An analysis is presented of the likely statistical error and mathematical bias of experimental enzyme flux control coefficient estimates, calculated from observations of the flux changes caused by finite changes of the concentration of an enzyme in a metabolic pathway. The results indicate that such control coefficients are not likely to be determined with satisfactory precision unless the experim

A novel electrode array was developed based on the XNA on Gold(TM) microarray platform. The platform combines self-assembling monolayers, thick film patterning and streptavidin based immobilization to provide a robust, versatile platform capable of analysing virtually any biomolecule including nucleic acids, proteins, carbohydrates and lipids. Electrochemical analysis of the self-assembling monola

We review our recent work on the thermoseparating polymers in aqueous two-phase extractions of biomolecules. Random copolymers of ethylene oxide and propylene oxide (EOPO copolymers) are thermoseparating in water solution, i.e., at temperatures above the cloud point a concentrated copolymer phase and a water phase almost free of copolymer are formed. This phase behavior makes it possible to recycl

A new way of preparing catalytically active wire meshes through a thermal-spray technique is described. A metal substrate (e.g. Kanthal AF) was plasma-sprayed with a composite ceramic/polymer-powder. The polymer content of the sprayed layer was burnt off whereupon a well-defined macro-porosity was created. By treating the so obtained material with an alumina-sol the specific surface area could be

Mesenchymal stem cells (MSCs) are capable of down-regulating alloimmune responses and promoting the engraftment of hematopoietic stem cells. MSCs may therefore be suitable for improving donor-specific tolerance induction in solid-organ transplantation. Cells from cadaveric vertebral bone marrow (V-BM), aspirated iliac crest-BM, and peripheral blood progenitor cells were compared. Cells were charac

Vehicle rollover accidents are a particularly dangerous form of road accident. Existing vehicle dynamics controllers primarily deal with yaw stability, and are of limited use for dealing with problems of roll instability. This thesis deals with the development of a new type of vehicle dynamics control system, capable of preventing rollover accidents caused by extreme maneuvering. A control strateg

In this thesis we investigate the applicability of wavelets to simulate the time behavior of elastic multibody systems (MBS) with contact constraints. For this end, a wavelet element method (WEM) was implemented, exploiting the special structure of the coupled ODE/PDE equations that govern elastic MBS. Special care has to be taken to adapt the method to the particular geometry of the elastic bodi

Popular Abstract in Swedish Avhandlingen består av tre empiriska uppsatser inom internationell finansiell ekonomi. Den ekonometriska gemensamma nämnaren är att samtliga använda modeller är av komplex multivariat natur. Därför föreslås att de ekonometriska modellerna estimeras med hjälp av simulated annealing, en stokastisk optimeringsalgoritm som potentiellt löser de problem som vanligtvis är förkThis thesis consists of three self-contained empirical studies on international financial economics. The common economic theme is that all three studies deal with international stock market return and risk. The common econometric theme is that all estimations are performed using simulated annealing, a stochastic optimization algorithm in the Markov Chain Monte Carlo family, in an attempt to solve

Generation of charge pairs in a ladder-type poly(para-phenylene) was investigated by means of electric field modulated femtosecond pump-probe absorption spectroscopy upon excitation at 3.1 and 4.66 eV. Exciting at 3.1 eV in the optical S-0-->S-1 transition, the number of geminately bound electron-hole pairs rises smoothly within the entire exciton life time. Upon excitation at 4.66 eV an instantan

In January 1990 an expert group was set up by DP2 of TC2, CEC to define the research and development work needed to be undertaken within the community to achieve a robust solution with respect to reaction-to-fire material classification. The expert group delivered in December 1990 its proposal for a 5-year research and development program. But a system of harmonised European fire test methods and

Churches and elite in Trøndelag: A review of Jan Brendalsmos dissertation "Kirkebygg og kirkebyggere. Bygherrer i Trøndelag ca. 1000-1600" (Churuch buildings and church builders in Trøndelag ca. 1000-1600), Oslo 2006.

Popular Abstract in Swedish NÄR ÖRESUNDSBRON INVIGDES ÅR 2000 nådde förväntningarna på dansk-svensk integration sin kulmen. Prognoser och framtidsspekulationer haglade. Nyhetsbrev, reklamkampanjer, webbplatser och konferenser producerades på löpande band. Öresundsbron förenade Öresundsregionen. Öresundsregionen förenade skåningar och själlänningar. Tillsammans skulle de forna broderfolken skapa enThe Öresund Bridge between Denmark and Sweden was inaugurated in the year 2000, connecting the city of Malmö and the Danish capital Copenhagen. The bridge was an important move towards the visionary realisation of a transnational Öresund Region. In this dissertation the communicative aspects of the regional process are put in focus. The vision of the Öresund Region that developed during the 1990s

Cytogenetic and molecular cytogenetic analyses were performed on four sublines derived from a newly established, SV40T-immortalized nasopharyngeal (NP) cell line, NP69, with two of the sublines expressing LMP1, an Epstein-Barr virus-encoded gene. A total of seven cytogenetically related subclones were identified, all having highly complex karyotypes with massive numerical and structural rearrangem

Gliomas, in particular the high-grade anaplastic glioma and glioblastoma multiforme (GBM), are manifested by morphological, genetic and phenotypic heterogeneity. Most of the studies hitherto have been performed on bulk glioma cells, with limited understanding on the origin and the relative contribution of particular glioma cell populations to glioma growth and progression. Recent studies have demo

As part of a project to obtain better optical response functions for nanomaterials and other systems with strong excitonic effects, we here calculate the exchange-correlation (XC) potential of density functional theory (DFT) at a level of approximation which corresponds to the dynamically screened exchange or GW approximation. In this process, we have designed a numerical method based on cubic spl

The cytogenetic evolution of 32 Philadelphia (Ph)-positive chronic myeloid leukemias (CML) receiving interferon-alpha (IFN-alpha) therapy was compared to the patterns in untreated CML and cases treated with busulfan (Bu), hydroxyurea (Hy), and allogeneic bone marrow transplantation (BMT). Half of the CML receiving IFN-alpha had at least one of the well-known major or minor route aberrations wherea