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Bond-Test of Concrete and Overlays

Presented at the Int. Conference "Non-Destructive Testing in Civil Engineering", The British Inst. of Non-Destructive Testing, Liverpool, England, 1993

Influence of Plastic Dissipation on Apparent Fracture Energy Determined by a Three-Point Beding Test

A three-point bending test used for determining the fracture energy in modus I for wood perpendicular to the grain is studied, If the height of the specimen is varied, the results show a size effect, The specimens used in testing have been analyzed by finite element calculations with an anisotropic elasto-plastic material model in order to determine the influence of plastic dissipation. Analysis h

Asymptotics of Maximum Likelihood Parameter Estimates For Gaussian Processes: The Ornstein–Uhlenbeck Prior

This article studies the maximum likelihood estimates of magnitude and scale parameters for a Gaussian process of Ornstein-Uhlenbeck type used to model a deterministic function that does not have to be a realisation of an Ornstein- Uhlenbeck process. Specifically, we derive explicit expressions for the limiting values of the maximum likelihood estimates as the number of observations increases. The

Real-time detection of mAb aggregates in an integrated downstream process

The implementation of continuous processing in the biopharmaceutical industry is hindered by the scarcity of process analytical technologies (PAT). To monitor and control a continuous process, PAT tools will be crucial to measure real-time product quality attributes such as protein aggregation. Miniaturizing these analytical techniques can increase measurement speed and enable faster decision-maki

Drug repositioning in chemoprevention of colorectal cancer

BackgroundColorectal cancer (CRC) ranks as the third most frequently occurring cancer and the second leading cause of cancer-related deaths worldwide. In response to the high demand for an effective prevention strategy, chemoprevention, using medications to block the pathogenetic pathways of disease, might be an attractive strategy to offer a more effective option at a low cost. Therefore, we aime

Generation of aerosols by noninvasive respiratory support modalities : a systematic review and meta-analysis

Importance: Infection control guidelines have historically classified high-flow nasal oxygen and noninvasive ventilation as aerosol-generating procedures that require specialized infection prevention and control measures. Objective: To evaluate the current evidence that high-flow nasal oxygen and noninvasive ventilation are associated with pathogen-laden aerosols and aerosol generation. Data Sourc

A search for an unexpected asymmetry in the production of e+μ− and e−μ+ pairs in proton–proton collisions recorded by the ATLAS detector at s=13 TeV

This search, a type not previously performed at ATLAS, uses a comparison of the production cross sections for e+μ− and e−μ+ pairs to constrain physics processes beyond the Standard Model. It uses 139fb−1 of proton–proton collision data recorded at s=13 TeV at the LHC. Targeting sources of new physics which prefer final states containing e+μ− to e−μ+, the search contains two broad signal regions wh

Cytoreductive surgery with or without hyperthermic intraperitoneal chemotherapy in patients with advanced ovarian cancer (OVHIPEC-1) : final survival analysis of a randomised, controlled, phase 3 trial

BACKGROUND: The OVHIPEC-1 trial previously showed that the addition of hyperthermic intraperitoneal chemotherapy (HIPEC) to interval cytoreductive surgery resulted in improved progression-free and overall survival compared with cytoreductive surgery alone at 4·7 years of follow-up in patients with stage III epithelial ovarian cancer who were ineligible for primary cytoreduction. We report the fina