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PURPOSE: To establish neuronal connections in the rod and cone pathway between laminated rabbit retinal transplants and the host retina.METHODS: Fourteen adult rabbits received a complete full-thickness embryonic transplant. After survival times of 3 to 10 months, the retinas were studied under light microscope and with immunohistochemistry. Antibodies against protein kinase C (PKC), parvalbumin,
PURPOSE: To examine immunohistochemical markers in straight, well-laminated retinal transplants with special attention paid to the interphotoreceptor matrix, the Müller cells and the ganglion cells as these three retinal components have been abnormal in transplants produced by previous methods.METHODS: Nine rabbits underwent subretinal transplantation of a complete full-thickness embryonic neurore
PURPOSE: To establish the light and electron microscopic morphology of long-term full-thickness embryonic rabbit retinal transplants, with special attention paid to graft- host integration.METHODS: Eighteen rabbits received a complete embryonic neuroretina 19 days after conception. The transplants were positioned under the host retina, flat against the host retinal pigment epithelium with proper p
Adult and embryonic rabbit retinal sheets were transplanted into the subretinal space of adult rabbits. The transplants were either full-thickness with intact layering, or gelatin embedded and vibratome sectioned with the inner retina removed. The full-thickness grafts were positioned subretinally by means of a glass capillary in which they were partially folded. The vibratome sectioned ones were
PURPOSE: To develop an improved surgical technique making full-thickness retinal transplant possible, thereby achieving a normal laminated transplant with minimal rosette formation.METHODS: A total of 23 rabbits underwent vitrectomy, retinotomy, and subsequent subretinal transplant of a complete embryonic neuroretina using a specially crafted glass cannula. Of the 23 animals, 15 received a prenata
This study delineates the permissible scope for compulsory mental health interventions under the Convention on the Rights of Persons with Disabilities (CRPD). It was initially triggered by two competing positions within the current debate over the future of coercive psychiatry; a practice that is still omnipresent among states worldwide. According to one position, defended by the CRPD Committee amThis study delineates the permissible scope for compulsory mental health interventions under the Convention on the Rights of Persons with Disabilities (CRPD). It was initially triggered by two competing positions within the current debate over the future of coercive psychiatry; a practice that is still omnipresent among states worldwide. According to one position, defended by the CRPD Committee am
This thesis delves into two ‘edge areas’ located in and around East Jerusalem. It attempts to unfold and analyze the dynamics in these edge areas, while investigating the agency of the people present there through their own perceptions and practices towards the land, the urbanization processes, the power circulation and the structural impositions. Squeezed by a settler-colonial domination that con
Families living with mental illness express needs of support and experiences of burden that may affect their own health detrimentally and hence also their ability to support the patient. Mindfulness-based interventions have shown beneficial health effects in both clinical and healthy populations. The aim of the current study was to explore the effectiveness and usability of a web-based mindfulness
Here we report new reconstructions of winter temperature and summer moisture during the past millennium in southeastern Sweden, based on stable-isotope data from a composite tree-ring sequence, that further enhances our knowledge and understanding of seasonal climate variability in the Northern Hemisphere over the past millennium. Key features of these new climate proxy records include evidence fo
To explain reciprocity, direct or indirect, several proximate mechanisms have been proposed, yet little attention has been given to the specific underlying cognitive mechanisms. Regardless of what proximate rules underlie reciprocity, some kind of memory would be paramount. Corvids in general, and ravens, Corvus corax, specifically, have been shown to possess an array of sophisticated cognitive me
