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Responsibility and Ambivalence

I use the concept of ambivalence—the state of being faced with a choice that cannot be resolved without sacrificing something of value—to approach five contemporary debates in the philosophy of moral responsibility: (1) psychopathy, (2) free will, (3) the emotion of guilt, (4) regret and indirect moral luck, and (5) moral demandingness. Rather than arguing for one theory or another, acknowledging

Quality Control in ECG-based Atrial Fibrillation Screening

This thesis comprises an introductory chapter and four papers related to quality control in ECG-based atrial fibrillation (AF) screening. Atrial fibrillation is a cardiac arrhythmia characterized by an irregular rhythm and constitutes a major risk factor for stroke. Anticoagulation therapy significantly reduces this risk, and therefore, AF screening is motivated. Atrial fibrillation screening is o

Gender (in)equality within the Swedish Armed Forces : Resistance and Functional Disinclination

Historically and traditionally, military work has been closely associated with men. However, the post-Cold War normalization process has brought about a transformation in both the Swedish Armed Forces themselves and the perception of the organization. Normative concerns, including gender equality, have gained significant prominence, compelling the armed forces to embark on various initiatives aime

CenTauR : Toward a universal scale and masks for standardizing tau imaging studies

INTRODUCTION: Recently, an increasing number of tau tracers have become available. There is a need to standardize quantitative tau measures across tracers, supporting a universal scale. We developed several cortical tau masks and applied them to generate a tau imaging universal scale. METHOD: One thousand forty-five participants underwent tau scans with either 18F-flortaucipir, 18F-MK6240, 18F-PI2

Genetic Moderation of the Association of β-Amyloid With Cognition and MRI Brain Structure in Alzheimer Disease

Background and Objectives: There is considerable heterogeneity in the association between increasing β-amyloid (Aβ) pathology and early cognitive dysfunction in preclinical Alzheimer disease (AD). At this stage, some individuals show no signs of cognitive dysfunction, while others show clear signs of decline. The factors explaining this heterogeneity are particularly important for understanding pr

Evaluation of single-fraction high dose FLASH radiotherapy in a cohort of canine oral cancer patients

Background: FLASH radiotherapy (RT) is a novel method for delivering ionizingradiation, which has been shown in preclinical studies to have a normal tissuesparing effect and to maintain anticancer efficacy as compared to conventionalRT. Treatment of head and neck tumors with conventional RT is commonlyassociated with severe toxicity, hence the normal tissue sparing effect of FLASHRT potentially ma

Rethinking bioeconomy innovation in sustainability transitions

Over the past two decades, a new research field dealing with “sustainability transitions” has emerged, analyzing the transformation of socio-technical systems towards more sustainable futures. While there is consensus on the crucial role of the bioeconomy in sustainability transitions research, we argue that the true potential of many bioeconomy innovations is not yet sufficiently recognized and a

Could Easier Access to University Improve Health and Reduce Health Inequalities?

This paper estimates the impact of university education on medical care use and its income related inequality. We do this by exploiting an arbitrary university eligibility rule in Sweden combined with regression discontinuity design for the years 2003-2013 for students who graduated 2003-2005. We find a clear jump in university attendance due to university eligibility. This jump coincides with a pThis paper estimates the impact of university education on medical care use and its income related inequality. We do this by exploiting an arbitrary university eligibility rule in Sweden combined with regression discontinuity design for the years 2003-2013 for students who graduated 2003-2005. We find a clear jump in university attendance due to university eligibility. This jump coincides with a p

Media and migration through the lens of mediatization and transnationalism

In present paper, the debates around mediatization and transnationalism constitute the backdrop for a discussion on the media and communication practices among Swedish expatriates in the Netherlands and forced migrants from Bosnia in Sweden. The complex relationship between (transnational) identity, place and mobility is studied at three intersections between media and migration: (1) creativity an

The self-organization of plant microtubules inside the cell volume yields their cortical localization, stable alignment, and sensitivity to external cues

Many cell functions rely on the ability of microtubules to self-organize as complex networks. In plants, cortical microtubules are essential to determine cell shape as they guide the deposition of cellulose microfibrils, and thus control mechanical anisotropy of the cell wall. Here we analyze how, in turn, cell shape may influence microtubule behavior. Buidling upon previous models that confined m

Analysis of nanoparticle biomolecule complexes

Nanoparticles exposed to biological fluids adsorb biomolecules on their surface forming a biomolecular corona. This corona determines, on a molecular level, the interactions and impact the newly formed complex has on cells and organisms. The corona formation as well as the physiological and toxicological relevance are commonly investigated. However, an acknowledged but rarely addressed problem in

Vulnerability of Ghanaian women cocoa farmers to climate change : a typology

Climate change, increasingly recognized as a hurdle to achieving sustainable development goals, has already begun impacting the lives and livelihoods of people around the world, including on the African continent. Vulnerability is a concept often employed in the context of climate change to identify risks and develop policy and adaptation measures that address current and projected impacts. Howeve

BEHAVIOURAL IMPLICATIONS OF EMPLOYEE-DRIVEN INNOVATION — A CRITICAL DISCOURSE ANALYSIS

This paper examines a digital employee-oriented innovation program at a global IT-firm. It addresses the research question: how is the generation and promotion of employee ideas organised by the management, and what are the behavioural implications in terms of participation of such an organising? Drawing on the literature on inclusive innovation and employee-driven innovation, the authors explore

On Goal Oriented Time Adaptivity using Local Error Estimates

We consider adaptive time discretization methods for ordinary differential equations where one aims to control the error in a quantity of interest of the form J(u) = ∫ j(u(t))dt with j : Rd -> R. In this setting we propose a new timestep controller based on local error estimates of the quantity of interest. The new method converges when the tolerance goes to zero.We experimentally compare the new

The bodies of others in Swedish feminism

The body – or, more specifically, women’s bodies – has long been one of feminism’s central topics. This discussion has ranged from explorations of the cultural meaning of biology to the challenging of classification systems regulating bodies not only culturally coded as female or male but also understood through race regimes. This article seeks to explore the location of bodies within Swedish femi

The ‘European Turks’ : identities of high-skilled Turkish migrants in Europe

Using exceptionally rich qualitative data coming from the FP7 EUCROSS project on the ‘Europeanization of the Everyday Life’, this paper focuses on high-skilled and highly transnational Turkish migrants who reside in the UK, Romania and Italy. The article analyses participants’ discursive constructions of Europe and Europeanness and shows how specific images and symbols of Europe and Turkey influen