Urbanisation is increasing worldwide, and there is now ample evidence of phenotypic changes in wild organisms in response to this novel environment. Yet, the genetic changes and genomic architecture underlying these adaptations are poorly understood. Here, we genotype 192 great tits (Parus major) from nine European cities, each paired with an adjacent rural site, to address this major knowledge ga

Complex diseases represent a number of common disorders such as allergic conditions, cardiovascular, metabolic and chronic inflammatory diseases. These diseases are caused by a combination of genetic, environmental and lifestyle factors. This complex etiology creates challenges when it comes to diagnostics, follow-up programs and treatment. Although exact disease mechanisms are yet to be elucidate

The surface area of a building that could potentially be used for Building Integrated Photovoltaics would increase dramatically with the availability of transparent solar cells that could replace windows. The challenge is to capture energy from outside the visible region (UV or IR) while simultaneously allowing a high-quality observation of the outside world and transmitting sufficient light in th

BackgroundCancer-associated fibroblasts (CAFs) comprise a heterogeneous population of stromal cells within the tumour microenvironment. CAFs exhibit both tumour-promoting and tumour-suppressing functions, making them exciting targets for improving cancer treatments. Careful isolation, identification, and characterisation of CAF heterogeneity is thus necessary for ex vivo validation and future impl

Two key challenges for governing and managing critical infrastructure risk and resilience are interdependencies between infrastructures and the multi-actor setting in which they operate. This paper looks beyond the Critical Infrastructure (CI) field of research to identify and discuss cross-disciplinary approaches to address these challenges. It explores two related and slightly overlapping resear

Background: Despite EU regulatory standards, many workers suffer injury as a result of working with hand-held vibrating tools. Our aim of this study was to confirm whether carpenters, a highly exposed group, suffer more injuries to their hands than painters, a group assumed to be less exposed to vibration. Methods: 193 carpenters (participation rate 100%) and 72 painters (participation rate 67%),

This study contributes to the extant research on foreclosure by focusing on the relevance of lender-borrower relations. Donald Black’s theory of the behaviour of law is assessed by examining the association between revocation of compulsory sale by the lender and four different variables, proxying variations in the scope, history, and frequency of contact between the lender and the borrower. This a

Objectives: HLA-DQ2 and DQ8 contribute to the strongest risk haplotypes for type 1 diabetes (T1D) and celiac disease (CD). The variation in genetic risk association is likely linked to different HLA class II loci susceptibility, but association studies of HLA class I alleles are scarce. The aim was to investigate HLA class I A, B, and C alleles polymorphisms in children with only T1D, CD, and a su

A presentation of the doctoral conferment ceremony and its insignia and symbols.

Background. Recently, the Occupational Balance Questionnaire developed in Sweden was translated into Norwegian. No studies to date have examined the measurement properties of the Norwegian version of this questionnaire. Aim. The study is aimed at examining the psychometric properties of the Norwegian version of the Occupational Balance Questionnaire, the OBQ11-N. Methods. Along with sociodemograph

BACKGROUND: It is unclear how the length of prehospital transport time affects outcome in paediatric trauma. This study evaluated the association of transport time from alarm to arrival at hospital with adverse outcome in paediatric trauma patients in Sweden. METHODS: This was a retrospective study based on prospectively collected data from the Swedish trauma registry between 2012 and 2019 of chil

Objective The current study aimed to check whether early vascular aging, measured as carotid-femoral pulse wave velocity (cfPWV), is related to kidney function, measured as creatinine-based estimated glomerular filtration (eGFR) and urinary albumin-to-creatinine ratio (UACR), in middle-aged subjects with metabolic syndrome. Methods Participants were recruited from Lithuanian high-risk cohort (LitH

Heat transfer from the human body, especially through the evaporation of sweat from the skin, is often restricted when protective clothing is used, which may result in overheating. For this reason, it is important to consider the parameters of protective clothing as input data in physiological models, such as predicted heat strain. The two most important parameters are thermal insulation and evapo

When semiotics of architectural space turns from an interest in the visual revelation of a space “hidden” behind city plans or types of building facades, and focuses more on the socio-logical or narrato-logical interaction between humans, rules and matter, the subject of investigation (i.e. space) consequently turns more corporeal, more situation-based, and more political. In his philosophy of spa

AbstractDe senaste årtiondena så har shoppingens geografiska manifestationer förändrats i grunden. Den förmodade ”döden” som har förutspåtts för shopping i stadskärnor har blivit alltmer angeläget. Vetenskapliga studier har undersökt de sociala, kulturella och ekonomiska orsakerna till shoppingens decentralisering och dess effekter på stadslivet. Få studier har dock hittills fokuserat på den föränDuring recent decades, shopping’s geographical manifestations have altered radically and the presumed ‘death’ of town centre retailing has become a public concern. The social, cultural, and economic backgrounds of this decentralisation of retail and its effects on city life have been studied comprehensively. However, to date, few studies have examined the changing dynamics of non-mainstream shoppi

Adipocytes are primary targets for insulin control of metabolism. The activated insulin receptor phosphorylates insulin receptor substrate-1 (IRS1), which acts as a docking protein for downstream signal mediators. In the absence of insulin stimulation, IRS1 in rat adipocytes is intracellular but in human adipocytes IRS1 is constitutively targeted to the plasma membrane. Stimulation of adipocytes w

LGBTI Politics and Value Change in Ukraine and Turkey focuses on the impact of European Union promotion of LGBTI rights in Turkey and Ukraine, offering a re-evaluation of the mechanisms used by the EU and the domestic and external conditions that result in different outcomes. With the protection of LGBTI rights becoming one of the core principles of the EU, the last two decades have seen a consist

Minnesteckning, professor KTH