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Exhaled aerosols and saliva droplets measured in time and 3D space: Quantification of pathogens flow rate applied to SARS-CoV-2

SARS-CoV-2 and its ever-emerging variants are spread from host-to-host via expelled respiratory aerosols and saliva droplets. Knowing the number of virions which are exhaled by a person requires precise measurements of the size, count, velocity and trajectory of the virus-laden particles that are ejected directly from the mouth. These measurements are achieved in 3D, at 15,000 images/s, and are ap

Multicenter trans-Atlantic experience with fenestrated-branched endovascular aortic repair of chronic post-dissection thoracoabdominal aortic aneurysms

Objective: This multicenter international study aimed to describe outcomes of fenestrated-branched endovascular aortic repairs (FB-EVAR) in a cohort of patients treated for chronic post-dissection thoracoabdominal aortic aneurysms (PD-TAAAs). Methods: We reviewed the clinical data of all consecutive patients treated by FB-EVAR for repair of extent I to III PD-TAAAs in 16 centers from the United St

Ers international congress 2022 : Highlights from the airway diseases assembly

The European Respiratory Society (ERS) celebrated the return of an in-person meeting in Barcelona, Spain, after 2 years of virtual congresses. The ERS Congress 2022 programme was replete with symposia, skills workshops and abstract presentations from all 14 assemblies, encompassing over 3000 abstracts presented in the form of thematic poster discussion and oral presentations. In this article, high

High-speed scattered-light imaging for sizing respiratory droplets

The COVID-19 pandemic has illuminated the lack of knowledge regarding the airborne transmission pathway of disease. The pathway consists of pathogens contained in small particles ejected when speaking and coughing. A crucial characteristic of these particles is their size that is connected to the their suspension longevity in the air as well as the location of generation and deposition within a su

Entanglement and thermokinetic uncertainty relations in coherent mesoscopic transport

A deeper understanding of the differences between quantum and classical dynamics promises great potential for emerging technologies. Nevertheless, some aspects remain poorly understood, particularly concerning the role of quantum coherence in open quantum systems. On the one hand, coherence leads to entanglement and even nonlocality. On the other, it may lead to a suppression of fluctuations, caus

Vad hände med de sociala relationerna under coronapandemin?

Under covid-19-pandemin blev många anställda rekommenderade eller tvingade att arbeta på distans (Fackförbundet ST, 2020; Wang m.fl., 2021). Sammantaget arbetade 30–40 procent av arbetstagarna hela eller delar av sin arbetstid på distans under pandemin (Myndigheten för arbetsmiljökunskap, 2021). Den fysiska arbetsplatsen var inte längre en självklarhet; från en dag till en annan blev i stället dis

Moraliska gränsdragningar i arbetet som spelutvecklare

Dataspelsbranschen beskrivs som både en kulturell näring och som en del av tech-industrin. De olika beskrivningarna ger skilda associationer och illustrerar branschens många sidor. Det är också illustrativt för arbetet som spelutvecklare, vilket ofta beskrivs som en skärningspunkt mellan såväl konstnärligt arbete och teknik, som mellan kultur och kommers. I ett pågående forskningsprojekt om spelut

Drug prescriptions preceding opioid-related deaths – a register study in forensic autopsy patients

Background/AimOpioid overdose deaths have increased in Sweden and other developed countries in recent decades, despite increased treatment efforts and harm-reduction interventions. Further knowledge in this field is needed if this trend is to be reversed. Previous research suggests that mental health and patterns of prescription of opioids and other prescription drugs are associated with increased

Non-negative matrix factorization for the analysis of complex gene expression data : Identification of clinically relevant tumor subtypes

Non-negative matrix factorization (NMF) is a relatively new approach to analyze gene expression data that models data by additive combinations of non-negative basis vectors (metagenes). The non-negativity constraint makes sense biologically as genes may either be expressed or not, but never show negative expression. We applied NMF to five different microarray data sets. We estimated the appropriat

Role of serotype and virulence determinants of Streptococcus pyogenes biofilm bacteria in internalization and persistence in epithelial cells in vitro.

Streptococcus pyogenes causes a multitude of local and systemic infections, the most common being pharyngitis in children. Recurrent pharyngeal infections are common and are thought to be due to the re-emergence of intracellular GAS upon completion of antibiotic treatment. The role of colonizing biofilm bacteria in this process is not fully clear. Here, live respiratory epithelial cells were inoc

Between Growth and Sustainability : Exploring the Construction of Sustainable Mobility in Swedish Transport Policy

Samtidigt som bilen är själva grunden för det sätt vi förflyttar oss i samhället, utgör bilismen den främsta orsaken till transportsektorns negativa miljö- och hälsoeffekter. Denna avhandling handlar om politiska försök att gå bortom bilen, mot en mer hållbar form av mobilitet. Hållbar mobilitet eller hållbara transporter, som är den mer använda termen i Sverige, har de senaste decennierna kommit Transport policies in Western Europe are increasingly framed in terms of sustainable mobility. This is a response to an urgent need to tackle adverse consequences of the transport system and implies changes in discourses related to transport. Exploring sustainable mobility is a fruitful way of studying discursive development in a policy field historically connected to priorities radically differen

Alveolar epithelial cells are competent producers of interstitial extracellular matrix with disease relevant plasticity in a human in vitro 3D model

Alveolar epithelial cells (AEC) have been implicated in pathological remodelling. We examined the capacity of AEC to produce extracellular matrix (ECM) and thereby directly contribute towards remodelling in chronic lung diseases. Cryopreserved type 2 AEC (AEC2) from healthy lungs and chronic obstructive pulmonary disease (COPD) afflicted lungs were cultured in decellularized healthy human lung sli