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Trends of Dispensed Opioids in Catalonia, Spain, 2007–19 : A Population-Based Cohort Study of Over 5 Million Individuals

Objective: To characterize the trend of opioid use (number of users, dispensations and oral morphine milligram equivalents) in Catalonia (Spain). Design, setting, and participants: This population-based cohort study included all individuals aged 18 years or older, registered in the Information System for Research in Primary Care (SIDIAP), which covers >75% of the population in Catalonia, Spain, fr

A climate risk analysis of Earth's forests in the 21st century

Earth's forests harbor extensive biodiversity and are currently a major carbon sink. Forest conservation and restoration can help mitigate climate change; however, climate change could fundamentally imperil forests in many regions and undermine their ability to provide such mitigation. The extent of climate risks facing forests has not been synthesized globally nor have different approaches to qua

The association of physical activity to oral glucose tolerance test outcomes in multiple autoantibody positive children : The TEDDY Study

Objective: To examine the association of physical activity (PA), measured by accelerometry, to hemoglobin AIC (HbA1c) and oral glucose tolerance test (OGTT) outcomes in children who were multiple persistent confirmed autoantibody positive for type 1 diabetes (T1D). Methods: The Environmental Determinants of Diabetes in the Young (TEDDY) multinational study followed children from birth. Children ≥3

Anastomotic leak following oesophagectomy : research priorities from an international Delphi consensus study

BACKGROUND: The Oesophago-Gastric Anastomosis Audit (OGAA) is an international collaborative group set up to study anastomotic leak outcomes after oesophagectomy for cancer. This Delphi study aimed to prioritize future research areas of unmet clinical need in RCTs to reduce anastomotic leaks.METHODS: A modified Delphi process was overseen by the OGAA committee, national leads, and engaged clinicia

Kläder under klubban : Begagnade kläder på landsbygdsauktioner i 1780-talets Blekinge

This article examines the access the people living in the countryside of the late 18th century south-Swedish district of Blekinge had to consumption with a focus on used clothes in the auction trade. Due to trade restrictions and the guild system, the peasantry’s access to consumption of goods was generally severely limited and specifically even more so in the access to both new and used clothes.