Treatment of neuroendocrine tumors with 177Lu-octreotate results in prolonged survival and improved quality of life for the patient. However, the treatment is today limited by side effects on kidney and bone marrow, and complete tumor remission is rarely seen. A possible way to minimize dose-limiting toxicity and to optimize this treatment method is to use radioprotectors in conjunction with radio

Grancalcin is a newly discovered cytosolic calcium-binding protein, belonging to the group of EF-hand proteins. Grancalcin is specifically associated with cells originating in the bone marrow. Grancalcin binds reversibly to secretory vesicles and plasma membranes in human neutrophils and might therefore play a role in the regulation of vesicle/granule exocytosis. We describe here the production of

hCAP-18 is a newly described protein of human neutrophilic granulocytes which belongs to the cathelicidin family of antimicrobial proteins. Members of this protein family share a common N-terminal sequence followed by a highly diverse antimicrobial, cationic C-terminus. The present work describes the production of recombinant hCAP-18, the generation of antibodies to the protein and the development

Vi vill med den här artikeln peka på att Sveriges städer har flera utmaningar kring styrning och hantering av vatten, samt föreslår sju principer för lösningar. Klimatförändringarna och den urbana tillväxten gör att åtgärder behövs nu för att hantera både vattenbrist och översvämning på ett integrerat sätt. Här fokuserar vi på kommunnivå och urbana områden, där vi argumenterar för att det behövs eWe argue in this paper that Swedish urban areas have several urgent challenges when it comes to water governance and we propose seven principles for addressing them. Climate change and urban growth call for swift action to manage both water scarcity and flooding in an integrated way. This paper focuses on the municipal level for which we argue that there is a need for a more systematic approach. T

Background: During 2013 and 2016 the region of Skåne, Sweden started to analyse human papillomavirus (HPV) and cytology in postmenopausal women 60–65 years of age. Our aim was to evaluate high-risk (HR) HPV mRNA testing for the triage of HPV DNA-positive postmenopausal women with normal cytology. Methods: A total of 271 women, 60–65 years of age, underwent liquid-based cytology (LBC) and HPV testi

Cell physiology and cellular responses to external stimuli are partly controlled through protein binding, localization, and expression level. Thus, quantification of these processes is pivotal in understanding cellular biology and disease pathophysiology. However, it can be methodologically challenging. Immunofluorescence is a powerful technique, yet quantification by this method can be hampered b

In this paper, pure paraffin was mixed with CuO (high thermal conductivity) and Span-80 (as a dispersant). The CuO/paraffin nanocomposite phase-change materials (PCMs) were synthesized with mass fractions of 0.3%, 0.6%, and 1.2%, by a two-step method. Heat-transfer characteristics of the heat-pipe-PCMs module and effects of fan power and heating power on the performance of the cooling module in a

Background: This study is designed to provide detailed knowledge on cognitive impairment after out-of-hospital cardiac arrest (OHCA) and its relation to associated factors, and to validate the neurocognitive screening of the Targeted Hypothermia versus Targeted Normothermia after Out-of-Hospital Cardiac Arrest trial (TTM2-trial), assessing effectiveness of targeted temperature management after OHC

Here we present a method to control the size of the openings in hexagonally organized BCP thin films of poly(styrene)-block-poly(4-vinylpyridine) (PS-b-P4VP) by using surface reconstruction. The surface reconstruction is based on selective swelling of the P4VP block in ethanol, and its extraction to the surface of the film, resulting in pores upon drying. We found that the BCP pore diameter increa

Purpose: Prolonged weightlessness exposure generates cardiovascular deconditioning, with potential implications on ECG circadian rhythms. Head-down (− 6°) tilt (HDT) bed rest is a ground-based analogue model for simulating the effects of reduced motor activity and fluids redistribution occurring during spaceflight. Our aim was to evaluate the impact of 60-day HDT on the circadianity of RR and vent

Cellular composition and morphology of components of photoreceptor apparatus of the retinae of camera eyes of some species of terrestrial gastropod pulmonate molluscs were studied and its evolutionary transformations were traced. It was demonstrated that all examined characteristics of photoreceptor apparatus of the most investigated species were normal for terrestrial pulmonates, while those of o

Den svenska coronastrategin är omstridd, också utanför landets gränser. Vem som har rätt lär framtiden utvisa, men Sverige särskiljer sig också genom sitt självklara avfärdande av en lockdown som ett otillbörligt ingrepp i den individuella friheten. Det är en svårbegriplig ståndpunkt, skriver Benny Carlson.Den svenska coronastrategin är omstridd, också utanför landets gränser. Vem som har rätt lär framtiden utvisa, men Sverige särskiljer sig också genom sitt självklara avfärdande av en lockdown som ett otillbörligt ingrepp i den individuella friheten. Det är en svårbegriplig ståndpunkt, skriver Benny Carlson.

This report represents the main findings from the first round of village-level community assessment of the economic and social impacts monitoring of COVID-19 in Myanmar. A total of 224 individuals (four per village, selected for their knowledge of the situation of the village, and representativity of key sub-groups), were interviewed across 56 villages, in two townships in every state and region a

Culturally oriented consumer research has predominantly been framed by two ideal types of reflexivity, which we characterize as existential and critical reflexiv-ity. Drawing from our research on divorced women who have been displaced from their domestically oriented, middle-class lifestyles, we develop an alternative con-ceptualization-reactive reflexivity-that highlights a different relationship

En presentation av vad landshövdingarna skrev om Östra Vingåker åren 1866-1900

Finns det något annat politikområde än narkotikapolitiken där en uttalad försämring tas till intäkt för att politiken har varit verkningsfull? Den frågan ställer debattörer i en slutreplik.

Kort beskrivning av hur brevväxling används som pedagogisk metod inom utbildningen på avancerad nivå i Litterär gestaltning ("Författarskolan"), LU.

Purpose: This paper seeks to overcome the mismatch between evaluation reports and the expectations of the target audience, by identifying crisis management professionals' expectations. Design/methodology/approach: An adapted stakeholder information analysis was used to survey the expectations of 84 crisis management professionals in the Netherlands. A general inductive analysis was applied to qual