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Particulate matter constituents trigger the formation of extracellular amyloid β and Tau -containing plaques and neurite shortening in vitro

Air pollution is an environmental factor associated with an increased risk of neurodegenerative diseases, such as Alzheimer’s and Parkinson’s, characterized by decreased cognitive abilities and memory. The limited models of sporadic Alzheimer’s disease fail to replicate all pathological hallmarks of the disease, making it challenging to uncover potential environmental causes. Environmentally drive

Effekter av naturbaserade interventioner i allmänna miljöer - i relation till stressrelaterad ohälsa.

Bakgrund: Naturen har potentiellt positiv effekt på mental hälsa, vilket kan användas inom rehabilitering. Forskning har bedrivits på ämnet inom psykologi, landskapsarkitektur och stadsplanering. Det finns studier som undersöker naturbaserade interventioners (NBI) effekter i rehabiliteringsträdgård, men inte av NBI förlagd i allmän miljö. Syfte: Syftet är att kartlägga innehåll, genomförande och eBackground: Nature's potentially positive effect on human health may be used for rehabilitation purposes. This is researched in the field of psychology, landscape planning and urban planning. There are studies of the effect of nature-based interventions (NBI) located in rehabilitation gardens, but not of NBI in public nature-environments. Aim: to survey the content, implementation and effects

Measurement of the VH,H → ττ process with the ATLAS detector at 13 TeV

A measurement of the Standard Model Higgs boson produced in association with a W or Z boson and decaying into a pair of τ-leptons is presented. This search is based on proton-proton collision data collected at s=13 TeV by the ATLAS experiment at the LHC corresponding to an integrated luminosity of 140 fb−1. For the Higgs boson candidate, only final states with at least one τ-lepton decaying hadron

A lower eGFRcystatin C/eGFRcreatinine ratio is associated with greater cardiovascular risk (higher Framingham Risk Score) in Chinese patients with newly diagnosed type 2 diabetes mellitus

Background: Cardiovascular disease (CVD) is the leading cause of mortality in type 2 diabetes mellitus (T2DM) patients. Shrunken pore syndrome (SPS) is defined as eGFRcystatin C/eGFRcreatinine ratio 0.85, eGFRcystatin C/eGFRcreatinine≤0.85 increased FRS risk (OR = 1.95, 95%CI = 1.18–3.21, p < 0.01). After adjustment for confounding factors, increased eGFRcystatin C/eGFRcreatinine ratio was associa

The effect of workpiece grain size on surface integrity in orthogonal cutting of Inconel 718

Inconel 718 represents a large portion of high-temperature metals in key industries, where the machining-induced surface integrity is quite important. As the different grain size results in various densities of grain boundaries in the deformed area, the surface integrity can be significantly affected. This paper studies the effect of workpiece grain size on machining-induced surface integrity when

Leisure time physical activity in middle-aged and older adults aging with long-term spinal cord injury : Changes over six years

Background: Regular leisure time physical activity (LTPA) has beneficial health effects in people with spinal cord injury (SCI). Yet, participation in LTPA is low, and little is known about changes many years after injury. Objectives: To determine changes in LTPA in middle-aged and older adults with long-term SCI over six years, investigate associations with gender, age, injury characteristics and

Översvämning på jordbruksmark- Ett hot mot svensk livsmedelsförsörjning? En studie över planeringsstrategier i Eslövs kommun

As the climate changes the risks to agriculture increases which is a threat to food security around the world. One such risk is an increase in rainfall which can lead to decreased crop yields. Sweden today is dependent on other countries for their food supply, however the countries it depends on will suffer more from climate related risks to their agriculture meaning that Sweden's own food pro

Att bo tätt: En trend eller en socialt hållbar strategi? En studie av Lunds kommuns arbete med förtätning

Today, sustainable development permeates the whole of society, affecting how cities are planned and developed. Densification is a relatively new trend in urban planning to build new housing in growing cities while promoting sustainability. This study therefore examines urban densification in Lund, focusing on social sustainability within the context of municipal development. By utilizing method tr

Taktiker och strategier i den tillfälliga användningen av stadens mellanrum - En fallstudie över Institut for (x) användning av Godsbanearealerne i Aarhus

Denna studie tar avstamp i den tudelade akademiska debatten kring vilka potentialer och fallgropar det finns för tillfällig användning av stadens mellanrum, och har syftat till att undersöka hur Institut for (x) har lyckats upprätthålla sin tillfälliga användning av Godsbanearealerne i Aarhus över en längre tidsperiod. Genom intervjuer med representanter för Institut for (x) och Aarhus kommun, harAgainst the backdrop of a divided academic debate on the potentials and pitfalls for temporary use of urban space, this essay aims to explore how Institut for (x) as a temporary use project has been able to maintain their use of Godsbanearealerne in Aarhus over a longer period of time. This has been done through interviews with representatives of Institut for (x) and Aarhus municipality, where the

Neoliberal Styrning och PPP: En analys av Jägersroprojektet i Malmö

This thesis examines the ownership and governance of SMT Malmö Partner Holding AB in the context of the Jägersro urban development project in Malmö. It explores how a mix of public and private interests shapes urban projects through neoliberal governance, with a particular emphasis on Public-Private Partnerships (PPP). Through a comprehensive literature review, the paper establishes a theoretical

Effect of Short-Term Lactic Fermentation on Polyphenol Profile and Antioxidant Capacity in White and Red Quinoa Varieties

Quinoa (Chenopodium quinoa Willd.) is a pseudocereal originally grown in the Andean region of South America. This study focused on investigating the changes in phenolic profile and antioxidant capacity in white and red quinoa varieties after short-term fermentation with Lactiplantibacillus plantarum 299v®. During fermentation, pH and lactic acid formation were monitored every three hours until pH

Steroid transformation in aqueous two-phase systems: side-chain degradation of cholesterol by Mycobacterium sp.

We report on the use of aqueous two-phase systems for the side-chain degradation of cholesterol into androst-4-ene-3,17-dione (AD) and androsta-1,4-diene-3,17-dione (ADD) by Mycobacterium sp. A problem encountered at the start of this investigation, extensive aggregation of the cells, was solved by careful choice of the polymer and detergent composition of the phase system. The systems showing the

Perspective: multi-configurational methods in bio-inorganic chemistry

Transition metal ions play crucial roles in the structure and function of numerous proteins, contributing to essential biological processes such as catalysis, electron transfer, and oxygen binding. However, accurately modeling the electronic structure and properties of metalloproteins poses significant challenges due to the complex nature of their electronic configurations and strong correlation e

Pathways of ice multiplication in nimbostratus clouds during the Indian summer monsoon

The present study illustrates the microphysical parameters of nimbostratus clouds during the Indian summer monsoon using airborne and radar observations conducted as part of the Cloud Aerosol Interaction and Precipitation Enhancement Experiment (CAIPEEX), and simulations with the Weather Research and Forecasting (WRF) model. The study also analyzes the impact of secondary ice production (emphasizi

The sPHENIX Micromegas Outer Tracker

The sPHENIX Time Projection Chamber Outer Tracker (TPOT) is a Micromegas based detector. It is a part of the sPHENIX experiment that aims to facilitate the calibration of the Time Projection Chamber, in particular the correction of the time-averaged and beam-induced distortions of the electron drift. This paper describes the detector mission, setup, construction, installation, commissioning and pe

Studies of peptidolysis during early maturation and its influence on low-fat cheese quality

The effects of peptidolysis during early cheese ripening were studied in a low-fat (10% fat), round-eyed, semi-hard cheese using gel permeation chromatography and determinations of N content in cheese extracts. Addition of a heat-treated culture of Lactobacillus helveticus enhanced the peptidolytic activity even during the first weeks of cheese ripening. An aminopeptidase was found to have the nec