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Search for Displaced Leptons in s =13 TeV pp Collisions with the ATLAS Detector

A search for charged leptons with large impact parameters using 139 fb-1 of s=13 TeV pp collision data from the ATLAS detector at the LHC is presented, addressing a long-standing gap in coverage of possible new physics signatures. Results are consistent with the background prediction. This search provides unique sensitivity to long-lived scalar supersymmetric lepton partners (sleptons). For lifeti

Unlocking the health system barriers to maximise the uptake and utilisation of molecular diagnostics in low-income and middle-income country setting

Background Early access to diagnosis is crucial for effective management of any disease including tuberculosis (TB). We investigated the barriers and opportunities to maximise uptake and utilisation of molecular diagnostics in routine healthcare settings. Methods Using the implementation of WHO approved TB diagnostics, Xpert Mycobacterium tuberculosis/rifampicin (MTB/RIF) and Line Probe Assay (LPA

Rugged relief and climate promote isolation and divergence between two neotropical cold-associated birds

The role of historical factors in establishing patterns of diversity in tropical mountains is of interest to understand the buildup of megadiverse biotas. In these regions, the historical processes of range fragmentation and contraction followed by dispersal are thought to be mediated by the interplay between rugged relief (complex topography) and climate fluctuations and likely explain most of th

The micrometeorite flux to Earth through the Phanerozoic Eon : Reconstructed using sediment-dispersed extraterrestrial spinels

The purpose of this thesis is to add an astronomical component to the history and evolution of Earth by reconstructing the micrometeorite flux to Earth at different time intervals during the Phanerozoic Eon, using sediment-dispersed extraterrestrial spinel group minerals as a proxy. Chromite and chrome spinel are common refractory members of the spinel group, occurring in both extraterrestrial and

Tickling tensions : Gazing into the parallax gap of the multicultural imaginary

This article explores why cultural branding – ideo-affective market communication addressing intense political tensions – paradoxically seems to lead to political inertia rather than political mobilization. I critically analyse advertising addressing political tensions related to race, ethnicity and immigration, but instead of only following the traced-out trajectory of postcolonial theory, I use

Cumulative exposure to melphalan chemotherapy and subsequent risk of developing acute myeloid leukemia and myelodysplastic syndromes in patients with multiple myeloma

Objectives: The aim of this study was to determine risk factors for development of acute myeloid leukemia/myelodysplastic syndromes (AML/MDS) in patients with multiple myeloma (MM). Methods: We identified all patients diagnosed with MM in Sweden from January 1st, 1958 to December 31, 2011. A total of 26 627 patients were diagnosed with MM with during the study period. Of these, 124 patients (0.5%)

Total Facility Management

This new edition includes a greater focus on applicable ISO standards in facility management as well as maintaining an international perspective throughout. It covers: the fundamentals of facility management, including key roles, responsibilities and accountabilities and the core competencies of facility management; an exploration of facility planning, facility management strategy, outsourcing, pr

Biomarkers after Controlled Inhalation Exposure to Exhaust from Hydrogenated Vegetable Oil (HVO)

Hydrogenated vegetable oil (HVO) is a renewable diesel fuel used to replace petroleum diesel. The organic compounds in HVO are poorly characterized; therefore, toxicological properties could be different from petroleum diesel exhaust. The aim of this study was to evaluate the exposure and effective biomarkers in 18 individuals after short-term (3 h) exposure to HVO exhaust and petroleum diesel exh

ESPRESSO mass determination of TOI-263b : An extreme inhabitant of the brown dwarf desert

The TESS mission has reported a wealth of new planetary systems around bright and nearby stars amenable for detailed characterizations of planet properties and atmospheres. However, not all interesting TESS planets orbit around bright host stars. TOI-263 b is a validated ultra-short-period substellar object in a 0.56-day orbit around a faint (V = 18.97) M 3.5 dwarf star. The substellar nature of T

Intracellular and Intercellular Mitochondrial Dynamics in Parkinson's Disease

The appearance of alpha-synuclein-positive inclusion bodies (Lewy bodies) and the loss of catecholaminergic neurons are the primary pathological hallmarks of Parkinson's disease (PD). However, the dysfunction of mitochondria has long been recognized as a key component in the progression of the disease. Dysfunctional mitochondria can in turn lead to dysregulation of calcium homeostasis and, especia

Characteristic value of the modulus of elasticity (MOE) for natural and planted larch in northeast China

The density and modulus of elasticity (MOE) distribution can provide information on the effectiveness of parametric and non-parametric methods in calculating the characteristic value of MOE. In this study, we aim to determine the optimal distribution model of the actual measured data of the lumber. We also estimate the lumber’s MOE characteristic value and compare the difference in density and MOE

The pediatric precision oncology INFORM registry : clinical outcome and benefit for patients with very high-evidence targets

INFORM is a prospective, multi-national registry gathering clinical and molecular data of relapsed, progressive or high-risk pediatric cancer patients. This report describes long-term follow-up of 519 patients in whom molecular alterations were evaluated according to a pre-defined 7-scale target prioritization algorithm. Mean turnaround time from sample receipt to report was 25.4 days. The highest

Preparedness for family caregiving prior to allogeneic hematopoietic stem cell transplantation

Objective Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a curative treatment associated with high morbidity and mortality. It is often necessary for family caregivers to become highly involved in the care, especially when patients return home after a long period of inpatient care. Family caregivers' preparedness for the tasks and demands of the caregiving role prior to allo-HSC