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Novel functions of cardiovascular P2 receptors

Popular Abstract in Swedish Sammanfattning Nukleotider påverkar kärltensionen och hjärtats slagkraft. Då ett blodkärl skadas, då blod koagulerar eller vid minskad syretillförsel till hjärtat frisätts en mängd ämnen från kärlväggar och blodceller. Bland annat frisätts så kallade nukleotider (ATP, ADP, UTP och UDP). Nukleotider har tidigare visats ha viktiga funktioner inuti cellen vid energiomsättnThe aim of the thesis was to examine the expression and function of the extracellular nucleotide P2 receptors in the cardiovascular system. In the cardiovascular system nucleotides are released during shear stress, hypoxia, ischemia, from endothelial cells, smooth muscle cells, aggregating platelets, inflammatory cells and erythrocytes. We demonstrate that ATP, ADP, UTP and UDP induce vascular rel

Performance of a multiband diversity antenna with hand effects

The implementation of multiband diversity antennas in compact mobile handsets, for the purpose of increasing transmission quality, is a topic of current interest in the mobile phone industry. In order to achieve the expected performance improvement in typical operating conditions, we not only have to contend with the challenges of designing multiple multiband antennas, which are closely spaced wit

Functional analysis of the mouse J chain

We have in this study analyzed the function of the murine Joining chain (J chain) in vivo. J chain is a polypeptide found in sera and secretions in complex with pentameric IgM and dimeric IgA. J chain is expressed in terminally differentiated B lymphocytes and needed for the transport of dimeric IgA and pentameric IgM over mucosal surfaces via the poly Ig receptor. A mouse deficient for J chain wa

Acute postoperative and cancer-related pain management, Patients´ experiences and perceptions in relation to health-related quality of life and the multidimensionality of pain

Popular Abstract in Swedish Vård och behandling av akut postoperativ och cancer-relaterad smärta: Patienters erfarenheter och uppfattningar i förhållande till hälsorelaterad livskvalitet och smärtans dimensioner Trots att det finns effektiva behandlingsmetoder för patienter med postoperativ smärta och cancer-relaterad smärta så lider många patienter av smärta. Denna avhandling beskriver patienterThis thesis describes patients in acute postoperative pain as well as patients with acute cancer-related pain in palliative care, and their experiences and perceptions of pain management in relation to HRQOL and the multidimensionality of pain. A combination of qualitative and quantitative methods was chosen. Data were collected using interviews and questionnaires; APS, SF:36 and a new developed q

Comprehensive Gamma-Ray Spectroscopy of 62Zn and Studies of Nilsson Parameters in the Mass A = 60 Region

Popular Abstract in English All ordinary matter around us is made out of atoms. In turn, the building blocks of the atoms are nowadays known to be three types of particles:electrons, protons and neutrons. The latter are called nucleons, as they together form the positively charged nucleus of the atom, around which the electrons are moving. The radius of the nucleus is about three orders of magnituComprehensive experimental knowledge of the 62Zn nucleus has been obtained from the combined statistics of four different experiments. The Gammasphere Ge-detector array in conjunction with the 4pi charged-particle detector array Microball was used to detect the gamma-rays in coincidence with evaporated light charged particles. In total twenty seven band structures have been observed in 62Zn, twent

Modelling of molybdopterin-dependent enzymes

Popular Abstract in Swedish Molybden ingår som en viktig del i två typer av biologiska system - dels i nitrogenas, som fixerar kvävgas ur atmosfären, och dels i de enkärniga molybdenenzymerna. De senare är enzymer som innehåller endast en molybdenatom i sina aktiva säten. De enkärniga molybdenenzymerna finns i en mängd levande system, från bakterier till växter och djur och även i människan. EnzymThe thesis deals with models for molybdopterin-dependent enzymes. Several model systems containing molybdenum or tungsten have been prepared and characterised, and their reactivity with oxygen atom acceptors and donors have been investigated. Oxygen atom transfer reactions involving oxomolybdenum bis-dithiolene complexes have been modelled using density functional calculations. The first molybden

A Braided View of a Knotty Story

Periodic orbits of 3-d dynamical systems admitting a Poincaré section can be described as braids. This characterisation can be transported to the Poincaré section and Poincaré map, resulting in the braid type. Information from braid types allows to estimate bounds for the topological entropy of the map while revealing detailed orbit information from the original system, such as the orbits tha

Cardiovascular and respiratory effects of apnea in humans

Popular Abstract in Swedish Dykresponsen Andningsuppehåll (apné) eller fridykning ställer stora krav på att så effektivt som möjligt disponera de förråd med syrgas som finns i kroppen. Känsliga organ såsom hjärnan och hjärtat kan inte klara sig utan syrgas någon längre tid. Huden, musklerna och magtarm-kanalen har däremot en större tolerans mot syrgasbrist. Kroppens syrgasförråd finns framför allThis thesis deals with cardiovascular and respiratory effects of apneas in humans. During apnea (breath-holding), a number of interacting cardiovascular reflexes are initiated, and together these reflexes are called the “diving response”. The main cardiovascular characteristics of the human diving response are reduced heart rate, decreased cardiac output, peripheral vasoconstriction, and increased

Klimatsäkrat Skåne

Klimatet förändras, och det är människans aktiviteter som är orsaken. Utsläpp av växthusgaser från fossila bränslen och ohållbar markanvändning på global, regional och lokal nivå driver den pågående uppvärmningen. Hur dessa drivkrafter utvecklas framöver avgör hur stora klimatförändringarna blir på sikt. Därmed återfinns klimatproblematikens orsaker, men även dess lösningar, i hur vi bygger och ut

Double directional radio propagation measurements and radio channel modelling pertinent to mobile MIMO communications in microcells

For simulating mobile MIMO performance, local area SNR variations can be reproduced if small-scale fading distributions are known, transmit bandwidths can be chosen appropriately if flat fading bandwidths are known, and, assuming plane waves, spatial covariance functions can be estimated if power-weighted histograms for angles of arrival (AOA) and angles of departure (AOD) are known. This paper re

Fe II fluorescence in symbiotic stars

Fe 0 fluorescence by PAR has been investigated in eight symbiotic starshaving a wide range in temperature of the hot component and orbitalperiod. The data used are spectra obtained from the IUE archive. Allpumping lines investigated in this work are in the short wavelengthregion of IUE (1200-2000 Å), except for He 0 λ 1084.942 andO 0 λ 1032.041. The resulting Fe 0 fluorescence lines are mainlyin t