We describe a new method for quantitatively measuring substances of clinical interest by high-performance liquid affinity chromatography (HPLAC). As a model system we selected analysis for transferrin in human serum with immobilized antibodies in a high-performance liquid chromatographic system. SelectiSpher-10 Activated Tresyl columns (5 or 10 x 0.5 cm) were used for in situ coupling of polyc

A new type of support for chromatographic use has been developed. Non-porous quartz fibre, with a mean diameter of 0.5 μm, was silylated with mercaptopropyltrimethoxysilane. Tresyl chloride-activated dextran was covalently coupled to the SH groups on the fibre. Remaining active tresyl groups on the dextran were then coupled with an NAD derivative.The affinity fibre contained 0.3 μmol NAD derivativ

A screening of immobilized α-chymotrypsin preparations suitable for the synthesis of N-acetyl-L-tyrosine ethyl ester from N-acetyl-L-tyrosine and up to 99% ethanol was carried out. α-Chymotrypsin adsorbed to Sepharose LH-20 or covalently bound to Sepharose 4B (tresyl chloride activation) was found to be an efficient catalyst. A column packed with immobilized enzyme retained 60% of its initial acti

We chart and assess the scope and utilisation of government-provided hospital infrastructure in British Africa, c. 1900-1960. Using various archival sources, we examine the heterogeneity in colonial administrations’ investment into curative healthcare provision across various regions of British Africa. Our research highlights significant disparities in healthcare provision during the colonial peri

Södervärns vattentorn är kanske en av Malmös mest kända byggnader. Sen det stod klart 1916 och fram tills det togs ur bruk 2015 har det försett Malmö­iterna­ med dricksvatten. Efter tornet slutat att användas som vattentorn har en debatt hållits kring vad som skall ske med tornet utan resultat. Detta examensarbete svarar på denna fråga baserat på en analys av byggnaden och ett gestaltningsförslag Södervärn’s water tower is probably one of Malmö’s most iconic building. Since its construction in 1916 and until it was taken out of use in 2015 it has provided the citizens of Malmö with drinking water. Ever since the decicion to exlcude the tower as a part of the city’s water system, a debate has been held on what shall become of the tower, without leading to any decisive decisions. This thesis

“Buildings, more often than not, outlast civilizations” skrev Kenneth Powell i sin bok Architecture Reborn. För många kan denna mening ses som självklar, eftersom vi betraktar byggnader som något som kommer att stå i flera hundra år. Men om vi kollar på verkligheten, är det inte alltid fallet. Man kan undra varför vi river byggnader. Var där något fel på byggnaden? Var den inte livsduglig, inte u“Buildings, more often than not, outlast civilizations”, Kenneth Powell wrote in Architecture Reborn. For many this may seem obvious, as we presume buildings will stand for hundreds of years. But if we look into reality, this is not always the case. One may ask why buildings are demolished. Was there something wrong with the building? Was it not viable, not valued by its users, not thought-throug

BACKGROUND: Allergic contact dermatitis (ACD) from protective gloves is often caused by rubber additives, such as accelerators. However, while accelerator-free rubber gloves are available, they still cause ACD in some individuals.OBJECTIVES: A new allergen, 2-cyаnоethyl dimethyldithiocarbamate, (CEDMC), has recently been identified in accelerator-free gloves, and we here provide a first in vitro c

BIRDS THAT SPEND the winter in a harsh and cold climate face a suite of challenges that require optimization of energy expenditure and energy intake. Some birds roost communally, which can increase energy savings during cold winter nights. However, this behaviour is almost completely absent in chickadees, tits, and titmice (Paridae) as there are very few accounts in the literature of parids roosti

INTRODUCTION: The recent introduction of seed amplification assays (SAAs) detecting misfolded α-synuclein, a pathology-specific marker for Lewy body disease (LBD), has allowed the in vivo identification and phenotypic characterization of patients with co-occurring Alzheimer's disease (AD) and LBD since the early clinical or even preclinical stage. METHODS: We reviewed studies with an in vivo bioma

This paper presents an overview of the literature on universal design for equitable healthcare. The central inquiry in the current paper is a critical design-for-all challenge: how might universal design contribute to providing equitable healthcare for women suffering from pelvic floor injuries during birth? This study delves into some of the explicit and implicit needs of this deprioritized minorThis paper presents an overview of the literature on universal design for equitable healthcare. The central inquiry in the current paper is a critical design-for-all challenge: how might universal design contribute to providing equitable healthcare for women suffering from pelvic floor injuries during birth? This study delves into some of the explicit and implicit needs of this deprioritized minor

For young people, a first encounter with criminal justice can have lasting effects. While perceptions of equitable treatment can generate feelings of belongingness and acceptance, treatment perceived as unfair or prejudicial can generate experiences of dissonance and exclusion. However, little research has examined young people’s appraisals of justice system encounters. The purpose of the study wa

High performance powder-based Ni-based superalloys exhibit exceptional in-service properties at elevated temperature, however this leads to reduced machinability and the potential for significant machining induced damage. Field assisted sintering technology (FAST) is capable of consolidating powder rapidly and efficiently, allowing for precise control of the microstructure via the dissolution of s

We extend and strengthen a theorem of Bates that says that row-finite graphs that are strong shift equivalent have Morita equivalent graph C*-algebras. This allows us to ask whether our stronger notion of Morita equivalence does in fact characterise strong shift equivalence. We believe this will be relevant for future research on infinite graphs and their C*-algebras. We also study in-splits and o

Background: Body dysmorphic disorder (BDD) is thought to be associated with considerable suicide risk. This nationwide cohort study quantified the risks of intentional self-harm—including nonsuicidal self-injuries and suicide attempts—and death by suicide in BDD. Methods: Individuals with a validated ICD-10 diagnosis of BDD in the Swedish National Patient Register, registered between January 1, 19

From back cover: "A smart, incisive toolkit for understanding how the framing of information influences the way we see the world.In today's chaotic media landscape, working out who and what to believe is a daunting task. Lies and misinformation are only part of the problem - often the way a story is presented has just as much effect on us as what the story is.In Framing, sociologist Mikael Klintma

Non-revenue water due to pipe leakages presents a significant global challenge, impacting both the economy and environmental sustainability. The current approach to pipe management for water utilities in Sweden is mainly reactive; leaks are repaired when detected, sometimes with large costs if the leakage is extensive and critical. With this study, we want to focus on proactive pipe network manage