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Pharmacoeconomics and clinical practice guidelines : A survey of attitudes in Swedish formulary committees

Background: Swedish formulary committees are expected to influence prescribing practice by establishing and issuing drug lists and clinical practice guidelines, particularly now that financial responsibility for prescription drugs has been transferred from the national to the county council level. Objective: The purpose of this exploratory study was to identify the information sources and decision

Comparison of small-angle neutron and X-ray scattering for studying cortical bone nanostructure

In this study, we present a combined small-angle neutron and X-ray scattering (SANS and SAXS) study of the nanoscale structure of cortical bone specimens from three different species. The variation of the scattering cross section of elements across the periodic table is very different for neutrons and X-rays. For X-rays, it is proportional to the electron density while for neutrons it varies irreg

Dynamics of proteins in solution

The dynamics of proteins in solution includes a variety of processes, such as backbone and side-chain fluctuations, interdomain motions, as well as global rotational and translational (i.e. center of mass) diffusion. Since protein dynamics is related to protein function and essential transport processes, a detailed mechanistic understanding and monitoring of protein dynamics in solution is highly

Reflections on Naomi Klein's Pandemic Shock Doctrine

Drawing on and expanding Klein’s argument, this essay seeks to expose the all-to-human consequences of the emergence and expansion of digital capitalism. It begins with a summary of Naomi Klein’s article, emphasising the main arguments. Next, I discuss Klein’s essay in relation to Shoshana Zuboff’s work on surveillance capitalism to show how they are both essentially criticizing a biopolitical tur

Precision Improvements for Ray/Sphere Intersection

The traditional quadratic formula is often presented as the way to compute the intersection of a ray with a sphere. While mathematically correct, this factorization can be numerically unstable when using floating-point arithmetic. We give two little-known reformulations and show how each can improve precision.

The 1988 Massacres Still Haunt the Islamic Regime in Iran

In the summer of 1988, during the premiership of Mir-Hussein Mousavi, thousands of opponents of the Islamic Republic were extrajudicially executed while in prison. Newly published evidence from Amnesty International shows that Mousavi, despite his denials, was aware of the executions, casting a dark shadow over the reformist movement in Iran.

Speed and concentration of the covering time for structured coupon collectors

Let V be an n-set, and let X be a random variable taking values in the power-set of V . Suppose we are given a sequence of random coupons X1 , X2 , ..., where the Xi are independent random variables with distribution given by X. The covering time T is the smallest integer t ≥ 0 such that the union of the first t Xi's equal V . The distribution of T is important in many applications in combinatoria

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Overview of what is happening in the field of Dutch tax and charities at the moment.

Sleep in relation to psychiatric symptoms and perceived stress in Swedish adolescents aged 15 to 19 years

Background:Sleep affects psychiatric health and perceived stress during adolescence.Objective:The first aim of this study was to investigate the prevalence of poor sleep in a sample of Swedish adolescents aged 15 to 19 years. The second aim was to investigate correlations between: a) sleep and psychiatric symptoms and; b) sleep and perceived stress. The third aim was to examine possible sex differ