Det är sorgligt att Tro och solidaritet sänker sig till denna låga debattnivå av personangrepp istället för att framföra sakligt grundad kritik som skulle kunna föra debatten framåt. Ardins personligt upprörda tonfall blir för mig ytterligare ett bevis på att det är något som skaver och att det finns lik i garderoben. Jag upp­repar mitt förslag om en oberoende utredning av relationen mellan Tro oc

We present SVclone, a computational method for inferring the cancer cell fraction of structural variant (SV) breakpoints from whole-genome sequencing data. SVclone accurately determines the variant allele frequencies of both SV breakends, then simultaneously estimates the cancer cell fraction and SV copy number. We assess performance using in silico mixtures of real samples, at known proportions,

Lunds universitets yttrande över den s k arkivutredningen.

We measured a set of π±Σ∓, π0Σ0, and π−Σ0 invariant mass spectra below and above the K¯N mass threshold in K−-induced reactions on deuteron. The measured πΣ mass spectral shape is well reproduced via the two-step mechanism, i.e., a neutron knocked out at a forward angle from a deuteron by an incident K−, with the K¯ recoiled backward reacting with the residual nucleon to produce π and Σ. We deduce

The binding of uropathogenic Escherichia coli to the globo series of glycolipids via P pili is a critical step in the infectious process that is mediated by a human‐specific PapG adhesin. Three classes of PapG adhesins exist with different binding specificities to Galα4Gal‐containing glycolipids. The structural basis for PapG recognition of the human glycolipid receptor globoside was investigated

With reach far beyond the borders of one's own country, manipulative information influence can be used to threaten international security. Still, despite this threat, both researchers and practitioners are puzzled by how information influence is conducted. This study aims to contribute to this puzzle solving by, using China as empirical base, analyzing the procedure of one known case of infor

During the NATO application process for Sweden and Finland, Türkiye has halted the rapid pace of member states ratification through a set of conditions. This thesis’ aim is to examine the mechanisms behind the gatekeeping position upheld by Türkiye. My object of study consists of a transcript of a press briefing, held by the President of the European Parliament and the NATO Secretary General, and

Background: Pathological aggregation of tar DNA-binding protein 43 (TDP-43) in the brain is the primary cause of many cases of frontotemporal lobar degeneration (FTLD), amyotrophic lateral sclerosis (ALS) and limbic-predominant age-related TDP-43 encephalopathy (LATE). It is therefore imperative to establish empirical staging systems to characterize and distinguish stereotypical patterns and commo

At very high energies (VHE), the emission of γ rays is dominated by discrete sources. Due to the limited resolution and sensitivity of current-generation instruments, only a small fraction of the total Galactic population of VHE γ-ray sources has been detected significantly. The larger part of the population can be expected to contribute as a diffuse signal alongside emission originating from prop

A novel strategy for the purification of carbohydrate-based chemical libraries synthesized in solution was developed. Purification of reaction products was accomplished by means of solid-phase extraction enabled by protecting the 2-, 3-, 4-, and 6-hydroxyl groups of a galactose derivative as their hydrophobic O-laurates. The presence of multiple O-laurates allowed adsorption of reaction products o

Purified PapG adhesin from the genetically well-defined uropathogenic Escherichia coli strain J96, as well as whole bacteria, were bound to microtiter plates that carried covalently bound globotetraose and galabiose. The binding was inhibited by soluble saccharide derivatives corresponding to the globoseries of glycolipids, including all di-, tri-, tetra-, and pentasaccharide fragments of the Fors

Paperpresentation. Textbegreppets problematik, DuRietz textbegrepp.

Class actions in Sweden are not flourishing. This paper examines why the oldest class action regime in Scandinavia has not developed into anything more than a peripheral addition to the Swedish legal landscape, drawing on relevant procedural, political, and sociological insights. It is divided into two sections that (1) analyse the reform process in the 1990s and latest developments, including mai

The Cherenkov Telescope Array (CTA) will be the next generation very-high-energy gamma-ray observatory. CTA is expected to provide substantial improvement in accuracy and sensitivity with respect to existing instruments thanks to a tenfold increase in the number of telescopes and their state-of-the-art design. Detailed Monte Carlo simulations are used to further optimise the number of telescopes a