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Background: Sodium-glucose cotransporter-2 inhibitors (SGLT2i) are increasingly used in patients with type 2 diabetes, chronic kidney disease, and heart failure. However, their safety and efficacy in patients with congenital or surgically altered urogenital anatomy remains underexplored. Methods: We conducted a narrative review of current evidence regarding the use of SGLT2i in patients with urina

Colorectal cancer (CRC) is linked to the WNT/β-catenin signaling as its primary driver. Aberrant activation of WNT/β-catenin signaling is closely correlated with increased incidence, malignancy, poorer prognosis, and even higher cancer-related death. Research over the years has postulated various experimental models that have facilitated an understanding of the complex mechanisms underlying WNT si

This paper addresses the critical gap in understanding the justice implications of renewable energy transitions, particularly concerning the agency of different actor groups, including marginalised and local communities. Given the urgency of transitioning to renewables to mitigate climate risks, it highlights the need for more human centric approaches to ensure equitable outcomes. In this context,

Management of drained forested peatlands has important implications for carbon budgets, but contrasting views exist on its effects on climate. This study utilised the dynamic ecosystem model ForSAFE-Peat to simulate biogeochemical dynamics over two complete forest rotations (1951–2088) in a nutrient-rich drained peatland afforested with Norway spruce (Picea abies) in southwestern Sweden. Model sim

Objective Half of all adult emergency department (ED) visits with a complaint of dyspnea involve acute heart failure (AHF), exacerbation of chronic obstructive pulmonary disease (eCOPD), or pneumonia, which are often misdiagnosed. We aimed to create an artificial intelligence (AI) diagnostic decision support tool to detect patients with AHF, eCOPD, and pneumonia among dyspneic adults at the beginn

‘Visibility’ is a concept often used in EU terminology as a means to advancing the EU’s reputation and standing in the world. Projections of EU visibility reveal changing conditions for international recognition where being seen is highly valued. This chapter examines the link between EU foreign policy, digitalization and public diplomacy, and especially the role of visibility in European Union (E

Ever since participation entered mainstream development discourse, critics have attacked it as form of political control. If development is indeed an 'anti-politics machine' (Ferguson, 1994), the claim is that participation provides a remarkably efficient means of greasing its wheels. But do participatory practices and discourse necessarily represent the de-politicisation of development? This pape

This article examines how more democratic forms of state-citizen engagement can be engineered under less than favorable political conditions, through the case of the Village Development Committees under the Left Front government in West Bengal, India. Our research shows that these Committees embodied empowered participatory governance ideals and made meaningful contributions to citizens' participa

This article examines the operation of Kudumbashree, the Poverty Eradication Mission for the Indian State of Kerala. Kudumbashree operates through female-only Neighbourhood Groups, which aim to contribute to their participants' economic uplift, and to integrate them with the activities and institutions of local governance. As such, Kudumbashree echoes poverty alleviation programmes elsewhere in th

This paper presents a relational approach to the study of poverty (. Mosse, 2010), and uses this to critically evaluate state strategies for identifying and alleviating poverty in Kerala, India. It traces these from national planning documents through to their point of implementation, drawing on qualitative research in two of Kerala's poorest Districts. Ideas of participatory poverty classificatio

This paper looks at the role of gender in the shaping and exercise of political authority. Its empirical focus is a slum in central Trivandrum, Kerala's capital city, which is undergoing a phased process of formalisation and rebuilding funded through a flagship Indian national programme, the JNNURM. The upgrade project should offer a dense network of ‘invited’ spaces for female participation withi

One of the benefits often claimed for 'moving' the state closer to people through the institutional reforms of democratic decentralisation is an improvement in the inclusion of politically marginalised groups. Decentralisation promises to deliver both the closer physical presence of centres of government and the formalisation of practices of representation at the grassroots. These changes in turn

This paper investigates governance reform which aims to 'move the state' closer to people, arguing that greater attention needs to be paid to two questions: how does political decentralisation affect the ways in which authority is exercised? And what spaces does it leave open for poor people's agency? It focuses on West Bengal, an Indian innovator of decentralisation through panchayati raj ('rule

This paper examines how India’s national urban development agenda is reshaping relationships between national, State and city-level governments. Jawaharlal Nehru National Urban Renewal Mission, the flagship programme that heralded a new era of urban investment in India, contained a range of key governance aspirations: linking the analysis of urban poverty to city-level planning, developing holisti

Expanded state-subsidised housing programmes in middle-income countries raise questions about the displacement and socio-spatial marginalisation of poor households. Examining these questions through people’s experiences of resettlement indicates the importance of mobility to their lives. Drawing on a mixed-method comparative study of Ahmedabad, Chennai and Johannesburg, we ask: How does the reloca

This paper looks at two governance challenges that sit behind global commitments to deliver ‘cities without slums’: under what conditions can participatory ideals be successfully transferred to housing redevelopment programmes, and under what conditions can participatory slum redevelopment trigger wider shifts towards inclusive urban governance? It does so by examining Indian national slum redevel

The growing emphasis on affordable housing and the sharp increase in its supply in Indian cities over the past two decades is characterised by two features that diminish the inclusive and integrative role of affordable urban housing. The first is the move toward constructing new housing stock rather than upgrading existing stock. Second, most of this new housing, increasingly in the form of multi-

This paper addresses an important, but under-studied, pathway for knowledge production in the field of urban planning: the practitioner engaging with academia through the writing of a PhD. Drawing on our own experiences of doctoral mentoring, in dialogue with PhD candidates, we reflect on the questions and challenges this form of knowledge production raises. The paper aims to extend planning theor

Large-scale inter-city infrastructure projects are proliferating across the Global South as industrial policy-makers have used spatial planning to purposefully transform regions’ economic and urban geographies. The Make in India policy and its promotion of industrial development corridors is emblematic of these trends, and this paper explores the relationship between this emergent national spatial