Mitochondria are the main organelles in eukaryotic cells involved in energy production together with their role in other mechanisms including intermediate metabolism, calcium signaling and apoptosis. Due to their importance in the correct function of the cell, genetic mitochondrial disorders can present a wide variability of symptoms, such as epilepsy, skeletal and cardiac myopathy and intellectua

På höghastighetslinjerna som planeras byggas i Sverige är det satt som mål att köra i 320 km/h. Att köra så pass mycket snabbare än det görs i dagsläget kräver ett kontaktledningssystem vars kontakttråd klarar av att vara stabilt och rakt uppspänt så att strömavtagaren kan gå jämt och inte orsaka att kontakttråden börjar svaja. Det resulterar i krav på att kontakttråden spänns upp med ett högre mo

This paper investigates empirical determinants of current account positions worldwide with a focus on the countries that started out as the European Monetary Union (including Greece that joined in 2001). Specifically, it addresses the question whether current accounts inside the Eurozone have reacted more sensitively to changes in macroeconomic fundamentals due to the facilitation of inter-country

Bakteriers kidnappning av mänskligt protein för att ta sig igenom vävnad För att sår och vävnadsskador ska läka behöver kroppen kunna bryta ner gammal vävnad för att göra plats åt nya celler, en process som även är viktig för barns bentillväxt. Detta komplexa system styrs av en typ av proteiner som är strikt reglerade men obalans i regleringen kan leda till cancer samt andra sjukdomar som hjärt-

During manufacturing of beverage packages, the pre-laminated hole get subjected to various mechanical loading. Thus needs a greater comprehension and knowledge of its behaviour to understand packaging materials. In this Master's thesis, the behaviour of the thin membranes consisting of polymer and aluminium foil has been studied when subjected to pressure. Mechanical, visual, as well as virtua

Sverige brukar få hög placering i internationella jämförelser av sjukvårdssystem. Det gäller inte minst patientnöjdhet och kvalitet, läkartäthet och hälsoutfall. Ändå har de senaste åren varit mycket vanligt med larmrapporter om kris på sjukhusen med påstådda överfulla vårdsalar och personal som lämnar sjukvården pga för hög arbetsbörda och ohållbar arbetsmiljö. Situationen har dragit igång debattData Envelopment Analysis (DEA) which compares different Decision Making Units (DMUs) has been used by some scholars to find the most efficient hospitals within Sweden or within Nordic countries. In Sweden, healthcare is decentralized and provided mostly by the 21 county councils. Even private providers have to sign contracts with the county councils in order to be permitted to operate within thei

Reglering och transport av S100A9 i cancer S100A9 är ett protein involverat i immunförsvaret och fungerar som en signal mellan olika celler för att optimera inflammation. Bortsett från det, har immunförsvaret som roll att bekämpa cancer. Där blir i stället effekten av S100A9-signalering att immunförsvarets attack dämpas och tumören gynnas. Det är därför av intresse att veta mer om detta signalsysS100A9 is a calcium binding protein commonly found in cancer, autoimmunity and inflammation. Factors in the tumor microenvironment can induce cancer cells to start expressing S100A9. This protein has also been found to be up regulated and have different subcellular distribution during hypoxia. In this study I used western blot to analyze the regulation of expression and intra-cellular transport of

This study investigates the effect of unemployment on health and rank-dependent indices of income-related health inequality in Europe during the period 2006-2015, using data from the Survey of Health, Ageing and Retirement in Europe. I use a recently proposed general method of decomposition and a panel data approach with individual fixed effects, and find a significant negative relationship betwee

The deep sea fish C. monstrosa (known as the rat fish) is a common bycatch of shrimp trawling. The rat fish carries on its back a vigorous venom spine. Some of the most toxic organisms on this planet are marine. The active substances differ in the venoms of the toxic organism, but the active substances are in many cases peptides. Natural peptides found in venoms have recently become more common ca

För att förutsäga beteendet hos mekaniska dynamiska system används beräknings-modeller som utgår ifrån systemens massa, styvhet och dämpningsegenskaper. Dessa modeller kan vara avancerade eller lätthanterliga mycket beroende på hur dämpnings-mekanismerna modelleras. Syftet med arbetet var att undersöka hur mer avancerade materialmodeller för beskrivning av dämpningen påverkar systemets dynamik.Damping is present in all dynamic systems. In one way or another energy is being dissipated in the system. To capture this aspect of reality in a computational model is a difficult task. A common simplification is to assume that the damping is of a linear viscous nature. This assumption provides an equation of motion (linear dynamics) which is easy to handle mathematically. However, the simplicity of

Bakterier har också skelett Bakteriers cytoskelett består av olika typer av proteiner, som ansvarar för bland annat bakteriers rigiditet och form samt är delaktiga i olika tillväxtprocesser. En grupp cytoskelettproteiner som är delaktiga i just tillväxtprocesser är intermediära filament (IF). Syftet med arbetet var att försöka identifiera nya IF i bakterien Streptomyces coelicolor, en viktig baktCoiled coil is a simple and versatile type of protein fold. Proteins with this kind of structure play roles in a numerous kind of cellular processes, e.g. DNA repair, nucleoid organization, and cytoskeletal functions. Cytoskeletal intermediate filament (IF) proteins are an example of proteins containing large coiled coil domains. The eukaryotic cytoskeletal proteins tubulin and actin have well-stu

The evidence pointing to a fundamental link between abundance in natural resources and unsustainable development processes in developing countries has caught attention lately, one aspect of this being the „resource curse‟. This paper aims to demonstrate the extent to which the resource abundance can explain the unsustainable economic development process of Kazakhstan. It aims to answer the overarc

The main aim of the present study was to study memory interference using a more ecological approach, where competing events can be separated by the environmental context. In order to increase the ecological validity of the study, context was manipulated through the presentation of video clips instead of commonly used static pictures. The second aim of the study was to assess if the contextual cues

Jonathan Swift’s Gulliver’s Travels and Terry Pratchett’s Discworld novels set in Ankh-Morpork are similar enough that both can be treated as belonging to the subgenre of comic fantasy. The narratives foreground the fantastic, written to entertain and amuse its readers but also contain societal criticism in the form of satire or parody. This paper compares the unnatural aspects of Gulliver’s Trave

This study examined the acculturation strategies of immigrant adolescents in Sweden and their relation to the mental health symptoms. The participants were 101 immigrant adolescents and 52 Swedish adolescents 15 to 19 years old. ‘Immigration paradox’ was examined comparing the mental health of first and second generation of immigrants and the native Swedes. Youth Self Report was used to assess men

After more than 50 years of internal armed conflict, the peace agreement between the Colombian Government and the Revolutionary Armed Forces of Colombia- People’s Army (FARC-EP) raises both hope and concern. There are several opportunities for people, derived from wealth and land redistribution. However, the environmental sustainability of the mechanisms to implement the agreements represent the b

Abstract Author: Maria Bjärlestam Title: ” The most important thing is that we dare to face this”- A qualitative study about the experiences and ways of workning for school counselors when it comes to mental illness among adolscents Supervisor: Lina Ponnert Assessor: Tove Harnett The main purpose of this study was to investigate what thoughts school counselors have about the reasons for mental

This thesis analyses the discourse of cultural heritage by taking the European Heritage Label (EHL) as a case study. The European Heritage Label is an organization established in 2011 by the European Union (EU) and created an application process for historical and cultural sites to be labelled as “European Heritage”. This thesis aims to critically analyse heritage as a concept that is used and pro

Aims/hypothesis The aims of this project was to investigate the effect of glucolipotoxic treatment on DNA methylation and gene expression patterns in pancreatic islets and functionally test if and how these changes alter insulin secretion. Methods Genome-wide mRNA expression and DNA methylation patterns were analyzed in human pancreatic islets after control or glucolipotoxic treatment. Alterations

Från ett nytt perspektiv Influencer marketing beskriver marknadsföringstekniken då företag använder inflytelserika och kända personer för att effektivt sprida ett budskap. Inom influencer marketing verkar de budskapspridande individerna, influencers, på de digitala plattformar som kallas sociala medier, däribland forum som Instagram, Facebook och Snapchat. Inom influencer marketing finns två parteFrom a new perspective Influencer Marketing describes a marketing technique where companies are using influential and well-known people to effectively spread a message. Through influencer marketing the message-spreading individuals, influencers, appear on the digital platforms known as social media, including forums such as Instagram, Facebook and Snapchat. Within influencer marketing there are tw