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Progressive striatonigral degeneration in a transgenic mouse model of multiple system atrophy : translational implications for interventional therapies

Multiple system atrophy (MSA) is a rapidly progressive neurodegenerative disorder characterized by widespread oligodendroglial cytoplasmic inclusions of filamentous α-synuclein, and neuronal loss in autonomic centres, basal ganglia and cerebellar circuits. It has been suggested that primary oligodendroglial α-synucleinopathy may represent a trigger in the pathogenesis of MSA, but the mechanisms un

Game-theoretic network bandwidth distribution for self-adaptive cameras

Devices sharing a network compete for bandwidth, being able to transmit only a limited amount of data. This is for example the case with a network of cameras, that should record and transmit video streams to a monitor node for video surveillance. Adaptive cameras can reduce the quality of their video, thereby increasing the frame compression, to limit network congestion. In this paper, we exploit

Tjänstelogik i välfärden : En modell för samskapande mellan professionella med barnet i fokus

Denna bok handlar om hur välfärdsorganisationer kan samskapa värde tillsammans med den som de är till för. Boken belyser betydelsen av att förstå olika verksamheters perspektiv – socialtjänsten, barn- och ungdomspsykiatrin och skolan – genom yrkesgruppernas egna röster för att effektivt kunna ta tillvara varandras kompetenser. I boken föreslås en modell för samskapande i välfärdstjänster som bygge

Nature’s services at risk in a changing climate

Climate change is increasingly posing a threat to biodiversity, both through its direct effects on organisms and through indirect effects resulting from changes in land use. Preserving biodiversity is an ethical obligation, but it is also increasingly being realised that biodiversity contributes to ecosystem services, i.e. ecosystem processes important for human needs and prosperity. In order to a

Clitoral surgery on minors : an interview study with clinical experts of differences of sex development

OBJECTIVES: Clitoral surgery on minors diagnosed with differences of sex development is increasingly positioned as a violation of human rights. This qualitative study identified how health professionals (HPs) navigate the contentious issues as they offer care to affected families.DESIGN: Qualitative analysis of audio-recorded semistructured interviews with HPs. All of the interviews were transcrib

Att förstå varandra och tänka om

En modell för samskapande mellan professionella med barnet i fokusDenna bok handlar om hur välfärdsorganisationer kan samskapa värde tillsammans med den som de är till för. Boken belyser betydelsen av att förstå olika verksamheters perspektiv – socialtjänsten, barn- och ungdomspsykiatrin och skolan – genom yrkesgruppernas egna röster för att effektivt kunna ta tillvara varandras kompetenser. I bok

Climate models go green

The use of coal, oil and gas, and land use change, has caused emissions of carbon dioxide which equals to about 550 billion tons of carbon. Half of these have accumulated in the atmosphere, which warms our climate with profound effects on natural and human systems. The other half has been absorbed by the oceans and the biosphere. Climate change affects the strength of these ‘ carbon sinks’. Knowle

Can better sex education tackle the rise in female genital cosmetic surgery?

It has been suggested that “comprehensive sex education” is part of the solution for the rise in female genital cosmetic surgery (FGCS). This chapter represents the first attempt to outline what such sex education might entail. The strengths and weaknesses of sex education approaches are discussed. The inclusion of more accurate information relating to genital appearance and sexuality diversity an

Oral and infusion levodopa therapy in the management of Parkinson’s disease

Introduction: The clinical diagnosis of Parkinson’s disease (PD) is based on the identification of bradykinesia and at least one additional feature among rigidity, resting tremor and postural instability. These clinical features have been estimated to appear when at least 50% of the nigral dopamine neurons and 70% of putaminal dopamine tissue contents are lost [1]. Dopaminergic imaging suggests th

Emittance manipulation by first- and second-order lattice control

The lattice of the MAX-I electron storage ring has been investigated and tuned towards small momentum compaction values. By measurements of the synchrotron frequency, bunch length, horizontal beam size and beam movement, the beam has been found to behave in reasonable agreement with the predictions of the lattice model up to second order in energy deviation. Both longitudinal and horizontal emitta