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Global Proteome Survey -Transforming antibody-based affinity proteomics into a global discovery platform

Popular Abstract in Swedish En av de stora vetenskapliga bedrifterna hittills under 2000-talet är onekligen att man efter många års arbete för första gången lyckades kartlägga (sekvensera) samtliga mänskliga gener. Det mänskliga DNA:t är lokaliserat till cellkärnan och i princip så kan man likna en cellkärna med ett kontrollrum fyllt av manualer (DNA) som talar om cellens sammansättning och hur deProteomics is expected to generate new insights into biological processes as well as identify novel biomarkers and therapeutic targets since most biological functions are transmitted through proteins. However, due to the complexity displayed by a proteome and inherent limitations associated with current methodologies, proteomic analyses often result in incomplete coverage and inconsistent measurem

Influence of pressure drop in PEM fuel cell stack on the heat and mass balances in 100 KW systems

Proton Exchange Membrane (PEM) fuel cell systems have been studied as the alternatives of the internal combustion engine systems. However, these systems are not appearing in daily life yet, due to the high cost, shortage of infrastructure, technical issues, etc. Concerning technical issues, water/thermal management is a critical one to keep high proton conductivity in the electrolyte membrane for

A Quest for Legitimacy : Debating UN Security Council Rules on Terrorism and Non-proliferation

Popular Abstract in Swedish Efter terroristattackerna den 11 september 2001 har FN:s säkerhetsråd - med USA i spetsen - radikalt utvidgat sina egna befogenheter när det gäller att upprätthålla internationell fred och säkerhet genom att anta resolutioner som i praktiken är lagstiftande. Resolution 1373 (som behandlar terrorism) och resolution 1540 (som behandlar spridning av massförstörelsevapen tiSince the end of the Cold War, international politics and international law have not only become increasingly intertwined, but their mutual implications have also become increasingly recognized by scholars. Yet research explicitly addressing the question of how political factors affect the emergence of legal rules is still limited. This doctoral dissertation aims to take a step in the direction of

Conceptions, Categories, and Embodiment: Why Metaphors are of Fundamental Importance for Understanding Norms

The propositions in this chapter are to a large extent drawn from the thesis Metaphors and norms – understanding copyright law in a digital society (Larsson 2011b), however with some important complements, not least concerning the implications of categorisation. The chapter is explorative in bringing findings from cognitive linguistics into the quite common socio-legal task of studying norms. Its

Electropermeabilization in Experimental Tumour Treatment: Dosimetry and Tissue Effects

Short, electric high-voltage pulses can be used to transiently increase the permeability of cell membranes without significant loss of cell viability. During this period of time, extracellular and normally non-permeant, molecules are accessed the cytoplasm and the cell nucleus. This technique is called electroporation or electropermeabilization (EP). EP has been employed in vivo to internalise ant

In vivo and in vitro evolution of molecular mechanisms - Importance in B cell development and phage display

Bone marrow resident hematopoietic stem cells differentiate into all different types of lymphoid populations, there among mature naive B cells expressing IgM and IgD. During the maturation, the B cells are subjected to several steps of selection to ensure proper development of the antigen receptor. The mechanisms regulating the selection are to great extent unknown. In paper I of this thesis, we d

Lena Cronqvist: Reflections of Girls

Popular Abstract in Swedish Utgångspunkten för den här avhandlingen har varit det stora antalet bilder som motsäger den vanliga trenden i konst att avbilda flickor som oskyldiga, romantiska och sexualiserade. Målet med avhandlingen är att för första gången presentera forskning om den svenska konstnären Lena Cronqvists (född 1938) flickbilder och att skapa kunskap om bilder av flickor i konst i allThe starting point for this PhD, is the large number of girls that opposed the common trend in which girls are represented as innocent, romantic and sexual. The aim of this study has been to provide the first piece of research ever on this body of work by the Swedish artist Lena Cronqvist (b. 1938) and to cast new light on representations of girls in art in general. Cronqvist is one of Sweden's ma