tumor-promoting phorbol esters, which stimulate calcium- and phospholipid-dependent protein kinase, leads to a marked attenuation of the ability of α1-receptor a

Three new genera of the Ramalinaceae (lichen-forming Ascomycota) and the phenomenon of presence of ‘extraneous mycobiont DNA’ in lichen associations

Three new genera Coppinsidea, Vandenboomia and Wolseleyidea are described and the genera Ivanpisutia, Lecaniella and Myrionora are resurrected on the basis of a phylogenetic analysisof multi-locus sequence data of the Ramalinaceae including the nuclear protein-codingmarker rpb2, the internal transcribed spacer and a fragment of the small mitochondrialsubunit. The genus Hertelidea was positioned wi

METHOD FOR THERMAL TREATMENT OF TALL OIL PITCH (TOP)

The present invention describes a method for the treatment of tall oil pitch (TOP), said method comprising heating the TOP and optionally additives including water and steam to a temperature of at least 300°C; maintaining the temperature in the reactor at 300°C or higher for a period of time to enable thermal treatment of the TOP to act on components thereof toproduce fatty acids and/or rosin acid

Impacts of increasing aridity and wildfires on aerosol loading in the intermountain Western US

Feedbacks between climate warming, land surface aridity, and wildfire-derived aerosols represent a large source of uncertainty in future climate predictions. Here, long-term observations of aerosol optical depth, surface level aerosol loading, fire-area burned, and hydrologic simulations are used to show that regional-scale increases in aridity and resulting wildfires have significantly increased

Development of a harmonised soil profile analytical database for Europe : A resource for supporting regional soil management

Soil mapping is an essential method for obtaining a spatial overview of soil resources that are increasingly threatened by environmental change and population pressure. Despite recent advances in digital soil-mapping techniques based on inference, such methods are still immature for large-scale soil mapping. During the 1970s, 1980s and 1990s, soil scientists constructed a harmonised soil map of Eu

Repair and Reconstruction of Peripheral Nerve Injuries. Treatment with G-CSF and Stromal Vascular Fraction.

While surgery is a cornerstone in treatment of peripheral nerve injuries, it is not a comprehensive approach, and outcome is unsatisfactory, especially sensory function. The present aim was to translate recent findings about stem- and progenitor cells to improve regenerative outcome, where the cells have to be autologous, available within the same surgical procedure, and minimally manipulated. Gra

Puzzling out the choice of capital budgeting techniques : Among high-growth small and medium sized firms

The aim of this dissertation is to explore the drivers of practitioners’ choices of capital budgeting techniques (CBT). The mainstream literature suggests that sophisticated CBT (SCBT) will best guide organizations in evaluating important strategic investments. Small and medium-size enterprises (SMEs) choose to go against that “wisdom” and choose non-sophisticated CBT (NSCBT).Instead of following The aim of this dissertation is to explore the drivers of practitioners’ choices of capital budgeting techniques (CBT). The mainstream literature suggests that sophisticated CBT (SCBT) will best guide organizations in evaluating important strategic investments. Small and medium-size enterprises (SMEs) choose to go against that “wisdom” and choose non-sophisticated CBT (NSCBT). Instead of following

Artificial Intelligence for Aortic Pressure Waveform Analysis During Coronary Angiography : Machine Learning for Patient Safety

Objectives: This study developed a neural network to perform automated pressure waveform analysis and allow real-time accurate identification of damping. Background: Damping of aortic pressure during coronary angiography must be identified to avoid serious complications and make accurate coronary physiology measurements. There are currently no automated methods to do this, and so identification of

Material reuse in buildings : Implications of a circular business model for sustainable value creation

Buildings are responsible for a third of global greenhouse gas emissions. A large proportion of their life cycle impacts derives from emissions embedded in materials. Material reuse has the potential to reduce these embedded impacts, since reused materials often have smaller environmental footprints than primary materials. Institutional settings and the structure of the building sector pose multip

Assessing performance of supply chain risk management programmes : A tentative approach

This exploratory study provides initial directions about how risk management programmes could be assessed in a supply chain setting and discusses how such a measurement system could be designed. Measures are needed both for the management to evaluate the success of actions taken in supply chain risk management, as well as for the (supply chain) risk manager to communicate the value of his work. A

Gaining hope and self-confidence - An interview study of women's experience of treatment by art therapy for severe fear of childbirth

BACKGROUND: Fear of childbirth is a serious problem that can have negative effects on both women and babies and to date treatment options are limited. The aim of this study was to elucidate the experience of undergoing art therapy in women with severe fear of childbirth.METHOD: Nineteen women residing in Sweden, who had undergone art therapy for severe fear of childbirth, were interviewed during 2

Refractive error and glaucoma

Purpose: To study the association between refractive error, glaucoma damage and IOP in a large population. Methods: We examined 32,918 citizens of the city of Malmö, Sweden, 57-79 years of age, searching for individuals with undetected glaucoma. Refraction was measured with autorefractors. Glaucoma damage was defined as reproducible visual field defects with the Humphrey Full Threshold 24-2 progra