Adult neurogenesis in the mammalian brain, including in humans, occurs throughout life in distinct brain regions. Alterations in adult neurogenesis is a common phenomenon in several different neurodegenerative disorders, which is likely to contribute to the pathophysiology of these disorders. This review summarizes novel concepts related to the interplay between autophagy and microRNAs in control

A novel DCV-system controls the air-change rate for each apartment in multifamily buildings based on two indoor air parameters: 1) the moisture load (supply), and 2) volatile organic compounds. With a central fan, but decentralized control boxes placed outside each apartment, the system controls the air-change rate for each apartment. This paper’s main aim is to determine the potential of this DCV

The abrupt emergence of COVID-19, has ushered in health crises around the world and has affected global security. This pandemic shows that the relationship between security affairs and global health is becoming one of the more complicated topics in world politics. The states’ unilateral and individualized response to this transnational threat marks a shift in international relations away from glob

Ground improvement with lime-cement pillars is becoming increasingly common in the Nordic countries for exploitation of areas with poor stability. However, there is a need for non-destructive methods for volumetric quality control of the ground improvement. The quality control can be divided into two steps where the first include quality control at the installation process with monitoring of produ

We revisit and substantially extend the evidence on the importance of instruction time for student achievement on international assessments. We first successfully replicate the estimate of a positive effect of weekly instruction time in the seminal paper by Lavy (Economic Journal, 125, F397-F424) in a narrow sense. We then extend the analysis to data from other international student assessments an

I tider av ökad e-handel och externhandel kan en plats som vill attrahera besökare i gränslandet mellan turism och handel inte enbart förlita sig på mätbara kvaliteter som utbud och tillgänglighet. Det gäller istället att göra platsen lite roligare, intressantare, mer unik och rikare på upplevelser.

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The central challenge tackled in this thesis is the development of an optical imaging approach capable of multidimensional image capture of dynamic samples. Many conventional optical imaging approaches, which can obtain dimensional information such as spectral, polarisation, or volumetric, to name a few, about samples either employ sequential image capture or parallelised detector arrangements. Du

Vägledningen ingår i projektet "Sjyst data!", som syftar till att ta fram förutsättningar för en integritetsmärkning av digitala tjänster.

Overview: Drawing from ethnographic observations at senior camps, this paper discusses the contradiction between wanting to push participants into trying newactivities and needing to pull them back to ensure safety.Theme: Social and Cultural Perspectives on Aging

Background: To target specific neuronal populations by gene transfer is challenging. A complicating fact is that populations of neurons may have opposing roles despite being found adjacent to each other. One example is the medium spiny neurons of the striatum. These cells have different projection patterns, a trait used in this study to specifically target one population. New Method: Here we prese

We have performed quantum mechanics (QM), molecular mechanics (MM) and hybrid QM/MM calculations to study the stereospecific proton exchange of glutathiohydroxyacetone (HOC-SG) by glyoxalase I (GlxI). We did the QM/MM calculations with a large QM system (246 atoms) to investigate the proton-exchange mechanism. Moreover, single-point big-QM energies with 1303 atoms in the big QM system and 22,412 a

Polymer electrolyte fuel cells (PEFCs) have shown a great potential to be used in several applications, e.g., portable, mobile and stationary systems. Each of the mentioned applications demands from PEFCs different operating conditions to perform in the best possible manner. Knowing in detail the behavior of their internal components will help to improve the mechanical and thermal properties of th

The aim of this study was to evaluate the role of depth of anesthesia on POCD after major ENT surgery and to assess changes in postoperative inflammatory markers in patients undergoing major ENT surgery. Thirty two patients aged 40 to 94 yrs, scheduled for surgery under general anesthesia were randomly assigned to one of two groups. In group A (AEP group) depth of anesthesia (DOA) was measured wit

Introduction: Trauma stress and neuro-inflammation caused by surgery/anaesthesia releases cytokines. This study analysed impact of Auditory Evoked Potential Index (AAI) depth-of-anaesthesia titration on the early plasma IL-6 release after eye surgery under general anaesthesia. Method: This is a subgroup analysis of a prospective randomized study on the effect of auditory evoked potential guided an