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While a bottom-up approach to identifying problems affecting food production among small-scale farmers has been urged as an appropriate means of finding sustainable solutions, few studies have determined the practical process of doing so and measured the outcomes of such an approach. This paper uses information gained mainly through focus groups with small-scale farmers and semi-structured intervi
With urban populations worldwide expected to witness substantial growth over the next decades, pressure on urban land and resources is projected to increase in response. For policy-makers to adequately meet the challenges brought about by changes in the dynamics of urban areas, it is important to clearly identify and communicate their causes. Floods in Douala (the most densely populated city in th
Inter-annual climatic variability over a large portion of sub-Saharan Africa is under the influence of the El Niño-Southern Oscillation (ENSO). Extreme variability in climate is a threat to rural livelihoods in sub-Saharan Africa, yet the role of ENSO in the balance between supply and demand of net primary productivity (NPP) over this region is unclear. Here, we analyze the impact of ENSO on this
This investigation takes its point of departure in the prominent use of the term ’musicality’ as a prestige word in theatre discourse where, obviously, not exactly the same reference and meaning is ascribed to the concept as in contexts of music. There seems to be very little previous research in this area, if any. The research question is formulated thus: What do theatre practicians mean when the
In every human being, there is a substantial proportion (1-2 kg) of total body weight constituted by the gut microbiota content in the gastro-intestinal system. Recent research findings, based on mapping of the microbiome, have stated that in healthy subjects, the gut microbiota richness and diversity is higher as compared to obese subjects or patients suffering from cardiometabolic disease, or ev
The large image volumes in breast tomosynthesis (BT) have led to large amounts of data and a heavy workload for breast radiologists. The number of slice images can be decreased by combining adjacent image planes (slabbing) but the decrease in depth resolution can considerably affect the detection of lesions. The aim of this work was to assess if thicker slabbing of the outer slice images (where le
Mucus covers the epithelium found in all intestinal tracts, where it serves as an important protecting barrier, and pharmaceutical drugs administrated by the oral, rectal, vaginal, ocular, or nasal route need to penetrate the mucus in order to reach their targets. Furthermore, the diffusion in mucus as well as the viscosity of mucus in the eyes, nose and throat can change depending on the relative
There are two main bioengineering approaches to extending the half-life of factor (F)VIII or FIX products used for hemophilia replacement therapy. These are fusion to Fc-immunoglobulin G (FVIII and FIX) or to albumin (FIX) or pegylation/glycopegylation (FVIII and FIX). Four FVIII and three FIX products are in clinical development or have recently been licensed in regions of the world. The reported
Background and purpose Increased interleukin 16 (IL-16) levels in carotid plaques have been associated with reduced incidence of cardiovascular (CV) events during follow-up in patients who underwent carotid endarterectomy (CEA). In the present study we aimed to determine whether high circulating levels of IL-16 also are associated with a decreased risk of CV events after CEA. Methods Patients, who
In Parkinson's disease (PD), pathological microstructural changes occur and such changes might be detected using diffusion magnetic resonance imaging (dMRI). However, it is unclear whether dMRI improves PD diagnosis or helps differentiating between phenotypes, such as postural instability gait difficulty (PIGD) and tremor dominant (TD) PD. We included105 patients with PD and 44 healthy controls (H
Background and purpose — Randomized trials have found that treating spinal burst fractures with reduction and posterior fixation is adequate without the use of bone grafting for definitive fusion. Restitution of intervertebral mobility of such an unfused segment after fracture healing may unload the adjacent parts of the spine and reduce the risk of degeneration of these segments. We used radioste
The aim was to compare postprandial plasma levels of calprotectin, cortisol, triglycerides and zonulin between a control breakfast and a moderately low-carbohydrate test breakfast, given randomly after 10-h fast. Blood samples were collected before and repeatedly after the meal. Plasma calprotectin, cortisol, triglycerides and zonulin were analyzed. The total area under the curve (tAUC) and change
The creation of an efficient public transport system requires collaborations between formal independent organizations. This paper examines collaborations between public and private organizations and passengers, with the aim of contributing to the conceptual understanding of collaborations on public transport. The study begins by describing previous research on collaboration in the public transport
